Recently reported biological activities of pyrazole compounds
Faria, Jéssica Venância, Vegi, Percilene Fazolin, Miguita, Ana Gabriella Carvalho, dos Santos, Maurício Silva, Boechat, Nubia, Bernardino, Alice Maria Rolim
Published in Bioorganic & medicinal chemistry (01.11.2017)
Published in Bioorganic & medicinal chemistry (01.11.2017)
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New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells
Oliveira, Andressa, Moura, Stefany, Pimentel, Luiz, Neto, João, Dantas, Rafael, Silva-Jr, Floriano, Bastos, Monica, Boechat, Nubia
Published in Molecules (Basel, Switzerland) (24.01.2022)
Published in Molecules (Basel, Switzerland) (24.01.2022)
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Pyrroles as Privileged Scaffolds in the Search for New Potential HIV Inhibitors
Bianco, Maria da Conceição Avelino Dias, Marinho, Debora Inacio Leite Firmino, Hoelz, Lucas Villas Boas, Bastos, Monica Macedo, Boechat, Nubia
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Published in Pharmaceuticals (Basel, Switzerland) (02.09.2021)
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Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors
Azeredo, Luís Felipe S.P., Coutinho, Julia P., Jabor, Valquiria A.P., Feliciano, Patricia R., Nonato, Maria Cristina, Kaiser, Carlos R., Menezes, Carla Maria S., Hammes, Amanda S.O., Caffarena, Ernesto Raul, Hoelz, Lucas V.B., de Souza, Nicolli B., Pereira, Glaécia A.N., Cerávolo, Isabela P., Krettli, Antoniana U., Boechat, Nubia
Published in European journal of medicinal chemistry (27.01.2017)
Published in European journal of medicinal chemistry (27.01.2017)
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The Use of Zidovudine Pharmacophore in Multi-Target-Directed Ligands for AIDS Therapy
Bianco, Maria da Conceição Avelino Dias, Inacio Leite, Debora, Silva Castelo Branco, Frederico, Boechat, Nubia, Uliassi, Elisa, Bolognesi, Maria Laura, Bastos, Monica Macedo
Published in Molecules (Basel, Switzerland) (01.12.2022)
Published in Molecules (Basel, Switzerland) (01.12.2022)
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New hybrid trifluoromethylquinolines as antiplasmodium agents
da Silva, Renata M.R.J., Gandi, Marilia O., Mendonça, Jorge S., Carvalho, Alcione S., Coutinho, Julia Penna, Aguiar, Anna C.C., Krettli, Antoniana U., Boechat, Nubia
Published in Bioorganic & medicinal chemistry (15.03.2019)
Published in Bioorganic & medicinal chemistry (15.03.2019)
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New Compounds Hybrids 1H-1,2,3-Triazole-Quinoline Against Plasmodium falciparum
Boechat, Núbia, Ferreira, Maria de Lourdes G., Pinheiro, Luiz C. S., Jesus, Antônio M. L., Leite, Milene M. M., Júnior, Carlos C. S., Aguiar, Anna C. C., de Andrade, Isabel M., Krettli, Antoniana U.
Published in Chemical biology & drug design (01.09.2014)
Published in Chemical biology & drug design (01.09.2014)
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A Review of the Development of Multitarget Molecules against HIV-TB Coinfection Pathogens
Leite, Debora Inacio, de Castro Bazan Moura, Stefany, da Conceição Avelino Dias, Maria, Costa, Carolina Catta Preta, Machado, Gustavo Peixoto, Pimentel, Luiz Claudio Ferreira, Branco, Frederico Silva Castelo, Moreira, Rui, Bastos, Monica Macedo, Boechat, Nubia
Published in Molecules (Basel, Switzerland) (01.04.2023)
Published in Molecules (Basel, Switzerland) (01.04.2023)
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Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives
Costa, Marilia S., Boechat, Núbia, Rangel, Érica A., da Silva, Fernando de C., de Souza, Alessandra M.T., Rodrigues, Carlos R., Castro, Helena C., Junior, Ivan N., Lourenço, Maria Cristina S., Wardell, Solange M.S.V., Ferreira, Vitor F.
Published in Bioorganic & medicinal chemistry (15.12.2006)
Published in Bioorganic & medicinal chemistry (15.12.2006)
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Novel 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivatives: a patent review (2008 - 2011)
Ferreira, Vitor F, da Rocha, David R, da Silva, Fernando C, Ferreira, Patrícia G, Boechat, Núbia A, Magalhães, Jorge L
Published in Expert opinion on therapeutic patents (01.03.2013)
Published in Expert opinion on therapeutic patents (01.03.2013)
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Ponatinib: A Review of the History of Medicinal Chemistry behind Its Development
Nascimento, Mayara, Moura, Stefany, Parra, Lidia, Vasconcellos, Valeska, Costa, Gabriela, Leite, Debora, Dias, Maria, Fernandes, Tácio Vinício Amorim, Hoelz, Lucas, Pimentel, Luiz, Bastos, Monica, Boechat, Nubia
Published in Pharmaceuticals (Basel, Switzerland) (11.10.2024)
Published in Pharmaceuticals (Basel, Switzerland) (11.10.2024)
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Study of the dynamic behavior of the cruzain enzyme in free and complexed forms with competitive and noncovalent benzimidazole inhibitors
Reis, Caroline Rodrigues Chaves dos, Souza, Hellen Valério Chaves Moura de, Leme, Rennan Papaleo Paes, Castelo-Branco, Frederico Silva, Fernandes, Tácio Vinício Amorim, Boechat, Núbia, Dias, Luiza Rosaria Sousa, Hoelz, Lucas Villas Bôas
Published in Journal of biomolecular structure & dynamics (03.07.2023)
Published in Journal of biomolecular structure & dynamics (03.07.2023)
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Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs
de Lourdes G. Ferreira, Maria, Pinheiro, Luiz C. S., Santos-Filho, Osvaldo A., Peçanha, Marta D. S., Sacramento, Carolina Q., Machado, Viviane, Ferreira, Vitor F., Souza, Thiago Moreno L., Boechat, Núbia
Published in Medicinal chemistry research (01.03.2014)
Published in Medicinal chemistry research (01.03.2014)
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The Medicinal Chemistry of 3-nitro-1,2,4-triazoles: Focus on Infectious Diseases
França, Rodolfo Rodrigo Florido, Menozzi, Cheyene Almeida Celestino, Castelo-Branco, Frederico Silva, Hoelz, Lucas Villas Bôas, Boechat, Nubia
Published in Current topics in medicinal chemistry (01.01.2021)
Published in Current topics in medicinal chemistry (01.01.2021)
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Journal Article
In vitro genotoxicity of nitroimidazoles as a tool in the search of new trypanocidal agents
Von Trompowsky, Ana Claudia Manoel, Conde, Taline Ramos, Lemos, Renata Calil, Quaresma, Bruna Maria Cs, Pitombeira, Marcelly Cristina Sr, de Carvalho, Alcione Silva, Boechat, Núbia, Salomão, Kelly, de Castro, Solange Lisboa, Zamith, Helena Pereira da Silva
Published in Memórias do Instituto Oswaldo Cruz (01.01.2019)
Published in Memórias do Instituto Oswaldo Cruz (01.01.2019)
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Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and Mefloquine
Penna-Coutinho, Julia, Almela, Maria Jesús, Miguel-Blanco, Celia, Herreros, Esperanza, Sá, Paula M, Boechat, Núbia, Krettli, Antoniana Ursine
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
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Anti-Trypanosoma cruzi Activity, Mutagenicity, Hepatocytotoxicity and Nitroreductase Enzyme Evaluation of 3-Nitrotriazole, 2-Nitroimidazole and Triazole Derivatives
Menozzi, Cheyene Almeida Celestino, França, Rodolfo Rodrigo Florido, Luccas, Pedro Henrique, Baptista, Mayara dos Santos, Fernandes, Tácio Vinício Amorim, Hoelz, Lucas Villas Bôas, Sales Junior, Policarpo Ademar, Murta, Silvane Maria Fonseca, Romanha, Alvaro, Galvão, Bárbara Verena Dias, Macedo, Marcela de Oliveira, Goldstein, Alana da Cunha, Araujo-Lima, Carlos Fernando, Felzenszwalb, Israel, Nonato, Maria Cristina, Castelo-Branco, Frederico Silva, Boechat, Nubia
Published in Molecules (Basel, Switzerland) (01.11.2023)
Published in Molecules (Basel, Switzerland) (01.11.2023)
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Journal Article
Studies of genotoxicity and mutagenicity of nitroimidazoles: demystifying this critical relationship with the nitro group
Boechat, Núbia, Carvalho, Alcione S, Salomão, Kelly, Castro, Solange L de, Araujo-Lima, Carlos F, Mello, Francisco V C, Felzenszwalb, Israel, Aiub, Claudia A F, Conde, Taline Ramos, Zamith, Helena P S, Skupin, Rolf, Haufe, Günter
Published in Memórias do Instituto Oswaldo Cruz (01.06.2015)
Published in Memórias do Instituto Oswaldo Cruz (01.06.2015)
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(Phenylamino)pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia
Pimentel, Luiz Claudio Ferreira, Hoelz, Lucas Villas Boas, Canzian, Henayle Fernandes, Branco, Frederico Silva Castelo, de Oliveira, Andressa Paula, Campos, Vinicius Rangel, Júnior, Floriano Paes Silva, Dantas, Rafael Ferreira, Resende, Jackson Antônio Lamounier Camargos, Cunha, Anna Claudia, Boechat, Nubia, Bastos, Mônica Macedo
Published in Beilstein journal of organic chemistry (01.09.2021)
Published in Beilstein journal of organic chemistry (01.09.2021)
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