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Published in PloS one (24.10.2011)
Published in PloS one (24.10.2011)
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PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models
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Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Development of High-Throughput TR-FRET and AlphaScreen® Assays for Identification of Potent Inhibitors of PDK1
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Published in Journal of biomolecular screening (01.12.2009)
Published in Journal of biomolecular screening (01.12.2009)
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Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme
Li, Yi-Jia, Du, Li, Wang, Jianghai, Vega, Ramir, Lee, Terry D, Miao, Yunan, Aldana-Masangkay, Grace, Samuels, Eric R, Li, Baozong, Ouyang, S Xiaohu, Colayco, Sharon A, Bobkova, Ekaterina V, Divlianska, Daniela B, Sergienko, Eduard, Chung, Thomas D Y, Fakih, Marwan, Chen, Yuan
Published in Cell chemical biology (21.02.2019)
Published in Cell chemical biology (21.02.2019)
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Catalytic Properties of Mutant 23 S Ribosomes Resistant to Oxazolidinones
Bobkova, Ekaterina V, Yan, Yong Ping, Jordan, Douglas B, Kurilla, Michael G, Pompliano, David L
Published in The Journal of biological chemistry (14.03.2003)
Published in The Journal of biological chemistry (14.03.2003)
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Dual-Specificity Phosphatase 3 Deficiency or Inhibition Limits Platelet Activation and Arterial Thrombosis
Musumeci, Lucia, Kuijpers, Marijke J, Gilio, Karen, Hego, Alexandre, Théâtre, Emilie, Maurissen, Lisbeth, Vandereyken, Maud, Diogo, Catia V, Lecut, Christelle, Guilmain, William, Bobkova, Ekaterina V, Eble, Johannes A, Dahl, Russell, Drion, Pierre, Rascon, Justin, Mostofi, Yalda, Yuan, Hongbin, Sergienko, Eduard, Chung, Thomas D.Y, Thiry, Marc, Senis, Yotis, Moutschen, Michel, Mustelin, Tomas, Lancellotti, Patrizio, Heemskerk, Johan W.M, Tautz, Lutz, Oury, Cécile, Rahmouni, Souad
Published in Circulation (New York, N.Y.) (17.02.2015)
Published in Circulation (New York, N.Y.) (17.02.2015)
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Identification of Novel Inhibitors of Bacterial Translation Elongation Factors
JAYASEKERA, Maithri M. K, ONHEIBER, Keysha, DELCAMP, Tavner, SHAOMING HUANG, WOLIN, Ronald, BOBKOVA, Ekaterina V, SHAW, Karen Joy, KEITH, John, VENKATESAN, Hariharan, SANTILLAN, Alejandro, STOCKING, Emily M, LIU TANG, MILLER, Jennifer, GOMEZ, Leslie, RHEAD, Brooke
Published in Antimicrobial Agents and Chemotherapy (01.01.2005)
Published in Antimicrobial Agents and Chemotherapy (01.01.2005)
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Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism of Action by Ultrahigh Throughput Screening
Bobkova, Ekaterina V., Weber, Michael J., Xu, Zangwei, Zhang, Yan-Ling, Jung, Joon, Blume-Jensen, Peter, Northrup, Alan, Kunapuli, Priya, Andersen, Jannik N., Kariv, Ilona
Published in The Journal of biological chemistry (11.06.2010)
Published in The Journal of biological chemistry (11.06.2010)
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Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR
Nagashima, Kumiko, Shumway, Stuart D, Sathyanarayanan, Sriram, Chen, Albert H, Dolinski, Brian, Xu, Youyuan, Keilhack, Heike, Nguyen, Thi, Wiznerowicz, Maciej, Li, Lixia, Lutterbach, Bart A, Chi, An, Paweletz, Cloud, Allison, Timothy, Yan, Youwei, Munshi, Sanjeev K, Klippel, Anke, Kraus, Manfred, Bobkova, Ekaterina V, Deshmukh, Sujal, Xu, Zangwei, Mueller, Uwe, Szewczak, Alexander A, Pan, Bo-Sheng, Richon, Victoria, Pollock, Roy, Blume-Jensen, Peter, Northrup, Alan, Andersen, Jannik N
Published in The Journal of biological chemistry (25.02.2011)
Published in The Journal of biological chemistry (25.02.2011)
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Inhibition of Hematopoietic Protein Tyrosine Phosphatase Augments and Prolongs ERK1/2 and p38 Activation
Sergienko, Eduard, Xu, Jian, Liu, Wallace H, Dahl, Russell, Critton, David A, Su, Ying, Brown, Brock T, Chan, Xochella, Yang, Li, Bobkova, Ekaterina V, Vasile, Stefan, Yuan, Hongbin, Rascon, Justin, Colayco, Sharon, Sidique, Shyama, Cosford, Nicholas D. P, Chung, Thomas D. Y, Mustelin, Tomas, Page, Rebecca, Lombroso, Paul J, Tautz, Lutz
Published in ACS chemical biology (17.02.2012)
Published in ACS chemical biology (17.02.2012)
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Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes
Ardecky, Robert J., Bobkova, Ekaterina V., Kiffer-Moreira, Tina, Brown, Brock, Ganji, Santhi, Zou, Jiwen, Pass, Ian, Narisawa, Sonoko, Iano, Flávia Godoy, Rosenstein, Craig, Cheltsov, Anton, Rascon, Justin, Hedrick, Michael, Gasior, Carlton, Forster, Anita, Shi, Shenghua, Dahl, Russell, Vasile, Stefan, Su, Ying, Sergienko, Eduard, Chung, Thomas D.Y., Kaunitz, Jonathan, Hoylaerts, Marc F., Pinkerton, Anthony B., Millán, José Luis
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids
Bobkova, Ekaterina V, Liu, Wallace H, Colayco, Sharon, Rascon, Justin, Vasile, Stefan, Gasior, Carlton, Critton, David A, Chan, Xochella, Dahl, Russell, Su, Ying, Sergienko, Eduard, Chung, Thomas D. Y, Mustelin, Tomas, Page, Rebecca, Tautz, Lutz
Published in ACS medicinal chemistry letters (10.02.2011)
Published in ACS medicinal chemistry letters (10.02.2011)
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Oxazolidinones Mechanism of Action: Inhibition of the First Peptide Bond Formation
Patel, Utpal, Yan, Yong P., Hobbs, Frank W., Kaczmarczyk, Janet, Slee, Andrew M., Pompliano, David L., Kurilla, Michael G., Bobkova, Ekaterina V.
Published in The Journal of biological chemistry (05.10.2001)
Published in The Journal of biological chemistry (05.10.2001)
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Modulators of intestinal alkaline phosphatase
Bobkova, Ekaterina V, Kiffer-Moreira, Tina, Sergienko, Eduard A
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2013)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2013)
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Mutational Analysis of the Hydrolytic Activity of Yeast RNA Polymerase III
Bobkova, Ekaterina V., Habib, Natasha, Alexander, Gemma, Hall, Benjamin D.
Published in The Journal of biological chemistry (23.07.1999)
Published in The Journal of biological chemistry (23.07.1999)
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Substrate Specificity of the RNase Activity of Yeast RNA Polymerase III
Bobkova, Ekaterina V., Hall, Benjamin D.
Published in The Journal of biological chemistry (05.09.1997)
Published in The Journal of biological chemistry (05.09.1997)
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Identification of inhibitors of bacterial transcription/translation machinery utilizing a miniaturized 1536-well format screen
Kariv, I, Cao, H, Marvil, P D, Bobkova, E V, Bukhtiyarov, Y E, Yan, Y P, Patel, U, Coudurier, L, Chung, T D, Oldenburg, K R
Published in Journal of biomolecular screening (01.08.2001)
Published in Journal of biomolecular screening (01.08.2001)
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DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis
Musumeci, Lucia, Kuijpers, Marijke, Gilio, Karen, Hego, Alexandre, Theatre, Emilie, Maurissen, Lisbeth, Vandereyken, Maud, Diogo, Catia, LECUT, Christelle, Guilmain, William, Bobkova, Ekaterina, Eble, Johannes, Dahl, Russell, Drion, Pierre, Rascon, Justin, Mostofi, Yalda, Yuan, Hongbin, Sergienko, Eduard, Chung, Thomas, Thiry, Marc, Senis, Yotis, MOUTSCHEN, Michel, Mustelin, Tomas, Lancellotti, Patrizio, Heemskerk, Johan, Tautz, Lutz, Oury, Cécile, Rahmouni, Souad
Published in Circulation (New York, N.Y.) (17.02.2015)
Published in Circulation (New York, N.Y.) (17.02.2015)
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Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells
Nagashima, Kumiko, Shumway, Stuart D., Sathyanarayanan, Sriram, Chen, Albert H., Dolinski, Brian, Xu, Youyuan, Keilhack, Heike, Nguyen, Thi, Wiznerowicz, Maciej, Li, Lixia, Lutterbach, Bart A., Chi, An, Paweletz, Cloud, Allison, Timothy, Yan, Youwei, Munshi, Sanjeev K., Klippel, Anke, Kraus, Manfred, Bobkova, Ekaterina V., Deshmukh, Sujal, Xu, Zangwei, Mueller, Uwe, Szewczak, Alexander A., Pan, Bo-Sheng, Richon, Victoria, Pollock, Roy, Blume-Jensen, Peter, Northrup, Alan, Andersen, Jannik N.
Published in The Journal of biological chemistry (25.02.2011)
Published in The Journal of biological chemistry (25.02.2011)
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Journal Article
I PDK1 Attenuation Fails to Prevent Tumor Formation in PTEN-Deficient Transgenic Mouse Models
ELLWOOD-YEN, Katharine, KEILHACK, Heike, GARGANO, Diana, SHOMER, Nirah H, ANGAGAW, Minilik, LECCESE, Erica, ANDRADE, Paula, HURD, Melissa, SHIN, Myung K, VOGT, Thomas F, NORTHRUP, Alan, BOBKOVA, Ekaterina V, KUNII, Kaiko, KASIBHATLA, Shailaja, BRONSON, Roderick T, SCOTT, Martin L, DRAETTA, Giulio, RICHON, Victoria, KOHL, Nancy, BLUME-JENSEN, Peter, ANDERSEN, Jannik N, KRAUS, Manfred, DOLINSKI, Brian, CONNOR, Yamicia, KUN HU, NAGASHIMA, Kumiko, O'HARE, Erin, ERKUL, Yusuf, DI BACCO, Alessandra
Published in Cancer research (Chicago, Ill.) (2011)
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Published in Cancer research (Chicago, Ill.) (2011)
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