The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
Massie, Charles E, Lynch, Andy, Ramos-Montoya, Antonio, Boren, Joan, Stark, Rory, Fazli, Ladan, Warren, Anne, Scott, Helen, Madhu, Basetti, Sharma, Naomi, Bon, Helene, Zecchini, Vinny, Smith, Donna-Michelle, DeNicola, Gina M, Mathews, Nik, Osborne, Michelle, Hadfield, James, MacArthur, Stewart, Adryan, Boris, Lyons, Scott K, Brindle, Kevin M, Griffiths, John, Gleave, Martin E, Rennie, Paul S, Neal, David E, Mills, Ian G
Published in The EMBO journal (06.07.2011)
Published in The EMBO journal (06.07.2011)
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Journal Article
The effect of TG2-inhibitory monoclonal antibody zampilimab on tissue fibrosis in human in vitro and primate in vivo models of chronic kidney disease
Huang, Linghong, Bon, Helene, Maamra, Mabrouka, Holmes, Toby, Atkinson, John, Cain, Katharine, Kennedy, Jeff, Kettleborough, Catherine, Matthews, David, Twomey, Breda, Ni, Jia, Song, Zhizhan, Watson, Philip F, Johnson, Timothy S
Published in PloS one (16.05.2024)
Published in PloS one (16.05.2024)
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Journal Article
Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer
Bon, Hélène, Wadhwa, Karan, Schreiner, Alexander, Osborne, Michelle, Carroll, Thomas, Ramos-Montoya, Antonio, Ross-Adams, Helen, Visser, Matthieu, Hoffmann, Ralf, Ahmed, Ahmed Ashour, Neal, David E, Mills, Ian G
Published in Molecular cancer research (01.04.2015)
Published in Molecular cancer research (01.04.2015)
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Journal Article
An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix
Qureshi, Omar S, Bon, Hélène, Twomey, Breda, Holdsworth, Gill, Ford, Kirsty, Bergin, Marianne, Huang, Linghong, Muzylak, Mariusz, Healy, Louise J, Hurdowar, Vanessa, Johnson, Timothy S
Published in Biology open (15.10.2017)
Published in Biology open (15.10.2017)
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Journal Article
Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ
Holdsworth, Gill, Bon, Hélène, Bergin, Marianne, Qureshi, Omar, Paveley, Ross, Atkinson, John, Huang, Linghong, Tewari, Roohi, Twomey, Breda, Johnson, Timothy
Published in Scientific reports (30.08.2017)
Published in Scientific reports (30.08.2017)
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Assessment of Ultra-Deep Mass Spectrometry Based Proteomics Compared to Flow Cytometry and RNA-Based Methods for the Discovery and Validation of Therapeutic Targets in Immune Cells
Au, Yu-Wah, Rigter, Gemma, Yu, Wingyan, Satijn, David, Mehnert, Martin, Lachaud, Amaury, Vowinckel, Jakob, Neijssen, Joost, Bon, Helene
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling
Maamra, Mabrouka, Benayad, Osama Mehdi, Matthews, David, Kettleborough, Catherine, Atkinson, John, Cain, Katharine, Bon, Helene, Brand, Helen, Parkinson, Michael, Watson, Philip F., Johnson, Timothy S.
Published in British journal of pharmacology (01.06.2022)
Published in British journal of pharmacology (01.06.2022)
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Journal Article
The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer
Sharma, Naomi L, Massie, Charlie E, Butter, Falk, Mann, Matthias, Bon, Helene, Ramos-Montoya, Antonio, Menon, Suraj, Stark, Rory, Lamb, Alastair D, Scott, Helen E, Warren, Anne Y, Neal, David E, Mills, Ian G
Published in Nucleic acids research (02.06.2014)
Published in Nucleic acids research (02.06.2014)
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Journal Article
HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network
Ramos‐Montoya, Antonio, Lamb, Alastair D, Russell, Roslin, Carroll, Thomas, Jurmeister, Sarah, Galeano‐Dalmau, Nuria, Massie, Charlie E, Boren, Joan, Bon, Helene, Theodorou, Vasiliki, Vias, Maria, Shaw, Greg L, Sharma, Naomi L, Ross‐Adams, Helen, Scott, Helen E, Vowler, Sarah L, Howat, William J, Warren, Anne Y, Wooster, Richard F, Mills, Ian G, Neal, David E
Published in EMBO molecular medicine (01.05.2014)
Published in EMBO molecular medicine (01.05.2014)
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Journal Article
HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E 2 F 1‐mediated cell cycle network
Ramos‐Montoya, Antonio, Lamb, Alastair D, Russell, Roslin, Carroll, Thomas, Jurmeister, Sarah, Galeano‐Dalmau, Nuria, Massie, Charlie E, Boren, Joan, Bon, Helene, Theodorou, Vasiliki, Vias, Maria, Shaw, Greg L, Sharma, Naomi L, Ross‐Adams, Helen, Scott, Helen E, Vowler, Sarah L, Howat, William J, Warren, Anne Y, Wooster, Richard F, Mills, Ian G, Neal, David E
Published in EMBO molecular medicine (01.05.2014)
Published in EMBO molecular medicine (01.05.2014)
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Journal Article
인간 TGFB1, TGFB2에, 및 TGFB3에 결합하는 길항제 항체, 및 폐 섬유증 치료를 위한 그의 용도
GOUVEIA SANCHO MARIA MARGARIDA, ELLIS MARK, TURNER ALISON, RASTRICK JOSEPH MICHAEL DAVID, JUPP RAYMOND ANTHONY, COMPSON JOANNE ELIZABETH, PAYNE ANDREW CHARLES, DOYLE CARL BRENDAN, TYSON KERRY LOUISE, DIXON KATE LOUISE, LIGHTWOOD DANIEL JOHN, MARSHALL DIANE, BON HELENE, KEVORKIAN LARA, SCHULZE MONIKA SARAH
Year of Publication 13.02.2019
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Year of Publication 13.02.2019
Patent
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis: AR coordinates anabolic program in prostate cancer
Massie, Charles E, Lynch, Andy, Ramos-Montoya, Antonio, Boren, Joan, Stark, Rory, Fazli, Ladan, Warren, Anne, Scott, Helen, Madhu, Basetti, Sharma, Naomi, Bon, Helene, Zecchini, Vinny, Smith, Donna-Michelle, DeNicola, Gina M, Mathews, Nik, Osborne, Michelle, Hadfield, James, MacArthur, Stewart, Adryan, Boris, Lyons, Scott K, Brindle, Kevin M, Griffiths, John, Gleave, Martin E, Rennie, Paul S, Neal, David E, Mills, Ian G
Published in The EMBO journal (06.07.2011)
Published in The EMBO journal (06.07.2011)
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Journal Article
Abstract 1714: Transcriptional networks downstream of the AR identify clinically relevant prostate cancer targets
Massie, Charlie, Lynch, Andy, Stark, Rory, Ramos-Montoya, Anthony, Fazli, Ladan, Warren, Anne, Scott, Helen, Bon, Helene, Sharma, Naomi, Zecchini, Vinny, Matthews, Nik, Osborne, Michelle, Hadfield, James, Swatton, Jane, McArthur, Stewart, Adryan, Boris, Grigorenko, Elena, Watt, Carolyn, McEwan, Iain, Rennie, Paul, Neal, David, Mills, Ian G.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Abstract 3974: Discovery and validation of therapeutic targets in immune cells by mass spectrometry-based proteomics
Au, Yu-Wah, Satijn, David, Mehnert, Martin, Lachaud, Amaury, Feng, Yuehan, Vowinckel, Jakob, Bon, Hélène
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Publisher Correction: Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ
Holdsworth, Gill, Bon, Hélène, Bergin, Marianne, Qureshi, Omar, Paveley, Ross, Atkinson, John, Huang, Linghong, Tewari, Roohi, Twomey, Breda, Johnson, Timothy
Published in Scientific reports (21.12.2017)
Published in Scientific reports (21.12.2017)
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Journal Article
Antagonist antibodies that bind to human TGFB1, TGFB2 and to TGFB3 and their use for the treatment of lung fibrosis
Schulze, Monika-Sarah, Marshall, Diane, Turner, Alison, Bon, Helene, Jupp, Raymond Anthony, Payne, Andrew Charles, Kevorkian, Lara, Rastrick, Joseph Michael David, Dixon, Kate Louise, Gouveia Sancho, Maria Margarida, Tyson, Kerry Louise, Compson, Joanne Elizabeth, Ellis, Mark, Lightwood, Daniel John, Doyle, Carl Brendan
Year of Publication 06.12.2022
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Year of Publication 06.12.2022
Patent