Untargeted Metabolomic Analysis Combined With Multivariate Statistics Reveal Distinct Metabolic Changes in GPR40 Agonist-Treated Animals Related to Bile Acid Metabolism
Doerfler, Hannes, Botesteanu, Dana-Adriana, Blech, Stefan, Laux, Ralf
Published in Frontiers in molecular biosciences (15.01.2021)
Published in Frontiers in molecular biosciences (15.01.2021)
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Journal Article
Considerations for Human ADME Strategy and Design Paradigm Shift(s) – An Industry White Paper
Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Scarfe, Graeme, Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Groen, Bianca, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Bister, Bojan, Blech, Stefan, Lyer, Ramaswamy, Schulz, Simone I., Cuyckens, Filip, Moliner, Patricia
Published in Clinical pharmacology and therapeutics (01.04.2023)
Published in Clinical pharmacology and therapeutics (01.04.2023)
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Journal Article
Non‐Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece
Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Pedersen, Mette L., Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Blech, Stefan, Schulz, Simone I., Cuyckens, Filip, Nguyen, Mai Anh, Scarfe, Graeme
Published in Clinical pharmacology and therapeutics (01.05.2024)
Published in Clinical pharmacology and therapeutics (01.05.2024)
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Journal Article
Resolving the microcosmos of complex samples: UPLC/travelling wave ion mobility separation high resolution mass spectrometry for the analysis of in vivo drug metabolism studies
Blech, Stefan, Laux, Ralf
Published in International journal for ion mobility spectrometry (01.03.2013)
Published in International journal for ion mobility spectrometry (01.03.2013)
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Journal Article
Recommendations on the Use of Multiple Labels in Human Mass Balance Studies
Cuyckens, Filip, Hvenegaard, Mette G, Cassidy, Kenneth C, Spracklin, Douglas K, James, Alexander D, Pedersen, Mette L, Scarfe, Graeme, Wagner, David S, Georgi, Katrin, Schulz, Simone I, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A, Da Violante, Georges, Blech, Stefan, Moliner, Patricia, Young, Graeme C
Published in Drug metabolism and disposition (01.03.2024)
Published in Drug metabolism and disposition (01.03.2024)
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Journal Article
Best practices for metabolite quantification in drug development: updated recommendation from the European Bioanalysis Forum
Timmerman, Philip, Blech, Stefan, White, Stephen, Green, Martha, Delatour, Claude, McDougall, Stuart, Mannens, Geert, Smeraglia, John, Williams, Stephen, Young, Graeme
Published in Bioanalysis (01.06.2016)
Published in Bioanalysis (01.06.2016)
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Journal Article
LU92370I
SOLCA Flavio, JUNG Birgit, LANGKOPF Elke, BLECH Stefan, BAUM Anke, HIMMELSBACH Frank
Year of Publication 17.01.2019
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Year of Publication 17.01.2019
Patent
"derivado de quinazolina e seu uso, bem como composição farmacêutica"
Elke Baum, Frank Himmelsbach, Elke Langkopf, Flavio Solca, Stefan Blech, Birgit Jung
Year of Publication 27.07.2021
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Year of Publication 27.07.2021
Patent
4-Aminoquinazolines, method for producing thereof and pharmaceutical compositions containing them
BLECH STEFAN, HIMMELSBACH FRANK, LANGKOPF ELKE, SOLCA FLAVIO, JUNG BIRGIT
Year of Publication 04.08.2011
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Year of Publication 04.08.2011
Patent