Beyond intestinal soap—bile acids in metabolic control
Kuipers, Folkert, Bloks, Vincent W., Groen, Albert K.
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Published in Nature reviews. Endocrinology (01.08.2014)
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In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation
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A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]
de Boer, Jan Freark, Verkade, Esther, Mulder, Niels L., de Vries, Hilde D., Huijkman, Nicolette, Koehorst, Martijn, Boer, Theo, Wolters, Justina C., Bloks, Vincent W., van de Sluis, Bart, Kuipers, Folkert
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Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a
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Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice
Schonewille, Marleen, Freark de Boer, Jan, Mele, Laura, Wolters, Henk, Bloks, Vincent W., Wolters, Justina C., Kuivenhoven, Jan A., Tietge, Uwe J.F., Brufau, Gemma, Groen, Albert K.
Published in Journal of lipid research (01.08.2016)
Published in Journal of lipid research (01.08.2016)
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Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction
van Zutphen, Tim, Ciapaite, Jolita, Bloks, Vincent W, Ackereley, Cameron, Gerding, Albert, Jurdzinski, Angelika, de Moraes, Roberta Allgayer, Zhang, Ling, Wolters, Justina C, Bischoff, Rainer, Wanders, Ronald J, Houten, Sander M, Bronte-Tinkew, Dana, Shatseva, Tatiana, Lewis, Gary F, Groen, Albert K, Reijngoud, Dirk-Jan, Bakker, Barbara M, Jonker, Johan W, Kim, Peter K, Bandsma, Robert H.J
Published in Journal of hepatology (01.12.2016)
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Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion
Jakulj, Lily, van Dijk, Theo H., de Boer, Jan Freark, Kootte, Ruud S., Schonewille, Marleen, Paalvast, Yared, Boer, Theo, Bloks, Vincent W., Boverhof, Renze, Nieuwdorp, Max, Beuers, Ulrich H.W., Stroes, Erik S.G., Groen, Albert K.
Published in Cell metabolism (13.12.2016)
Published in Cell metabolism (13.12.2016)
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Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome
Vrieze, Anne, Van Nood, Els, Holleman, Frits, Salojärvi, Jarkko, Kootte, Ruud S, Bartelsman, Joep F.W.M, Dallinga–Thie, Geesje M, Ackermans, Mariette T, Serlie, Mireille J, Oozeer, Raish, Derrien, Muriel, Druesne, Anne, Van Hylckama Vlieg, Johan E.T, Bloks, Vincent W, Groen, Albert K, Heilig, Hans G.H.J, Zoetendal, Erwin G, Stroes, Erik S, de Vos, Willem M, Hoekstra, Joost B.L, Nieuwdorp, Max
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2012)
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Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content
Chen, Lianmin, van den Munckhof, Inge C.L., Schraa, Kiki, ter Horst, Rob, Koehorst, Martijn, van Faassen, Martijn, van der Ley, Claude, Doestzada, Marwah, Zhernakova, Daria V., Kurilshikov, Alexander, Bloks, Vincent W., Groen, Albert K., Riksen, Niels P., Rutten, Joost H.W., Joosten, Leo A.B., Wijmenga, Cisca, Zhernakova, Alexandra, Netea, Mihai G., Fu, Jingyuan, Kuipers, Folkert
Published in Cell reports (Cambridge) (06.10.2020)
Published in Cell reports (Cambridge) (06.10.2020)
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Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism
Brufau, Gemma, Stellaard, Frans, Prado, Kris, Bloks, Vincent W., Jonkers, Elles, Boverhof, Renze, Kuipers, Folkert, Murphy, Elizabeth J.
Published in Hepatology (Baltimore, Md.) (01.10.2010)
Published in Hepatology (Baltimore, Md.) (01.10.2010)
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Characterization of gut microbial structural variations as determinants of human bile acid metabolism
Wang, Daoming, Doestzada, Marwah, Chen, Lianmin, Andreu-Sánchez, Sergio, van den Munckhof, Inge C.L., Augustijn, Hannah E., Koehorst, Martijn, Ruiz-Moreno, Angel J., Bloks, Vincent W., Riksen, Niels P., Rutten, Joost H.W., Joosten, Leo A.B., Netea, Mihai G., Wijmenga, Cisca, Zhernakova, Alexandra, Kuipers, Folkert, Fu, Jingyuan
Published in Cell host & microbe (08.12.2021)
Published in Cell host & microbe (08.12.2021)
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Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion
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Published in Hepatology (Baltimore, Md.) (01.11.2023)
Published in Hepatology (Baltimore, Md.) (01.11.2023)
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Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice
Boesjes, Marije, Bloks, Vincent W, Hageman, Jurre, Bos, Trijnie, van Dijk, Theo H, Havinga, Rick, Wolters, Henk, Jonker, Johan W, Kuipers, Folkert, Groen, Albert K
Published in PloS one (15.12.2014)
Published in PloS one (15.12.2014)
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Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice
de Boer, Jan Freark, Schonewille, Marleen, Boesjes, Marije, Wolters, Henk, Bloks, Vincent W, Bos, Trijnie, van Dijk, Theo H, Jurdzinski, Angelika, Boverhof, Renze, Wolters, Justina C, Kuivenhoven, Jan A, van Deursen, Jan M, Oude Elferink, Ronald P.J, Moschetta, Antonio, Kremoser, Claus, Verkade, Henkjan J, Kuipers, Folkert, Groen, Albert K
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
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Glucose‐6‐Phosphate Regulates Hepatic Bile Acid Synthesis in Mice
Hoogerland, Joanne A., Lei, Yu, Wolters, Justina C., Boer, Jan Freark, Bos, Trijnie, Bleeker, Aycha, Mulder, Niels L., Dijk, Theo H., Kuivenhoven, Jan A., Rajas, Fabienne, Mithieux, Gilles, Haeusler, Rebecca A., Verkade, Henkjan J., Bloks, Vincent W., Kuipers, Folkert, Oosterveer, Maaike H.
Published in Hepatology (Baltimore, Md.) (01.12.2019)
Published in Hepatology (Baltimore, Md.) (01.12.2019)
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Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet
Ronda, Onne A. H. O, van de Heijning, Bert J. M, de Bruin, Alain, Thomas, Rachel E, Martini, Ingrid, Koehorst, Martijn, Gerding, Albert, Koster, Mirjam H, Bloks, Vincent W, Jurdzinski, Angelika, Mulder, Niels L, Havinga, Rick, van der Beek, Eline M, Reijngoud, Dirk-Jan, Kuipers, Folkert, Verkade, Henkjan J, Greene, Michael W
Published in PloS one (21.09.2020)
Published in PloS one (21.09.2020)
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An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors
Lu, Xueling, Fraszczyk, Eliza, van der Meer, Thomas P., van Faassen, Martijn, Bloks, Vincent W., Kema, Ido P., van Beek, André P., Li, Shuang, Franke, Lude, Westra, Harm-Jan, Xu, Xijin, Huo, Xia, Snieder, Harold, Wolffenbuttel, Bruce H.R., van Vliet-Ostaptchouk, Jana V.
Published in Environment international (01.11.2020)
Published in Environment international (01.11.2020)
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Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts
Fraszczyk, Eliza, Spijkerman, Annemieke M. W., Zhang, Yan, Brandmaier, Stefan, Day, Felix R., Zhou, Li, Wackers, Paul, Dollé, Martijn E. T., Bloks, Vincent W., Gào, Xīn, Gieger, Christian, Kooner, Jaspal, Kriebel, Jennifer, Picavet, H. Susan J., Rathmann, Wolfgang, Schöttker, Ben, Loh, Marie, Verschuren, W. M. Monique, van Vliet-Ostaptchouk, Jana V., Wareham, Nicholas J., Chambers, John C., Ong, Ken K., Grallert, Harald, Brenner, Hermann, Luijten, Mirjam, Snieder, Harold
Published in Diabetologia (01.05.2022)
Published in Diabetologia (01.05.2022)
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Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70 -/- mice
de Vries, Hilde D, Eijgenraam, Tim R, Bloks, Vincent W, Mulder, Niels L, van Zutphen, Tim, Silljé, Herman H W, Kuipers, Folkert, de Boer, Jan Freark
Published in Pediatric research (02.10.2024)
Published in Pediatric research (02.10.2024)
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