Phase II Metabolism of Hesperetin by Individual UDP-Glucuronosyltransferases and Sulfotransferases and Rat and Human Tissue Samples
BRAND, Walter, BOERSMA, Marelle G, RIETJENS, Ivonne M. C. M, BIK, Hanneke, HOEK-VAN DEN HIL, Elisabeth F, VERVOORT, Jacques, BARRON, Denis, MEINL, Walter, GLATT, Hansruedi, WILLIAMSON, Gary, VAN BLADEREN, Peter J
Published in Drug metabolism and disposition (01.04.2010)
Published in Drug metabolism and disposition (01.04.2010)
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Journal Article
Regioselectivity of Phase II Metabolism of Luteolin and Quercetin by UDP-Glucuronosyl Transferases
Boersma, Marelle G, van der Woude, Hester, Bogaards, Jan, Boeren, Sjef, Vervoort, Jacques, Cnubben, Nicole H. P, van Iersel, Marlou L. P. S, van Bladeren, Peter J, Rietjens, Ivonne M. C. M
Published in Chemical research in toxicology (20.05.2002)
Published in Chemical research in toxicology (20.05.2002)
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Journal Article
Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes
Jeurissen, Suzanne M. F., Punt, Ans, Boersma, Marelle G., Bogaards, Jan J. P., Fiamegos, Yiannis C., Schilter, Benoit, van Bladeren, Peter J., Cnubben, Nicole H. P., Rietjens, Ivonne M. C. M.
Published in Chemical research in toxicology (01.05.2007)
Published in Chemical research in toxicology (01.05.2007)
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Journal Article
The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids
Rietjens, Ivonne M.C.M., Boersma, Marelle G., Haan, Laura de, Spenkelink, Bert, Awad, Hanem M., Cnubben, Nicole H.P., van Zanden, Jelmer J., Woude, Hester van der, Alink, Gerrit M., Koeman, Jan H.
Published in Environmental toxicology and pharmacology (01.07.2002)
Published in Environmental toxicology and pharmacology (01.07.2002)
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Journal Article
Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin
Wortelboer, Heleen M, Usta, Mustafa, van der Velde, Astrid E, Boersma, Marelle G, Spenkelink, Bert, van Zanden, Jelmer J, Rietjens, Ivonne M. C. M, van Bladeren, Peter J, Cnubben, Nicole H. P
Published in Chemical research in toxicology (01.12.2003)
Published in Chemical research in toxicology (01.12.2003)
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Journal Article
Identification of o-quinone/quinone methide metabolites of quercetin in a cellular in vitro system
Awad, Hanem M., Boersma, Marelle G., Boeren, Sjef, van der Woude, Hester, van Zanden, Jelmer, van Bladeren, Peter J., Vervoort, Jacques, Rietjens, Ivonne M.C.M.
Published in FEBS letters (05.06.2002)
Published in FEBS letters (05.06.2002)
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Journal Article
Differences in simulated liver concentrations of toxic coumarin metabolites in rats and different human populations evaluated through physiologically based biokinetic (PBBK) modeling
Rietjens, Ivonne M.C.M., Boersma, Marelle G., Zaleska, Maria, Punt, Ans
Published in Toxicology in vitro (01.12.2008)
Published in Toxicology in vitro (01.12.2008)
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Journal Article
Human Cytochrome P450 Enzymes of Importance for the Bioactivation of Methyleugenol to the Proximate Carcinogen 1‘-Hydroxymethyleugenol
Jeurissen, Suzanne M. F, Bogaards, Jan J. P, Boersma, Marelle G, ter Horst, Judith P. F, Awad, Hanem M, Fiamegos, Yiannis C, van Beek, Teris A, Alink, Gerrit M, Sudhölter, Ernst J. R, Cnubben, Nicole H. P, Rietjens, Ivonne M. C. M
Published in Chemical research in toxicology (01.01.2006)
Published in Chemical research in toxicology (01.01.2006)
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Journal Article
Regioselectivity and Reversibility of the Glutathione Conjugation of Quercetin Quinone Methide
Boersma, Marelle G, Vervoort, Jacques, Szymusiak, Henryk, Lemanska, Katarzyna, Tyrakowska, Bozena, Cenas, Narimantas, Segura-Aguilar, Juan, Rietjens, Ivonne M. C. M
Published in Chemical research in toxicology (01.03.2000)
Published in Chemical research in toxicology (01.03.2000)
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Journal Article
Human Cytochrome P450 Enzyme Specificity for Bioactivation of Safrole to the Proximate Carcinogen 1‘-Hydroxysafrole
Jeurissen, Suzanne M. F, Bogaards, Jan J. P, Awad, Hanem M, Boersma, Marelle G, Brand, Walter, Fiamegos, Yiannis C, van Beek, Teris A, Alink, Gerrit M, Sudhölter, Ernst J. R, Cnubben, Nicole H. P, Rietjens, Ivonne M. C. M
Published in Chemical research in toxicology (01.09.2004)
Published in Chemical research in toxicology (01.09.2004)
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Journal Article
Quenching of Quercetin Quinone/Quinone Methides by Different Thiolate Scavengers: Stability and Reversibility of Conjugate Formation
Awad, Hanem M, Boersma, Marelle G, Boeren, Sjef, van Bladeren, Peter J, Vervoort, Jacques, Rietjens, Ivonne M. C. M
Published in Chemical research in toxicology (01.07.2003)
Published in Chemical research in toxicology (01.07.2003)
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Journal Article
Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats
Punt, Ans, Paini, Alicia, Boersma, Marelle G., Freidig, Andreas P., Delatour, Thierry, Scholz, Gabriele, Schilter, Benoît, Bladeren, Peter J. van, Rietjens, Ivonne M. C. M.
Published in Toxicological sciences (01.08.2009)
Published in Toxicological sciences (01.08.2009)
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Journal Article
Identification of 14 Quercetin Phase II Mono- and Mixed Conjugates and Their Formation by Rat and Human Phase II in Vitro Model Systems
van der Woude, Hester, Boersma, Marelle G, Vervoort, Jacques, Rietjens, Ivonne M. C. M
Published in Chemical research in toxicology (01.11.2004)
Published in Chemical research in toxicology (01.11.2004)
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Journal Article
Physiologically based biokinetic (PBBK) modeling of safrole bioactivation and detoxification in humans as compared with rats
Martati, Erryana, Boersma, Marelle G, Spenkelink, Albertus, Khadka, Dambar B, van Bladeren, Peter J, Rietjens, Ivonne M C M, Punt, Ans
Published in Toxicological sciences (01.08.2012)
Published in Toxicological sciences (01.08.2012)
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Journal Article
Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat
Al-Subeihi, Ala' A.A., Spenkelink, Bert, Punt, Ans, Boersma, Marelle G., van Bladeren, Peter J., Rietjens, Ivonne M.C.M.
Published in Toxicology and applied pharmacology (01.05.2012)
Published in Toxicology and applied pharmacology (01.05.2012)
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Journal Article
A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat
Punt, Ans, Freidig, Andreas P., Delatour, Thierry, Scholz, Gabriele, Boersma, Marelle G., Schilter, Benoît, van Bladeren, Peter J., Rietjens, Ivonne M.C.M.
Published in Toxicology and applied pharmacology (01.09.2008)
Published in Toxicology and applied pharmacology (01.09.2008)
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Journal Article
Conversion of 2-Fluoromuconate to cis-Dienelactone by Purified Enzymes of Rhodococcus opacus 1cp
Solyanikova, Inna P, Moiseeva, Olga V, Boeren, Sjef, Boersma, Marelle G, Kolomytseva, Marina P, Vervoort, Jacques, Rietjens, Ivonne M C M, Golovleva, Ludmila A, van Berkel, Willem J H
Published in Applied and Environmental Microbiology (01.09.2003)
Published in Applied and Environmental Microbiology (01.09.2003)
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Journal Article
Safety evaluation of neem ( Azadirachta indica) derived pesticides
Boeke, Sara J, Boersma, Marelle G, Alink, Gerrit M, van Loon, Joop J.A, van Huis, Arnold, Dicke, Marcel, Rietjens, Ivonne M.C.M
Published in Journal of Ethnopharmacology (01.09.2004)
Published in Journal of Ethnopharmacology (01.09.2004)
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Journal Article
Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat
Al-Subeihi, Ala′ A.A., Spenkelink, Bert, Rachmawati, Novalia, Boersma, Marelle G., Punt, Ans, Vervoort, Jacques, van Bladeren, Peter J., Rietjens, Ivonne M.C.M.
Published in Toxicology in vitro (01.02.2011)
Published in Toxicology in vitro (01.02.2011)
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Journal Article