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Wang, Yuan Yuan, Attané, Camille, Milhas, Delphine, Dirat, Béatrice, Dauvillier, Stéphanie, Guerard, Adrien, Gilhodes, Julia, Lazar, Ikrame, Alet, Nathalie, Laurent, Victor, Le Gonidec, Sophie, Biard, Denis, Hervé, Caroline, Bost, Frédéric, Ren, Guo Sheng, Bono, Françoise, Escourrou, Ghislaine, Prentki, Marc, Nieto, Laurence, Valet, Philippe, Muller, Catherine
Published in JCI insight (23.02.2017)
Published in JCI insight (23.02.2017)
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Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
Favier, Benoit, Alam, Antoine, Barron, Pauline, Bonnin, Jacques, Laboudie, Patricia, Fons, Pierre, Mandron, Marie, Herault, Jean-Pascal, Neufeld, Gera, Savi, Pierre, Herbert, Jean-Marc, Bono, Françoise
Published in Blood (15.08.2006)
Published in Blood (15.08.2006)
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Conversion of human fibroblasts to angioblast-like progenitor cells
Kurian, Leo, Sancho-Martinez, Ignacio, Nivet, Emmanuel, Aguirre, Aitor, Moon, Krystal, Pendaries, Caroline, Volle-Challier, Cecile, Bono, Francoise, Herbert, Jean-Marc, Pulecio, Julian, Xia, Yun, Li, Mo, Montserrat, Nuria, Ruiz, Sergio, Dubova, Ilir, Rodriguez, Concepcion, Denli, Ahmet M, Boscolo, Francesca S, Thiagarajan, Rathi D, Gage, Fred H, Loring, Jeanne F, Laurent, Louise C, Izpisua Belmonte, Juan Carlos
Published in Nature methods (01.01.2013)
Published in Nature methods (01.01.2013)
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The Active Metabolite of Clopidogrel Disrupts P2Y12 Receptor Oligomers and Partitions Them out of Lipid Rafts
Savi, Pierre, Zachayus, Jean-Luc, Delesque-Touchard, Nathalie, Labouret, Catherine, Hervé, Caroline, Uzabiaga, Marie-Françoise, Pereillo, Jean-Marie, Culouscou, Jean-Michel, Bono, Françoise, Ferrara, Pascual, Herbert, Jean-Marc
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2006)
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A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamics of AsiDNA, a first-in-class DNA repair inhibitor, administered intravenously in patients with advanced solid tumours
Le Tourneau, Christophe, Delord, Jean-Pierre, Kotecki, Nuria, Borcoman, Edith, Gomez-Roca, Carlos, Hescot, Ségolène, Jungels, Christiane, Vincent-Salomon, Anne, Cockenpot, Vincent, Eberst, Lauriane, Molé, Audrey, Jdey, Wael, Bono, Françoise, Trochon-Joseph, Véronique, Toussaint, Hélène, Zandanel, Christelle, Adamiec, Olga, de Beaumont, Olivier, Cassier, Philippe Alexandre
Published in British journal of cancer (10.11.2020)
Published in British journal of cancer (10.11.2020)
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Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells
Chamboredon, Sandrine, Ciais, Delphine, Desroches-Castan, Agnès, Savi, Pierre, Bono, Françoise, Feige, Jean-Jacques, Cherradi, Nadia
Published in Molecular biology of the cell (15.09.2011)
Published in Molecular biology of the cell (15.09.2011)
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Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling
Herbert, Corentin, Schieborr, Ulrich, Saxena, Krishna, Juraszek, Jarek, De Smet, Frederik, Alcouffe, Chantal, Bianciotto, Marc, Saladino, Giorgio, Sibrac, David, Kudlinzki, Denis, Sreeramulu, Sridhar, Brown, Alan, Rigon, Patrice, Herault, Jean-Pascal, Lassalle, Gilbert, Blundell, Tom L., Rousseau, Frederic, Gils, Ann, Schymkowitz, Joost, Tompa, Peter, Herbert, Jean-Marc, Carmeliet, Peter, Gervasio, Francesco Luigi, Schwalbe, Harald, Bono, Françoise
Published in Cancer cell (15.04.2013)
Published in Cancer cell (15.04.2013)
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Preclinical evidence that SSR128129E – A novel small-molecule multi-fibroblast growth factor receptor blocker – Radiosensitises human glioblastoma
Ader, Isabelle, Delmas, Caroline, Skuli, Nicolas, Bonnet, Jacques, Schaeffer, Paul, Bono, Françoise, Cohen-Jonathan-Moyal, Elizabeth, Toulas, Christine
Published in European journal of cancer (1990) (01.09.2014)
Published in European journal of cancer (1990) (01.09.2014)
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N‑[6-(4-Butanoyl-5-methyl‑1H‑pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]‑1H‑indole-3-carboxamide (SAR216471), a Novel Intravenous and Oral, Reversible, and Directly Acting P2Y12 Antagonist
Boldron, Christophe, Besse, Angélina, Bordes, Marie-Françoise, Tissandié, Stéphanie, Yvon, Xavier, Gau, Benjamin, Badorc, Alain, Rousseaux, Tristan, Barré, Guillaume, Meneyrol, Jérôme, Zech, Gernot, Nazare, Marc, Fossey, Valérie, Pflieger, Anne-Marie, Bonnet-Lignon, Sandrine, Millet, Laurence, Briot, Christophe, Dol, Frédérique, Hérault, Jean-Pascal, Savi, Pierre, Lassalle, Gilbert, Delesque, Nathalie, Herbert, Jean-Marc, Bono, Françoise
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Regulator of G-protein signaling 18 controls both platelet generation and function
Delesque-Touchard, Nathalie, Pendaries, Caroline, Volle-Challier, Cécile, Millet, Laurence, Salel, Véronique, Hervé, Caroline, Pflieger, Anne-Marie, Berthou-Soulie, Laurence, Prades, Catherine, Sorg, Tania, Herbert, Jean-Marc, Savi, Pierre, Bono, Françoise
Published in PloS one (18.11.2014)
Published in PloS one (18.11.2014)
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A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury
Delbary-Gossart, Sandrine, Lee, Sangmi, Baroni, Marco, Lamarche, Isabelle, Arnone, Michele, Canolle, Benoit, Lin, Amity, Sacramento, Jeffrey, Salegio, Ernesto A, Castel, Marie-Noelle, Delesque-Touchard, Nathalie, Alam, Antoine, Laboudie, Patricia, Ferzaz, Badia, Savi, Pierre, Herbert, Jean-Marc, Manley, Geoffrey T, Ferguson, Adam R, Bresnahan, Jacqueline C, Bono, Françoise, Beattie, Michael S
Published in Brain (London, England : 1878) (01.06.2016)
Published in Brain (London, England : 1878) (01.06.2016)
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5‑Chlorothiophene-2-carboxylic Acid [(S)‑2-[2-Methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor
Meneyrol, Jerome, Follmann, Markus, Lassalle, Gilbert, Wehner, Volkmar, Barre, Guillaume, Rousseaux, Tristan, Altenburger, Jean-Michel, Petit, Frederic, Bocskei, Zsolt, Schreuder, Herman, Alet, Nathalie, Herault, Jean-Pascal, Millet, Laurence, Dol, Frederique, Florian, Peter, Schaeffer, Paul, Sadoun, Freddy, Klieber, Sylvie, Briot, Christophe, Bono, Françoise, Herbert, Jean-Marc
Published in Journal of medicinal chemistry (12.12.2013)
Published in Journal of medicinal chemistry (12.12.2013)
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Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis
Delcourt, Nicolas, Quevedo, Celia, Nonne, Christelle, Fons, Pierre, O'Brien, Donogh, Loyaux, Denis, Diez, Maria, Autelitano, François, Guillemot, Jean-Claude, Ferrara, Pascual, Muriana, Arantza, Callol, Carlos, Hérault, Jean-Pascal, Herbert, Jean-Marc, Favre, Gilles, Bono, Françoise
Published in The Journal of biological chemistry (06.02.2015)
Published in The Journal of biological chemistry (06.02.2015)
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SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities
Alam, Antoine, Blanc, Isabelle, Gueguen-Dorbes, Geneviève, Duclos, Olivier, Bonnin, Jacques, Barron, Pauline, Laplace, Marie-Claude, Morin, Gaelle, Gaujarengues, Florence, Dol, Frédérique, Hérault, Jean-Pascal, Schaeffer, Paul, Savi, Pierre, Bono, Françoise
Published in Molecular cancer therapeutics (01.08.2012)
Published in Molecular cancer therapeutics (01.08.2012)
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Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes
MacDonald, Douglas A., Martin, Joel, Muthusamy, Kathir K., Luo, Jiann-Kae, Pyles, Erica, Rafique, Ashique, Huang, Tammy, Potocky, Terra, Liu, Yang, Cao, Jingtai, Bono, Françoise, Delesque, Nathalie, Savi, Pierre, Francis, John, Amirkhosravi, Ali, Meyer, Todd, Romano, Carmelo, Glinka, Meredith, Yancopoulos, George D., Stahl, Neil, Wiegand, Stanley J., Papadopoulos, Nicholas
Published in Angiogenesis (London) (01.07.2016)
Published in Angiogenesis (London) (01.07.2016)
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Author Correction: Conversion of human fibroblasts to angioblast-like progenitor cells
Kurian, Leo, Sancho-Martinez, Ignacio, Nivet, Emmanuel, Aguirre, Aitor, Moon, Krystal, Pendaries, Caroline, Volle-Challier, Cecile, Bono, Francoise, Herbert, Jean-Marc, Pulecio, Julian, Xia, Yun, Li, Mo, Montserrat, Nuria, Ruiz, Sergio, Dubova, Ilir, Rodriguez, Concepcion, Denli, Ahmet M, Boscolo, Francesca S, Thiagarajan, Rathi D, Gage, Fred H, Loring, Jeanne F, Laurent, Louise C, Belmonte, Juan Carlos Izpisua
Published in Nature methods (01.03.2020)
Published in Nature methods (01.03.2020)
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Tumor Vasculature Is Regulated by FGF/FGFR Signaling-Mediated Angiogenesis and Bone Marrow-Derived Cell Recruitment: This Mechanism Is Inhibited by SSR128129E, the First Allosteric Antagonist of FGFRs
Fons, Pierre, Gueguen-Dorbes, Geneviève, Herault, Jean-Pascal, Geronimi, Fabien, Tuyaret, Joël, Frédérique, Dol, Schaeffer, Paul, Volle-Challier, Cécile, Herbert, Jean-Marc, Bono, Françoise
Published in Journal of cellular physiology (01.01.2015)
Published in Journal of cellular physiology (01.01.2015)
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Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling
Herbert, Corentin, Schieborr, Ulrich, Saxena, Krishna, Juraszek, Jarek, De Smet, Frederik, Alcouffe, Chantal, Bianciotto, Marc, Saladino, Giorgio, Sibrac, David, Kudlinzki, Denis, Sreeramulu, Sridhar, Brown, Alan, Rigon, Patrice, Herault, Jean-Pascal, Lassalle, Gilbert, Blundell, Tom L., Rousseau, Frederic, Gils, Ann, Schymkowitz, Joost, Tompa, Peter, Herbert, Jean-Marc, Carmeliet, Peter, Gervasio, Francesco Luigi, Schwalbe, Harald, Bono, Françoise
Published in Cancer cell (11.07.2016)
Published in Cancer cell (11.07.2016)
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Targeting Tumor Angiogenesis with the Selective VEGFR-3 Inhibitor EVT801 in Combination with Cancer Immunotherapy
Paillasse, Michael R, Esquerré, Michael, Bertrand, Florie A, Poussereau-Pomié, Céline, Pichery, Mélanie, Visentin, Virgile, Gueguen-Dorbes, Geneviève, Gaujarengues, Florence, Barron, Pauline, Badet, Gaelle, Briaux, Anne, Ancey, Pierre-Benoit, Sibrac, David, Erdociain, Eric, Özcelik, Dennis, Meneyrol, Jérôme, Martin, Valérie, Gomez-Brouchet, Anne, Selves, Janik, Rochaix, Philippe, Battistella, Maxime, Lebbé, Céleste, Delord, Jean-Pierre, Dol-Gleizes, Frédérique, Bono, Françoise, Blanc, Isabelle, Alam, Antoine, Hunneyball, Ian, Whittaker, Mark, Fons, Pierre
Published in Cancer research communications (01.11.2022)
Published in Cancer research communications (01.11.2022)
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