The vascular endothelial growth factor receptor (VEGFR‐1) supports growth and survival of human breast carcinoma
Wu, Yan, Hooper, Andrea T., Zhong, Zhaojing, Witte, Larry, Bohlen, Peter, Rafii, Shahin, Hicklin, Daniel J.
Published in International journal of cancer (01.10.2006)
Published in International journal of cancer (01.10.2006)
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Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
Carmeliet, Peter, Luttun, Aernout, Tjwa, Marc, Moons, Lieve, Wu, Yan, Angelillo-Scherrer, Anne, Liao, Fang, Nagy, Janice A, Hooper, Andrea, Priller, Josef, De Klerck, Bert, Compernolle, Veerle, Daci, Evis, Bohlen, Peter, Dewerchin, Mieke, Herbert, Jean-Marc, Fava, Roy, Matthys, Patrick, Carmeliet, Geert, Collen, Désiré, Dvorak, Harold F, Hicklin, Daniel J
Published in Nature medicine (01.08.2002)
Published in Nature medicine (01.08.2002)
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Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1 + stem cells from bone-marrow microenvironment
Rafii, Shahin, Hattori, Koichi, Heissig, Beate, Wu, Yan, Dias, Sergio, Tejada, Rafael, Ferris, Barbara, Hicklin, Daniel J, Zhu, Zhenping, Bohlen, Peter, Witte, Larry, Hendrikx, Jan, Hackett, Neil R, Crystal, Ronald G, Moore, Malcolm A.S, Werb, Zena, Lyden, David
Published in Nature medicine (01.08.2002)
Published in Nature medicine (01.08.2002)
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Angiogenesis inhibition by vascular endothelial growth factor receptor-2 blockade reduces stromal matrix metalloproteinase expression, normalizes stromal tissue, and reverts epithelial tumor phenotype in surface heterotransplants
VOSSELER, Silvia, MIRANCEA, Nicolae, BOHLEN, Peter, MUELLER, Margareta M, FUSENIG, Norbert E
Published in Cancer research (Chicago, Ill.) (15.02.2005)
Published in Cancer research (Chicago, Ill.) (15.02.2005)
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A Fully Human Recombinant IgG-like Bispecific Antibody to Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor for Enhanced Antitumor Activity
Lu, Dan, Zhang, Haifan, Koo, Henry, Tonra, James, Balderes, Paul, Prewett, Marie, Corcoran, Eric, Mangalampalli, Venkata, Bassi, Rajiv, Anselma, Deborah, Patel, Dipa, Kang, Xiaoqiang, Ludwig, Dale L., Hicklin, Daniel J., Bohlen, Peter, Witte, Larry, Zhu, Zhenping
Published in The Journal of biological chemistry (20.05.2005)
Published in The Journal of biological chemistry (20.05.2005)
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Differences in Therapeutic Indexes of Combination Metronomic Chemotherapy and an Anti-VEGFR-2 Antibody in Multidrug-resistant Human Breast Cancer Xenografts
KLEMENT, Giannoula, PING HUANG, MAYER, Barbara, GREEN, Shane K, MAN, Shan, BOHLEN, Peter, HICKLIN, Daniel, KERBEL, Robert S
Published in Clinical cancer research (01.01.2002)
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Published in Clinical cancer research (01.01.2002)
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Tailoring in Vitro Selection for a Picomolar Affinity Human Antibody Directed against Vascular Endothelial Growth Factor Receptor 2 for Enhanced Neutralizing Activity
Lu, Dan, Shen, Juqun, Vil, Marie D., Zhang, Haifan, Jimenez, Xenia, Bohlen, Peter, Witte, Larry, Zhu, Zhenping
Published in The Journal of biological chemistry (31.10.2003)
Published in The Journal of biological chemistry (31.10.2003)
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A monoclonal antibody to vascular endothelial–cadherin inhibits tumor angiogenesis without side effects on endothelial permeability
Corada, Monica, Zanetta, Lucia, Orsenigo, Fabrizio, Breviario, Ferruccio, Lampugnani, Maria Grazia, Bernasconi, Sergio, Liao, Fang, Hicklin, Daniel J., Bohlen, Peter, Dejana, Elisabetta
Published in Blood (01.08.2002)
Published in Blood (01.08.2002)
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Inhibition of Both Paracrine and Autocrine VEGF/VEGFR-2 Signaling Pathways is Essential to Induce Long-Term Remission of Xenotransplanted Human Leukemias
Dias, Sergio, Hattori, Koichi, Heissig, Beate, Zhu, Zhenping, Wu, Yan, Witte, Larry, Hicklin, Daniel J., Tateno, Masatoshi, Bohlen, Peter, Malcolm A. S. Moore, Rafii, Shahin
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2001)
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Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy
Lu, Dan, Jimenez, Xenia, Zhang, Haifan, Bohlen, Peter, Witte, Larry, Zhu, Zhenping
Published in International journal of cancer (20.01.2002)
Published in International journal of cancer (20.01.2002)
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Inhibition of Glioblastoma Angiogenesis and Invasion by Combined Treatments Directed Against Vascular Endothelial Growth Factor Receptor-2, Epidermal Growth Factor Receptor, and Vascular Endothelial-Cadherin
LAMSZUS, Katrin, BROCKMANN, Marc A, ECKERICH, Carmen, BOHLEN, Peter, MAY, Chad, MANGOLD, Ulrich, FILLBRANDT, Regina, WESTPHAL, Manfred
Published in Clinical cancer research (01.07.2005)
Published in Clinical cancer research (01.07.2005)
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Simultaneous Blockade of Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor Signaling Pathways in Cancer Cells with a Fully Human Recombinant Bispecific Antibody
Lu, Dan, Zhang, Haifan, Ludwig, Dale, Persaud, Anita, Jimenez, Xenia, Burtrum, Douglas, Balderes, Paul, Liu, Meilin, Bohlen, Peter, Witte, Larry, Zhu, Zhenping
Published in The Journal of biological chemistry (23.01.2004)
Published in The Journal of biological chemistry (23.01.2004)
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Vascular endothelial growth factor receptor 2-mediated angiogenesis is essential for gonadotropin-dependent follicle development
Zimmermann, Ralf C, Hartman, Tipton, Kavic, Suzanne, Pauli, Samuel A, Bohlen, Peter, Sauer, Mark V, Kitajewski, Jan
Published in The Journal of clinical investigation (01.09.2003)
Published in The Journal of clinical investigation (01.09.2003)
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The Vascular Endothelial Growth Factor (VEGF)/VEGF Receptor 2 Pathway Is Critical for Blood Vessel Survival in Corpora Lutea of Pregnancy in the Rodent
Pauli, Samuel A, Tang, Hongyan, Wang, Jeff, Bohlen, Peter, Posser, Robert, Hartman, Tipton, Sauer, Mark V, Kitajewski, Jan, Zimmermann, Ralf C
Published in Endocrinology (Philadelphia) (01.03.2005)
Published in Endocrinology (Philadelphia) (01.03.2005)
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Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis
Li, Yiwen, Wang, Mei-Nai, Li, Hongli, King, Karen D, Bassi, Rajiv, Sun, Haijun, Santiago, Angel, Hooper, Andrea T, Bohlen, Peter, Hicklin, Daniel J
Published in The Journal of experimental medicine (17.06.2002)
Published in The Journal of experimental medicine (17.06.2002)
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Targeting the platelet-derived growth factor receptor α with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications as a potential therapeutic target
Loizos, Nick, Xu, Yan, Huber, Jim, Liu, Meilin, Lu, Dan, Finnerty, Bridget, Rolser, Robin, Malikzay, Asra, Persaud, Anita, Corcoran, Erik, Deevi, Dhanvanthri S, Balderes, Paul, Bassi, Rajiv, Jimenez, Xenia, Joynes, Christopher J, Mangalampalli, Venkata R M, Steiner, Philipp, Tonra, James R, Wu, Yan, Pereira, Daniel S, Zhu, Zhenping, Ludwig, Dale L, Hicklin, Daniel J, Bohlen, Peter, Witte, Larry, Kussie, Paul
Published in Molecular cancer therapeutics (01.03.2005)
Published in Molecular cancer therapeutics (01.03.2005)
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Administration of Antivascular Endothelial Growth Factor Receptor 2 Antibody in the Early Follicular Phase Delays Follicular Selection and Development in the Rhesus Monkey
Zimmermann, Ralf C, Xiao, Ennian, Bohlen, Peter, Ferin, Michel
Published in Endocrinology (Philadelphia) (01.07.2002)
Published in Endocrinology (Philadelphia) (01.07.2002)
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Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells
VINCENT, Loic, JIN, David K, BOHLEN, Peter, NIESVIZKY, Ruben, RAFII, Shahin, KARAJANNIS, Matthias A, SHIDO, Koji, HOOPER, Andrea T, RASHBAUM, William K, PYTOWSKI, Bronislaw, YAN WU, HICKLIN, Daniel J, ZHENPING ZHU
Published in Cancer research (Chicago, Ill.) (15.04.2005)
Published in Cancer research (Chicago, Ill.) (15.04.2005)
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