NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility
Kiyozumi, Daiji, Noda, Taichi, Yamaguchi, Ryo, Tobita, Tomohiro, Matsumura, Takafumi, Shimada, Kentaro, Kodani, Mayo, Kohda, Takashi, Fujihara, Yoshitaka, Ozawa, Manabu, Yu, Zhifeng, Miklossy, Gabriella, Bohren, Kurt M, Horie, Masato, Okabe, Masaru, Matzuk, Martin M, Ikawa, Masahito
Published in Science (American Association for the Advancement of Science) (05.06.2020)
Published in Science (American Association for the Advancement of Science) (05.06.2020)
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Journal Article
C–N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis
Chen, Ying-Chu, Faver, John C, Ku, Angela F, Miklossy, Gabriella, Riehle, Kevin, Bohren, Kurt M, Ucisik, Melek N, Matzuk, Martin M, Yu, Zhifeng, Simmons, Nicholas
Published in Bioconjugate chemistry (18.03.2020)
Published in Bioconjugate chemistry (18.03.2020)
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Journal Article
Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis
Li, Jian-Yuan, Miklossy, Gabriella, Modukuri, Ram K, Bohren, Kurt M, Yu, Zhifeng, Palaniappan, Murugesan, Faver, John C, Riehle, Kevin, Matzuk, Martin M, Simmons, Nicholas
Published in Bioconjugate chemistry (21.08.2019)
Published in Bioconjugate chemistry (21.08.2019)
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Journal Article
Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice
Depner, Christopher M, Traber, Maret G, Bobe, Gerd, Kensicki, Elizabeth, Bohren, Kurt M, Milne, Ginger, Jump, Donald B, Müller, Michael
Published in PloS one (17.12.2013)
Published in PloS one (17.12.2013)
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Journal Article
A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus
Bohren, Kurt M., Nadkarni, Varsha, Song, Jian H., Gabbay, Kenneth H., Owerbach, David
Published in The Journal of biological chemistry (25.06.2004)
Published in The Journal of biological chemistry (25.06.2004)
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Journal Article
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors
Jimmidi, Ravikumar, Chamakuri, Srinivas, Lu, Shuo, Ucisik, Melek Nihan, Chen, Peng-Jen, Bohren, Kurt M, Moghadasi, Seyed Arad, Versteeg, Leroy, Nnabuife, Christina, Li, Jian-Yuan, Qin, Xuan, Chen, Ying-Chu, Faver, John C, Nyshadham, Pranavanand, Sharma, Kiran L, Sankaran, Banumathi, Judge, Allison, Yu, Zhifeng, Li, Feng, Pollet, Jeroen, Harris, Reuben S, Matzuk, Martin M, Palzkill, Timothy, Young, Damian W
Published in Communications chemistry (04.08.2023)
Published in Communications chemistry (04.08.2023)
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Journal Article
Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library
Dawadi, Surendra, Simmons, Nicholas, Miklossy, Gabriella, Bohren, Kurt M., Faver, John C., Ucisik, Melek Nihan, Nyshadham, Pranavanand, Yu, Zhifeng, Matzuk, Martin M.
Published in Proceedings of the National Academy of Sciences - PNAS (21.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (21.07.2020)
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Journal Article
Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening
Modukuri, Ram K., Monsivais, Diana, Li, Feng, Palaniappan, Murugesan, Bohren, Kurt M., Tan, Zhi, Ku, Angela F., Wang, Yong, Madasu, Chandrashekhar, Li, Jian-Yuan, Tang, Suni, Miklossy, Gabriella, Palmer, Stephen S., Young, Damian W., Matzuk, Martin M.
Published in Journal of medicinal chemistry (09.02.2023)
Published in Journal of medicinal chemistry (09.02.2023)
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Journal Article
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors
Chamakuri, Srinivas, Lu, Shuo, Ucisik, Melek Nihan, Bohren, Kurt M, Chen, Ying-Chu, Du, Huang-Chi, Faver, John C, Jimmidi, Ravikumar, Li, Feng, Li, Jian-Yuan, Nyshadham, Pranavanand, Palmer, Stephen S, Pollet, Jeroen, Qin, Xuan, Ronca, Shannon E, Sankaran, Banumathi, Sharma, Kiran L, Tan, Zhi, Versteeg, Leroy, Yu, Zhifeng, Matzuk, Martin M, Palzkill, Timothy, Young, Damian W
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
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Journal Article
Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology
Madasu, Chandrashekhar, Liao, Zian, Parks, Sydney E, Sharma, Kiran L, Bohren, Kurt M, Ye, Qiuji, Li, Feng, Palaniappan, Murugesan, Tan, Zhi, Yuan, Fei, Creighton, Chad J, Tang, Suni, Masand, Ramya P, Guan, Xiaoming, Young, Damian W, Monsivais, Diana, Matzuk, Martin M
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)
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Journal Article
Ascorbate Synthesis Pathway: DUAL ROLE OF ASCORBATE IN BONE HOMEOSTASIS
Gabbay, Kenneth H, Bohren, Kurt M, Morello, Roy, Bertin, Terry, Liu, Jeff, Vogel, Peter
Published in The Journal of biological chemistry (18.06.2010)
Published in The Journal of biological chemistry (18.06.2010)
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Journal Article
Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries
Monty, Olivier B. C, Nyshadham, Pranavanand, Bohren, Kurt M, Palaniappan, Murugesan, Matzuk, Martin M, Young, Damian W, Simmons, Nicholas
Published in ACS combinatorial science (10.02.2020)
Published in ACS combinatorial science (10.02.2020)
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Journal Article
Reversible male contraception by targeted inhibition of serine/threonine kinase 33
Ku, Angela F., Sharma, Kiran L., Ta, Hai Minh, Sutton, Courtney M., Bohren, Kurt M., Wang, Yong, Chamakuri, Srinivas, Chen, Ruihong, Hakenjos, John M., Jimmidi, Ravikumar, Kent, Katarzyna, Li, Feng, Li, Jian-Yuan, Ma, Lang, Madasu, Chandrashekhar, Palaniappan, Murugesan, Palmer, Stephen S., Qin, Xuan, Robers, Matthew B., Sankaran, Banumathi, Tan, Zhi, Vasquez, Yasmin M., Wang, Jian, Wilkinson, Jennifer, Yu, Zhifeng, Ye, Qiuji, Young, Damian W., Teng, Mingxing, Kim, Choel, Matzuk, Martin M.
Published in Science (American Association for the Advancement of Science) (24.05.2024)
Published in Science (American Association for the Advancement of Science) (24.05.2024)
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Journal Article
1796-P: A-ß+ Ketosis-Prone Diabetes (KPD) Patients Augment Insulin Response to Arginine but Not to Glucose after Sustained Hyperglycemia
HSU, JEAN W., CARDENAS, ADRIANA J., GABA, RUCHI, TOSUR, MUSTAFA, RAM, NALINI, GUTIERREZ, ABSALON D., BOHREN, KURT M., CADUCOY, EUNICE I., JAHOOR, FAROOK, BALASUBRAMANYAM, ASHOK
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
Arginine Metabolism Is Altered in Adults with A-β + Ketosis-Prone Diabetes
Mulukutla, Surya N, Hsu, Jean W, Gaba, Ruchi, Bohren, Kurt M, Guthikonda, Anu, Iyer, Dinakar, Ajami, Nadim J, Petrosino, Joseph F, Hampe, Christiane S, Ram, Nalini, Jahoor, Farook, Balasubramanyam, Ashok
Published in The Journal of nutrition (01.02.2018)
Published in The Journal of nutrition (01.02.2018)
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Journal Article
Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion
Abdillahi, Mariane, Ananthakrishnan, Radha, Vedantham, Srinivasan, Shang, Linshan, Zhu, Zhengbin, Rosario, Rosa, Zirpoli, Hylde, Bohren, Kurt M, Gabbay, Kenneth H, Ramasamy, Ravichandran
Published in American journal of physiology. Heart and circulatory physiology (01.08.2012)
Published in American journal of physiology. Heart and circulatory physiology (01.08.2012)
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Journal Article
Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme
Bohren, Kurt M, Grimshaw, Charles E, Lai, Chung Jeng, Harrison, David H, Ringe, Dagmar, Petsko, Gregory A, Gabbay, Kenneth H
Published in Biochemistry (Easton) (01.03.1994)
Published in Biochemistry (Easton) (01.03.1994)
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Journal Article
Indian women of childbearing age do not metabolically conserve arginine as do American and Jamaican women
Kao, Christina C, Hsu, Jean W, Dwarkanath, Pratibha, Karnes, Jeffrey M, Baker, Tameka M, Bohren, Kurt M, Badaloo, Asha, Thame, Minerva M, Kurpad, Anura V, Jahoor, Farook
Published in The Journal of nutrition (01.05.2015)
Published in The Journal of nutrition (01.05.2015)
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