Search Results - "BOONEN, Harrie C. M" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The evolving role of investigative toxicology in the pharmaceutical industry

The evolving role of investigative toxicology in the pharmaceutical industry

by Pognan, Francois, Beilmann, Mario, Boonen, Harrie C M, Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Oinonen, Teija, Roth, Adrian, Steger-Hartmann, Thomas, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J, Newham, Peter
Published in Nature reviews. Drug discovery (01.04.2023)

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Journal Article

Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

by Boonen, Harrie C. M., Moesgaard, Sophia G., Birck, Malene M., Christoffersen, Berit Ø., Cirera, Susanna, Heegaard, Peter M. H., Højbøge, Tina Rødgaard, Jensen, Lars J., Mortensen, Alan, Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, Jiaowei, Lykkesfeldt, Jens
Published in Pflügers Archiv (01.12.2014)

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Characterization of capsaicin induced responses in mice vas deferens: Evidence of CGRP uptake

Characterization of capsaicin induced responses in mice vas deferens: Evidence of CGRP uptake

by Sheykhzade, Majid, Gupta, Saurabh, Sørensen, Tinne, Sørensen, Ole Aabling, Koch, Hans, Boonen, Harrie C.M., Back, Ole, Fjalland, Bjarne
Published in European journal of pharmacology (30.09.2011)

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Journal Article

Increased Contractile Response to Noradrenaline Induced By Factors Associated with the Metabolic Syndrome in Cultured Small Mesenteric Arteries

Increased Contractile Response to Noradrenaline Induced By Factors Associated with the Metabolic Syndrome in Cultured Small Mesenteric Arteries

by Blædel, Martin, Sams, Anette, Boonen, Harrie C M, Sheykhzade, Majid
Published in Pharmacology (01.01.2016)

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New 3-Alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-Dioxide Derivatives Activate ATP-Sensitive Potassium Channels of Pancreatic Beta Cells

New 3-Alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-Dioxide Derivatives Activate ATP-Sensitive Potassium Channels of Pancreatic Beta Cells

by Nielsen, Flemming E, Ebdrup, Søren, Jensen, Anette Frost, Ynddal, Lars, Bodvarsdottir, Thora B, Stidsen, Carsten, Worsaae, Anne, Boonen, Harrie C. M, Arkhammar, Per O. G, Fremming, Tinna, Wahl, Philip, Kornø, Hanne T, Hansen, J. Bondo
Published in Journal of medicinal chemistry (13.07.2006)

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Journal Article

6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of Pancreatic β-Cells

6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of Pancreatic β-Cells

by Nielsen, Flemming E, Bodvarsdottir, Thora B, Worsaae, Anne, MacKay, Peter, Stidsen, Carsten E, Boonen, Harrie C. M, Pridal, Lone, Arkhammar, Per O. G, Wahl, Philip, Ynddal, Lars, Junager, Finn, Dragsted, Nils, Tagmose, Tina M, Mogensen, John P, Koch, Anette, Treppendahl, Svend P, Hansen, J. Bondo
Published in Journal of medicinal chemistry (12.09.2002)

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Journal Article

Lipopolysaccharides, but not Angiotensin ll, lnduces Direct Pro‐lnflammatory Effects in Cultured Mouse Arteries and Human Endothelial and Vascular Smooth Muscle Cells

Lipopolysaccharides, but not Angiotensin ll, lnduces Direct Pro‐lnflammatory Effects in Cultured Mouse Arteries and Human Endothelial and Vascular Smooth Muscle Cells

by Outzen, Emilie M., Zaki, Marina, Mehryar, Rahila, Abdolalizadeh, Bahareh, Sajid, Waseem, Boonen, Harrie C. M., Sams, Anette, Sheykhzade, Majid
Published in Basic & clinical pharmacology & toxicology (01.04.2017)

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Journal Article

Medicines combinations options and regulatory hurdles

Medicines combinations options and regulatory hurdles

by Bjerrum, Ole J., Gautam, Yvonne, Bjerrum, Esben J., Schmiegelow, Merete, Boonen, Harrie C.M.
Published in European journal of pharmaceutical sciences (16.07.2013)

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Journal Article Conference Proceeding

Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance‐sized arteries

Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance‐sized arteries

by Outzen, Emilie M., Zaki, Marina, Abdolalizadeh, Bahareh, Sams, Anette, Boonen, Harrie C. M., Sheykhzade, Majid
Published in Pharmacology research & perspectives (01.12.2015)

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Journal Article

Early Onset Inflammation in Pre-Insulin-Resistant Diet-Induced Obese Rats Does Not Affect the Vasoreactivity of Isolated Small Mesenteric Arteries

Early Onset Inflammation in Pre-Insulin-Resistant Diet-Induced Obese Rats Does Not Affect the Vasoreactivity of Isolated Small Mesenteric Arteries

by Blædel, Martin, Raun, Kirsten, Boonen, Harrie C.M., Sheykhzade, Majid, Sams, Anette
Published in Pharmacology (01.01.2012)

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Journal Article

Effect of Ageing on the Passive and Active Tension and Pharmacodynamic Characteristics of Rat Coronary Arteries: Age-Dependent Increase in Sensitivity to 5-HT and K

Effect of Ageing on the Passive and Active Tension and Pharmacodynamic Characteristics of Rat Coronary Arteries: Age-Dependent Increase in Sensitivity to 5-HT and K

by Sheykhzade, Majid, Simonsen, Anja Hviid, Boonen, Harrie C.M., Outzen, Emilie M., Nyborg, Niels C. Berg
Published in Pharmacology (01.01.2012)

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Journal Article

Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels

Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels

by SCHOU, Søren C, HANSEN, Holger C, LEBRUN, Philippe, HANSEN, John Bondo, TAGMOSE, Tina M, BOONEN, Harrie C. M, WORSAAE, Anne, DRABOWSKI, Michael, WAHL, Philip, ARKHAMMAR, Per O. G, BODVARSDOTTIR, Thora, ANTOINE, Marie-Hélène
Published in Bioorganic & medicinal chemistry (03.01.2005)

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Arylcyanoguanidines as Activators of Kir6.2/SUR1KATP Channels and Inhibitors of Insulin Release

Arylcyanoguanidines as Activators of Kir6.2/SUR1KATP Channels and Inhibitors of Insulin Release

by Tagmose, Tina M, Schou, Søren C, Mogensen, John P, Nielsen, Flemming E, Arkhammar, Per O. G, Wahl, Philip, Hansen, Birgit S, Worsaae, Anne, Boonen, Harrie C. M, Antoine, Marie-Hélène, Lebrun, Philippe, Hansen, John Bondo
Published in Journal of medicinal chemistry (03.06.2004)

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Journal Article

Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release

Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release

by Tagmose, Tina M, Schou, Søren C, Mogensen, John P, Nielsen, Flemming E, Arkhammar, Per O G, Wahl, Philip, Hansen, Birgit S, Worsaae, Anne, Boonen, Harrie C M, Antoine, Marie-Hélène, Lebrun, Philippe, Hansen, John Bondo
Published in Journal of medicinal chemistry (03.06.2004)

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Journal Article

Synthesis and biological activity of 3,3-Diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells

Synthesis and biological activity of 3,3-Diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells

by Tagmose, Tina M, Zaragoza, Florencio, Boonen, Harrie C.M, Worsaae, Anne, Mogensen, John P, Nielsen, Flemming E, Jensen, Anette Frost, Hansen, John Bondo
Published in Bioorganic & medicinal chemistry (20.03.2003)

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Journal Article

Mesenteric small artery changes after vasoconstrictor infusion in young rats

Mesenteric small artery changes after vasoconstrictor infusion in young rats

by Boonen, H C, Daemen, M J, Eerdmans, P H, Fazzi, G E, van Kleef, E M, Schiffers, P M, De Mey, J G
Published in Journal of cardiovascular pharmacology (01.09.1993)

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Journal Article

Effects of tertatolol on the responsiveness of isolated femoral, mesenteric, and renal resistance arteries to adrenergic stimuli

Effects of tertatolol on the responsiveness of isolated femoral, mesenteric, and renal resistance arteries to adrenergic stimuli

by Boonen, H C, Struyker-Boudier, H A, De Mey, J G
Published in Journal of cardiovascular pharmacology (01.01.1990)

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Journal Article

New 3-Alkylamino-4 H -thieno-1,2,4-thiadiazine 1,1-Dioxide Derivatives Activate ATP-Sensitive Potassium Channels of Pancreatic Beta Cells

New 3-Alkylamino-4 H -thieno-1,2,4-thiadiazine 1,1-Dioxide Derivatives Activate ATP-Sensitive Potassium Channels of Pancreatic Beta Cells

by Nielsen, Flemming E., Ebdrup, Søren, Jensen, Anette Frost, Ynddal, Lars, Bodvarsdottir, Thora B., Stidsen, Carsten, Worsaae, Anne, Boonen, Harrie C. M., Arkhammar, Per O. G., Fremming, Tinna, Wahl, Philip, Kornø, Hanne T., Hansen, J. Bondo
Published in Journal of medicinal chemistry (01.07.2006)

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Journal Article

6-Chloro-3-alkylamino-4 H -thieno[3,2 -e ]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of Pancreatic β-Cells

6-Chloro-3-alkylamino-4 H -thieno[3,2 -e ]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of Pancreatic β-Cells

by Nielsen, Flemming E., Bodvarsdottir, Thora B., Worsaae, Anne, MacKay, Peter, Stidsen, Carsten E., Boonen, Harrie C. M., Pridal, Lone, Arkhammar, Per O. G., Wahl, Philip, Ynddal, Lars, Junager, Finn, Dragsted, Nils, Tagmose, Tina M., Mogensen, John P., Koch, Anette, Treppendahl, Svend P., Hansen, J. Bondo
Published in Journal of medicinal chemistry (01.09.2002)

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Journal Article

G-proteins are involved in contractile responses of isolated mesenteric resistance arteries to agonists

G-proteins are involved in contractile responses of isolated mesenteric resistance arteries to agonists

by Boonen, H C, De Mey, J G
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.10.1990)

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