A human coronavirus evolves antigenically to escape antibody immunity
Eguia, Rachel T, Crawford, Katharine H D, Stevens-Ayers, Terry, Kelnhofer-Millevolte, Laurel, Greninger, Alexander L, Englund, Janet A, Boeckh, Michael J, Bloom, Jesse D
Published in PLoS pathogens (08.04.2021)
Published in PLoS pathogens (08.04.2021)
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Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding
Starr, Tyler N., Greaney, Allison J., Hilton, Sarah K., Ellis, Daniel, Crawford, Katharine H.D., Dingens, Adam S., Navarro, Mary Jane, Bowen, John E., Tortorici, M. Alejandra, Walls, Alexandra C., King, Neil P., Veesler, David, Bloom, Jesse D.
Published in Cell (03.09.2020)
Published in Cell (03.09.2020)
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In the light of directed evolution: Pathways of adaptive protein evolution
Bloom, Jesse D, Arnold, Frances H
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
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Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains
Starr, Tyler N, Greaney, Allison J, Stewart, Cameron M, Walls, Alexandra C, Hannon, William W, Veesler, David, Bloom, Jesse D
Published in PLoS pathogens (18.11.2022)
Published in PLoS pathogens (18.11.2022)
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Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Crawford, Katharine H D, Dingens, Adam S, Eguia, Rachel, Wolf, Caitlin R, Wilcox, Naomi, Logue, Jennifer K, Shuey, Kiel, Casto, Amanda M, Fiala, Brooke, Wrenn, Samuel, Pettie, Deleah, King, Neil P, Greninger, Alexander L, Chu, Helen Y, Bloom, Jesse D
Published in The Journal of infectious diseases (03.02.2021)
Published in The Journal of infectious diseases (03.02.2021)
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Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
Greaney, Allison J., Starr, Tyler N., Barnes, Christopher O., Weisblum, Yiska, Schmidt, Fabian, Caskey, Marina, Gaebler, Christian, Cho, Alice, Agudelo, Marianna, Finkin, Shlomo, Wang, Zijun, Poston, Daniel, Muecksch, Frauke, Hatziioannou, Theodora, Bieniasz, Paul D., Robbiani, Davide F., Nussenzweig, Michel C., Bjorkman, Pamela J., Bloom, Jesse D.
Published in Nature communications (07.07.2021)
Published in Nature communications (07.07.2021)
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Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants
Lee, Juhye M., Huddleston, John, Doud, Michael B., Hooper, Kathryn A., Wu, Nicholas C., Bedford, Trevor, Bloom, Jesse D.
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2018)
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