Recent advances in the molecular understanding of glioblastoma
Bleeker, Fonnet E., Molenaar, Remco J., Leenstra, Sieger
Published in Journal of neuro-oncology (01.05.2012)
Published in Journal of neuro-oncology (01.05.2012)
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The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation
Molenaar, Remco J., Radivoyevitch, Tomas, Maciejewski, Jaroslaw P., van Noorden, Cornelis J.F., Bleeker, Fonnet E.
Published in Biochimica et biophysica acta (01.12.2014)
Published in Biochimica et biophysica acta (01.12.2014)
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Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
Molenaar, Remco J, Botman, Dennis, Smits, Myrthe A, Hira, Vashendriya V, van Lith, Sanne A, Stap, Jan, Henneman, Peter, Khurshed, Mohammed, Lenting, Krissie, Mul, Adri N, Dimitrakopoulou, Dionysia, van Drunen, Cornelis M, Hoebe, Ron A, Radivoyevitch, Tomas, Wilmink, Johanna W, Maciejewski, Jaroslaw P, Vandertop, W Peter, Leenders, William P, Bleeker, Fonnet E, van Noorden, Cornelis J
Published in Cancer research (Chicago, Ill.) (15.11.2015)
Published in Cancer research (Chicago, Ill.) (15.11.2015)
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The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone
Molenaar, Remco J, Verbaan, Dagmar, Lamba, Simona, Zanon, Carlo, Jeuken, Judith W M, Boots-Sprenger, Sandra H E, Wesseling, Pieter, Hulsebos, Theo J M, Troost, Dirk, van Tilborg, Angela A, Leenstra, Sieger, Vandertop, W Peter, Bardelli, Alberto, van Noorden, Cornelis J F, Bleeker, Fonnet E
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2014)
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Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma
BALAKRISHNAN, Asha, BLEEKER, Fonnet E, LAMBA, Simona, RODOLFO, Monica, DANIOTTI, Maria, SCARPA, Aldo, VAN TILBORG, Angela A, LEENSTRA, Sieger, ZANON, Carlo, BARDELLI, Alberto
Published in Cancer research (Chicago, Ill.) (15.04.2007)
Published in Cancer research (Chicago, Ill.) (15.04.2007)
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Absence of AKT1 mutations in glioblastoma
Bleeker, Fonnet E, Lamba, Simona, Zanon, Carlo, van Tilborg, Angela A, Leenstra, Sieger, Troost, Dirk, Hulsebos, Theo, Vandertop, W Peter, Bardelli, Alberto
Published in PloS one (20.05.2009)
Published in PloS one (20.05.2009)
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IDH1/2 Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors
Molenaar, Remco J, Radivoyevitch, Tomas, Nagata, Yasunobu, Khurshed, Mohammed, Przychodzen, Bartolomiej, Makishima, Hideki, Xu, Mingjiang, Bleeker, Fonnet E, Wilmink, Johanna W, Carraway, Hetty E, Mukherjee, Sudipto, Sekeres, Mikkael A, van Noorden, Cornelis J F, Maciejewski, Jaroslaw P
Published in Clinical cancer research (01.04.2018)
Published in Clinical cancer research (01.04.2018)
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IDH1 mutations at residue p.R132 (IDH1R¹³²) occur frequently in high-grade gliomas but not in other solid tumors
Bleeker, Fonnet E, Lamba, Simona, Leenstra, Sieger, Troost, Dirk, Hulsebos, Theo, Vandertop, W. Peter, Frattini, Milo, Molinari, Francesca, Knowles, Margaret, Cerrato, Aniello, Rodolfo, Monica, Scarpa, Aldo, Felicioni, Lara, Buttitta, Fiamma, Malatesta, Sara, Marchetti, Antonio, Bardelli, Alberto
Published in Human mutation (2009)
Published in Human mutation (2009)
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The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
Bleeker, Fonnet E, Atai, Nadia A, Lamba, Simona, Jonker, Ard, Rijkeboer, Denise, Bosch, Klazien S, Tigchelaar, Wikky, Troost, Dirk, Vandertop, W Peter, Bardelli, Alberto, Van Noorden, Cornelis J F
Published in Acta neuropathologica (01.04.2010)
Published in Acta neuropathologica (01.04.2010)
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Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
GRAVENDEEL, Lonneke A. M, KOUWENHOVEN, Mathilde C. M, DE MOOR, Bart, EILERS, Paul H. C, VAN DER SPEK, Peter J, KROS, Johan M, SILLEVIS SMITT, Peter A. E, VAN DEN BENT, Martin J, FRENCH, Pim J, GEVAERT, Olivier, DE ROOI, Johan J, STUBBS, Andrew P, ELZA DUIJM, J, DAEMEN, Anneleen, BLEEKER, Fonnet E, BRALTEN, Linda B. C, KLOOSTERHOF, Nanne K
Published in Cancer research (Chicago, Ill.) (01.12.2009)
Published in Cancer research (Chicago, Ill.) (01.12.2009)
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Large‐ and medium‐sized arterial aneurysms in two patients with SMAD4‐related juvenile polyposis syndrome
Weelden, Wenneke, Bleeker, Fonnet E., Stijn, Diana, Micha, Dimitra, Maugeri, Alessandra, Kuijpers, Taco W., Koch, Arjun D., Aalfs, Cora M., Wagner, Anja, Groenink, Maarten, Oldenrijk, Jakob, Baars, Marieke J., Duijkers, Floor A. M.
Published in American journal of medical genetics. Part A (01.10.2024)
Published in American journal of medical genetics. Part A (01.10.2024)
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Mutational profile of GNAQQ209 in human tumors
Lamba, Simona, Felicioni, Lara, Buttitta, Fiamma, Bleeker, Fonnet E, Malatesta, Sara, Corbo, Vincenzo, Scarpa, Aldo, Rodolfo, Monica, Knowles, Margaret, Frattini, Milo, Marchetti, Antonio, Bardelli, Alberto
Published in PloS one (31.08.2009)
Published in PloS one (31.08.2009)
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Discordant Staining Patterns and Microsatellite Results in Tumors of MSH6 Pathogenic Variant Carriers
van der Werf-’t Lam, Anne-Sophie, Terlouw, Diantha, Tops, Carli M., van Kan, Merel S., van Hest, Liselotte P., Gille, Hans J.P., Duijkers, Floor A.M., Wagner, Anja, Eikenboom, Ellis L., Letteboer, Tom G.W., de Jong, Mirjam M., Bajwa-ten Broeke, Sanne W., Bleeker, Fonnet E., Gomez Garcia, Encarna B., de Wind, Niels, van Wezel, J. Tom, Morreau, Hans, Suerink, Manon, Nielsen, Maartje
Published in Modern pathology (01.09.2023)
Published in Modern pathology (01.09.2023)
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Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution
Boots-Sprenger, Sandra H E, Sijben, Angelique, Rijntjes, Jos, Tops, Bastiaan B J, Idema, Albert J, Rivera, Andreana L, Bleeker, Fonnet E, Gijtenbeek, Anja M, Diefes, Kristin, Heathcock, Lindsey, Aldape, Kenneth D, Jeuken, Judith W M, Wesseling, Pieter
Published in Modern pathology (01.07.2013)
Published in Modern pathology (01.07.2013)
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Identifying the BRCA1 c.-107A > T variant in Dutch patients with a tumor BRCA1 promoter hypermethylation
de Jong, Vincent M. T., Pruntel, Roelof, Steenbruggen, Tessa G., Bleeker, Fonnet E., Nederlof, Petra, Hogervorst, Frans B. L., linn, Sabine C.
Published in Familial cancer (01.04.2023)
Published in Familial cancer (01.04.2023)
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Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines
Chau, Cindy, van Doorn, Remco, van Poppelen, Natasha M, van der Stoep, Nienke, Mensenkamp, Arjen R, Sijmons, Rolf H, van Paassen, Barbara W, van den Ouweland, Ans M W, Naus, Nicole C, van der Hout, Annemieke H, Potjer, Thomas P, Bleeker, Fonnet E, Wevers, Marijke R, van Hest, Liselotte P, Jongmans, Marjolijn C J, Marinkovic, Marina, Bleeker, Jaco C, Jager, Martine J, Luyten, Gregorius P M, Nielsen, Maartje
Published in Cancers (04.08.2019)
Published in Cancers (04.08.2019)
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Mutational profiling of kinases in glioblastoma
Bleeker, Fonnet E, Lamba, Simona, Zanon, Carlo, Molenaar, Remco J, Hulsebos, Theo J M, Troost, Dirk, van Tilborg, Angela A, Vandertop, W Peter, Leenstra, Sieger, van Noorden, Cornelis J F, Bardelli, Alberto
Published in BMC cancer (26.09.2014)
Published in BMC cancer (26.09.2014)
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Childhood tumours with a high probability of being part of a tumour predisposition syndrome; reason for referral for genetic consultation
Postema, Floor A.M, Hopman, Saskia M.J, Aalfs, Cora M, Berger, Lieke P.V, Bleeker, Fonnet E, Dommering, Charlotte J, Jongmans, Marjolijn C.J, Letteboer, Tom G.W, Olderode-Berends, Maran J.W, Wagner, Anja, Hennekam, Raoul C, Merks, Johannes H.M
Published in European journal of cancer (1990) (01.07.2017)
Published in European journal of cancer (1990) (01.07.2017)
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