Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung
Genschmer, Kristopher R., Russell, Derek W., Lal, Charitharth, Szul, Tomasz, Bratcher, Preston E., Noerager, Brett D., Abdul Roda, Mojtaba, Xu, Xin, Rezonzew, Gabriel, Viera, Liliana, Dobosh, Brian S., Margaroli, Camilla, Abdalla, Tarek H., King, Robert W., McNicholas, Carmel M., Wells, J. Michael, Dransfield, Mark T., Tirouvanziam, Rabindra, Gaggar, Amit, Blalock, J. Edwin
Published in Cell (10.01.2019)
Published in Cell (10.01.2019)
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Innate Immune Cell–Produced IL-17 Sustains Inflammation in Bullous Pemphigoid
Le Jan, Sébastien, Plée, Julie, Vallerand, David, Dupont, Aurélie, Delanez, Elodie, Durlach, Anne, Jackson, Patricia L., Edwin Blalock, J., Bernard, Philippe, Antonicelli, Frank
Published in Journal of investigative dermatology (01.12.2014)
Published in Journal of investigative dermatology (01.12.2014)
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Effects of hyperoxia on alveolar and pulmonary vascular development in germ-free mice
Dolma, Kalsang, Freeman, Amelia E, Rezonzew, Gabriel, Payne, Gregory A, Xu, Xin, Jilling, Tamas, Blalock, J Edwin, Gaggar, Amit, Ambalavanan, Namasivayam, Lal, Charitharth Vivek
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2020)
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2020)
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Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia
Lin, Vivian Y, Fain, Matthew D, Jackson, Patricia L, Berryhill, Taylor F, Wilson, Landon S, Mazur, Marina, Barnes, Stephen J, Blalock, J Edwin, Raju, S Vamsee, Rowe, Steven M
Published in American journal of respiratory cell and molecular biology (01.08.2019)
Published in American journal of respiratory cell and molecular biology (01.08.2019)
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A lactobacilli-based inhaled live biotherapeutic product attenuates pulmonary neutrophilic inflammation
Nicola, Teodora, Wenger, Nancy, Xu, Xin, Evans, Michael, Qiao, Luhua, Rezonzew, Gabriel, Yang, Youfeng, Jilling, Tamas, Margaroli, Camilla, Genschmer, Kristopher, Willis, Kent, Ambalavanan, Namasivayam, Blalock, J. Edwin, Gaggar, Amit, Lal, Charitharth Vivek
Published in Nature communications (19.08.2024)
Published in Nature communications (19.08.2024)
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A Critical Role for LTA₄H in Limiting Chronic Pulmonary Neutrophilic Inflammation
Snelgrove, Robert J., Jackson, Patricia L., Hardison, Matthew T., Noerager, Brett D., Kinloch, Andrew, Gaggar, Amit, Shastry, Suresh, Rowe, Steven M., Shim, Yun M., Hussell, Tracy, Blalock, J. Edwin
Published in Science (American Association for the Advancement of Science) (01.10.2010)
Published in Science (American Association for the Advancement of Science) (01.10.2010)
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Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease
Koelink, Pim J, Overbeek, Saskia A, Braber, Saskia, Morgan, Mary E, Henricks, Paul A J, Roda, Mojtaba Abdul, Verspaget, Hein W, Wolfkamp, Simone C, te Velde, Anje A, Jones, Caleb W, Jackson, Patricia L, Blalock, J Edwin, Sparidans, Rolf W, Kruijtzer, John A W, Garssen, Johan, Folkerts, Gert, Kraneveld, Aletta D
Published in Gut (01.04.2014)
Published in Gut (01.04.2014)
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A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation
Gaggar, Amit, Jackson, Patricia L, Noerager, Brett D, O'Reilly, Philip J, McQuaid, D. Brent, Rowe, Steven M, Clancy, J. P, Blalock, J. Edwin
Published in The Journal of immunology (1950) (15.04.2008)
Published in The Journal of immunology (1950) (15.04.2008)
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Doxycycline improves clinical outcomes during cystic fibrosis exacerbations
Xu, Xin, Abdalla, Tarek, Bratcher, Preston E, Jackson, Patricia L, Sabbatini, Gina, Wells, J Michael, Lou, Xiang-Yang, Quinn, Rebecca, Blalock, J Edwin, Clancy, J P, Gaggar, Amit
Published in The European respiratory journal (01.04.2017)
Published in The European respiratory journal (01.04.2017)
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Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-induced Emphysema
Roda, Mojtaba Abdul, Xu, Xin, Abdalla, Tarek H, Sadik, Mariam, Szul, Tomasz, Bratcher, Preston E, Viera, Liliana, Solomon, George M, Wells, J Michael, McNicholas, Carmel M, Redegeld, Frank A, Folkerts, Gert, Blalock, J Edwin, Gaggar, Amit
Published in American journal of respiratory cell and molecular biology (01.11.2019)
Published in American journal of respiratory cell and molecular biology (01.11.2019)
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Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection
Akthar, Samia, Patel, Dhiren F, Beale, Rebecca C, Peiró, Teresa, Xu, Xin, Gaggar, Amit, Jackson, Patricia L, Blalock, J Edwin, Lloyd, Clare M, Snelgrove, Robert J
Published in Nature communications (24.09.2015)
Published in Nature communications (24.09.2015)
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An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness
Patel, Dhiren F, Peiró, Teresa, Shoemark, Amelia, Akthar, Samia, Walker, Simone A, Grabiec, Aleksander M, Jackson, Patricia L, Hussell, Tracy, Gaggar, Amit, Xu, Xin, Trevor, Jennifer L, Li, Jindong, Steele, Chad, Tavernier, Gael, Blalock, J Edwin, Niven, Robert M, Gregory, Lisa G, Simpson, Angela, Lloyd, Clare M, Snelgrove, Robert J
Published in Science translational medicine (22.08.2018)
Published in Science translational medicine (22.08.2018)
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The development of novel LTA4H modulators to selectively target LTB4 generation
Low, Caroline M., Akthar, Samia, Patel, Dhiren F., Löser, Stephan, Wong, Chi-Tung, Jackson, Patricia L., Blalock, J. Edwin, Hare, Stephen A., Lloyd, Clare M., Snelgrove, Robert J.
Published in Scientific reports (17.03.2017)
Published in Scientific reports (17.03.2017)
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Matrix Metalloproteinase-8 Facilitates Neutrophil Migration through the Corneal Stromal Matrix by Collagen Degradation and Production of the Chemotactic Peptide Pro-Gly-Pro
Lin, Michelle, Jackson, Patricia, Tester, Angus M, Diaconu, Eugenia, Overall, Christopher M, Blalock, J. Edwin, Pearlman, Eric
Published in The American journal of pathology (01.07.2008)
Published in The American journal of pathology (01.07.2008)
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An in vivo model for extracellular vesicle-induced emphysema
Margaroli, Camilla, Madison, Matthew C, Viera, Liliana, Russell, Derek W, Gaggar, Amit, Genschmer, Kristopher R, Blalock, J Edwin
Published in JCI insight (22.02.2022)
Published in JCI insight (22.02.2022)
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N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD
O'Reilly, Philip, Jackson, Patricia L, Noerager, Brett, Parker, Suzanne, Dransfield, Mark, Gaggar, Amit, Blalock, J Edwin
Published in Respiratory research (18.05.2009)
Published in Respiratory research (18.05.2009)
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Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis
Turnbull, Andrew R., Pyle, Chloe J., Patel, Dhiren F., Jackson, Patricia L., Hilliard, Tom N., Regamey, Nicolas, Tan, Hui-Leng, Brown, Sarah, Thursfield, Rebecca, Short, Christopher, Mc Fie, Megan, Alton, Eric W.F.W., Gaggar, Amit, Blalock, J. Edwin, Lloyd, Clare M., Bush, Andrew, Davies, Jane C., Snelgrove, Robert J.
Published in Journal of cystic fibrosis (01.01.2020)
Published in Journal of cystic fibrosis (01.01.2020)
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Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?
Overbeek, Saskia A, Braber, Saskia, Koelink, Pim J, Henricks, Paul A J, Mortaz, Esmaeil, LoTam Loi, Adele T, Jackson, Patricia L, Garssen, Johan, Wagenaar, Gerry T M, Timens, Wim, Koenderman, Leo, Blalock, J Edwin, Kraneveld, Aletta D, Folkerts, Gert
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism
Zhao, Xue-Ke, Che, Pulin, Cheng, Ming-Liang, Zhang, Quan, Mu, Mao, Li, Hong, Luo, Yuan, Liang, Yue-Dong, Luo, Xin-Hua, Gao, Chang-Qing, Jackson, Patricia L, Wells, J Michael, Zhou, Yong, Hu, Meng, Cai, Guoqiang, Thannickal, Victor J, Steele, Chad, Blalock, J Edwin, Han, Xiaosi, Chen, Ching-Yi, Ding, Qiang
Published in PloS one (02.12.2016)
Published in PloS one (02.12.2016)
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The Matrikine Acetylated Proline-Glycine-Proline Couples Vascular Inflammation and Acute Cardiac Rejection
Payne, Gregory A, Li, Jindong, Xu, Xin, Jackson, Patricia, Qin, Hongwei, Pollock, David M, Wells, J Michael, Oparil, Suzanne, Leesar, Massoud, Patel, Rakesh P, Blalock, J Edwin, Gaggar, Amit
Published in Scientific reports (08.08.2017)
Published in Scientific reports (08.08.2017)
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