Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing
Blandino-Rosano, Manuel, Barbaresso, Rebecca, Jimenez-Palomares, Margarita, Bozadjieva, Nadejda, Werneck-de-Castro, Joao Pedro, Hatanaka, Masayuki, Mirmira, Raghavendra G, Sonenberg, Nahum, Liu, Ming, Rüegg, Markus A, Hall, Michael N, Bernal-Mizrachi, Ernesto
Published in Nature communications (12.07.2017)
Published in Nature communications (12.07.2017)
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Journal Article
Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells
Xu, Weiwei, Qadir, M.M. Fahd, Nasteska, Daniela, Mota de Sa, Paula, Gorvin, Caroline M., Blandino-Rosano, Manuel, Evans, Charles R., Ho, Thuong, Potapenko, Evgeniy, Veluthakal, Rajakrishnan, Ashford, Fiona B., Bitsi, Stavroula, Fan, Jia, Bhondeley, Manika, Song, Kejing, Sure, Venkata N., Sakamuri, Siva S.V.P., Schiffer, Lina, Beatty, Wandy, Wyatt, Rachael, Frigo, Daniel E., Liu, Xiaowen, Katakam, Prasad V., Arlt, Wiebke, Buck, Jochen, Levin, Lonny R., Hu, Tony, Kolls, Jay, Burant, Charles F., Tomas, Alejandra, Merrins, Matthew J., Thurmond, Debbie C., Bernal-Mizrachi, Ernesto, Hodson, David J., Mauvais-Jarvis, Franck
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
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Journal Article
Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice
Blandino-Rosano, Manuel, Louzada, Ruy Andrade, Werneck-De-Castro, Joao Pedro, Lubaczeuski, Camila, Almaça, Joana, Rüegg, Markus A., Hall, Michael N., Leibowitz, Gil, Bernal-Mizrachi, Ernesto
Published in Molecular metabolism (Germany) (01.09.2023)
Published in Molecular metabolism (Germany) (01.09.2023)
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Journal Article
mTORC1 signaling and regulation of pancreatic β-cell mass
Blandino-Rosano, Manuel, Chen, Angela Y., Scheys, Joshua O., Alejandro, Emilyn U., Gould, Aaron P., Taranukha, Tatyana, Elghazi, Lynda, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Published in Cell cycle (Georgetown, Tex.) (15.05.2012)
Published in Cell cycle (Georgetown, Tex.) (15.05.2012)
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Journal Article
Exposure of mouse embryonic pancreas to metformin enhances the number of pancreatic progenitors
Gregg, Brigid, Elghazi, Lynda, Alejandro, Emilyn U., Smith, Michelle R., Blandino-Rosano, Manuel, El-Gabri, Deena, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Published in Diabetologia (01.12.2014)
Published in Diabetologia (01.12.2014)
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Journal Article
Nitric Oxide Is a Mediator of Antiproliferative Effects Induced by Proinflammatory Cytokines on Pancreatic Beta Cells
Blandino-Rosano, Manuel, Quintana-Lopez, Laura, Perez-Arana, Gonzalo, Cebada-Aleu, Alberto, Lechuga-Sancho, Alfonso, Aguilar-Diosdado, Manuel, Segundo, Carmen
Published in Mediators of Inflammation (01.01.2013)
Published in Mediators of Inflammation (01.01.2013)
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Journal Article
197-OR: Dynorphin, a Novel Paracrine Factor That Regulates Insulin Secretion
BLANDINO-ROSANO, MANUEL, PANZER, JULIA, BERNAL-MIZRACHI, ERNESTO
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Journal Article
2124-P: Raptor Levels Are Critical in the Adaptation of Beta Cells to High-Fat Diet
BLANDINO-ROSANO, MANUEL, BERNAL-MIZRACHI, ERNESTO
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia
Bozadjieva Kramer, Nadejda, Lubaczeuski, Camila, Blandino-Rosano, Manuel, Barker, Grant, Gittes, George K, Caicedo, Alejandro, Bernal-Mizrachi, Ernesto
Published in Diabetes (New York, N.Y.) (01.02.2021)
Published in Diabetes (New York, N.Y.) (01.02.2021)
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Journal Article
GRHR agonist MR-409 protects β-cells from streptozotocin-induced diabetes
Louzada, Ruy A., Blandino-Rosano, Manuel, Flores, Sebastian, Lubaczeuski, Camila, Cui, Tengjiao, Sha, Wei, Cai, Renzhi, Schally, Andrew V., Bernal-Mizrachi, Ernesto
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2023)
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Journal Article
Overexpression of Kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not β-Cell Mass
Alejandro, Emilyn U, Bozadjieva, Nadejda, Blandino-Rosano, Manuel, Wasan, Michelle Ann, Elghazi, Lynda, Vadrevu, Suryakiran, Satin, Leslie, Bernal-Mizrachi, Ernesto
Published in Diabetes (New York, N.Y.) (01.08.2017)
Published in Diabetes (New York, N.Y.) (01.08.2017)
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Journal Article
Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy
Israeli, Tal, Riahi, Yael, Garzon, Perla, Louzada, Ruy Andrade, Werneck-de-Castro, Joao Pedro, Blandino-Rosano, Manuel, Yeroslaviz-Stolper, Roni, Kadosh, Liat, Tornovsky-Babeay, Sharona, Hacker, Gilad, Israeli, Nitzan, Agmon, Orly, Tirosh, Boaz, Cerasi, Erol, Bernal-Mizrachi, Ernesto, Leibowitz, Gil
Published in Diabetes (New York, N.Y.) (01.03.2022)
Published in Diabetes (New York, N.Y.) (01.03.2022)
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Journal Article