RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers
Nichols, Robert J., Haderk, Franziska, Stahlhut, Carlos, Schulze, Christopher J., Hemmati, Golzar, Wildes, David, Tzitzilonis, Christos, Mordec, Kasia, Marquez, Abby, Romero, Jason, Hsieh, Tientien, Zaman, Aubhishek, Olivas, Victor, McCoach, Caroline, Blakely, Collin M., Wang, Zhengping, Kiss, Gert, Koltun, Elena S., Gill, Adrian L., Singh, Mallika, Goldsmith, Mark A., Smith, Jacqueline A. M., Bivona, Trever G.
Published in Nature cell biology (01.09.2018)
Published in Nature cell biology (01.09.2018)
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Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
Shah, Khyati N., Bhatt, Roma, Rotow, Julia, Rohrberg, Julia, Olivas, Victor, Wang, Victoria E., Hemmati, Golzar, Martins, Maria M., Maynard, Ashley, Kuhn, Jonathan, Galeas, Jacqueline, Donnella, Hayley J., Kaushik, Swati, Ku, Angel, Dumont, Sophie, Krings, Gregor, Haringsma, Henry J., Robillard, Liliane, Simmons, Andrew D., Harding, Thomas C., McCormick, Frank, Goga, Andrei, Blakely, Collin M., Bivona, Trever G., Bandyopadhyay, Sourav
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Clinical Utility of Cell-Free DNA for the Detection of ALK Fusions and Genomic Mechanisms of ALK Inhibitor Resistance in Non-Small Cell Lung Cancer
McCoach, Caroline E, Blakely, Collin M, Banks, Kimberly C, Levy, Benjamin, Chue, Ben M, Raymond, Victoria M, Le, Anh T, Lee, Christine E, Diaz, Joseph, Waqar, Saiama N, Purcell, William T, Aisner, Dara L, Davies, Kurtis D, Lanman, Richard B, Shaw, Alice T, Doebele, Robert C
Published in Clinical cancer research (15.06.2018)
Published in Clinical cancer research (15.06.2018)
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Inactivation of Capicua drives cancer metastasis
Okimoto, Ross A, Breitenbuecher, Frank, Olivas, Victor R, Wu, Wei, Gini, Beatrice, Hofree, Matan, Asthana, Saurabh, Hrustanovic, Gorjan, Flanagan, Jennifer, Tulpule, Asmin, Blakely, Collin M, Haringsma, Henry J, Simmons, Andrew D, Gowen, Kyle, Suh, James, Miller, Vincent A, Ali, Siraj, Schuler, Martin, Bivona, Trever G
Published in Nature genetics (01.01.2017)
Published in Nature genetics (01.01.2017)
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NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer
Blakely, Collin M., Pazarentzos, Evangelos, Olivas, Victor, Asthana, Saurabh, Yan, Jenny Jiacheng, Tan, Irena, Hrustanovic, Gorjan, Chan, Elton, Lin, Luping, Neel, Dana S., Newton, William, Bobb, Kathryn L., Fouts, Timothy R., Meshulam, Jeffrey, Gubens, Matthew A., Jablons, David M., Johnson, Jeffrey R., Bandyopadhyay, Sourav, Krogan, Nevan J., Bivona, Trever G.
Published in Cell reports (Cambridge) (07.04.2015)
Published in Cell reports (Cambridge) (07.04.2015)
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Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins
Neel, Dana S, Allegakoen, David V, Olivas, Victor, Mayekar, Manasi K, Hemmati, Golzar, Chatterjee, Nilanjana, Blakely, Collin M, McCoach, Caroline E, Rotow, Julia K, Le, Anh, Karachaliou, Niki, Rosell, Rafael, Riess, Jonathan W, Nichols, Robert, Doebele, Robert C, Bivona, Trever G
Published in Cancer research (Chicago, Ill.) (01.02.2019)
Published in Cancer research (Chicago, Ill.) (01.02.2019)
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Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer
Nanjo, Shigeki, Wu, Wei, Karachaliou, Niki, Blakely, Collin M, Suzuki, Junji, Chou, Yu-Ting, Ali, Siraj M, Kerr, D Lucas, Olivas, Victor R, Shue, Jonathan, Rotow, Julia, Mayekar, Manasi K, Haderk, Franziska, Chatterjee, Nilanjana, Urisman, Anatoly, Yeo, Jia Chi, Skanderup, Anders J, Tan, Aaron C, Tam, Wai Leong, Arrieta, Oscar, Hosomichi, Kazuyoshi, Nishiyama, Akihiro, Yano, Seiji, Kirichok, Yuriy, Tan, Daniel Sw, Rosell, Rafael, Okimoto, Ross A, Bivona, Trever G
Published in The Journal of clinical investigation (01.07.2022)
Published in The Journal of clinical investigation (01.07.2022)
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Adjuvant chemotherapy guided by molecular profiling and improved outcomes in early stage, non-small cell lung cancer
Woodard, Gavitt A., MD, Wang, Sue X., BS, Kratz, Johannes R., MD, Zoon-Besselink, Clara T., BS, Chiang, Chun-Yuan, MBBS, Gubens, Matthew A., MD, MS, Jahan, Thierry M., MD, Blakely, Collin M., MD, PhD, Jones, Kirk D., MD, Mann, Michael J., MD, Jablons, David M., MD
Published in Clinical lung cancer (01.01.2018)
Published in Clinical lung cancer (01.01.2018)
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Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study
Ji, Jingran, Aredo, Jacqueline V., Piper-Vallillo, Andrew, Huppert, Laura, Rotow, Julia K., Husain, Hatim, Stewart, Susan, Cobb, Rosemary, Wakelee, Heather A., Blakely, Collin M., Wong, Melisa L., Gubens, Matthew A., Madani, Mohammad H., Digumarthy, Subba R., McCoach, Caroline, Piotrowska, Zofia, Neal, Joel W., Riess, Jonathan W.
Published in JTO clinical and research reports (01.03.2023)
Published in JTO clinical and research reports (01.03.2023)
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Phase 1 Study of Ceritinib Combined With Trametinib in Patients With Advanced ALK- or ROS1-Positive NSCLC
Lara, Matthew S., Gubens, Matthew A., Bacaltos, Bianca, Daran, Lea, Lim, Steffany L., Li, Tianhong, Gandara, David R., Bivona, Trever G., Riess, Jonathan W., Blakely, Collin M.
Published in JTO clinical and research reports (01.12.2022)
Published in JTO clinical and research reports (01.12.2022)
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Neoadjuvant oncogene-targeted therapy in early stage non-small cell lung cancer as a strategy to improve clinical outcome and identify early mechanisms of resistance
McCoach, Caroline E., MD PhD, Bivona, Trever G., MD PhD, Blakely, Collin M., MD PhD, Doebele, Robert C., MD PhD
Published in Clinical lung cancer (01.09.2016)
Published in Clinical lung cancer (01.09.2016)
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Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials
Doebele, Robert C, Drilon, Alexander, Paz-Ares, Luis, Siena, Salvatore, Shaw, Alice T, Farago, Anna F, Blakely, Collin M, Seto, Takashi, Cho, Byung Chul, Tosi, Diego, Besse, Benjamin, Chawla, Sant P, Bazhenova, Lyudmila, Krauss, John C, Chae, Young Kwang, Barve, Minal, Garrido-Laguna, Ignacio, Liu, Stephen V, Conkling, Paul, John, Thomas, Fakih, Marwan, Sigal, Darren, Loong, Herbert H, Buchschacher, Gary L, Garrido, Pilar, Nieva, Jorge, Steuer, Conor, Overbeck, Tobias R, Bowles, Daniel W, Fox, Elizabeth, Riehl, Todd, Chow-Maneval, Edna, Simmons, Brian, Cui, Na, Johnson, Ann, Eng, Susan, Wilson, Timothy R, Demetri, George D
Published in The lancet oncology (01.02.2020)
Published in The lancet oncology (01.02.2020)
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Efficacy and Safety of Rociletinib Versus Chemotherapy in Patients With EGFR-Mutated NSCLC: The Results of TIGER-3, a Phase 3 Randomized Study
Yang, James Chih-Hsin, Reckamp, Karen L., Kim, Young-Chul, Novello, Silvia, Smit, Egbert F., Lee, Jong-Seok, Su, Wu-Chou, Akerley, Wallace L., Blakely, Collin M., Groen, Harry J.M., Bazhenova, Lyudmila, Carcereny Costa, Enric, Chiari, Rita, Hsia, Te-Chun, Golsorkhi, Tony, Despain, Darrin, Shih, Danny, Popat, Sanjay, Wakelee, Heather
Published in JTO clinical and research reports (01.02.2021)
Published in JTO clinical and research reports (01.02.2021)
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Emerging Targeted Therapies for the Treatment of Non-small Cell Lung Cancer
Halliday, Patrick R., Blakely, Collin M., Bivona, Trever G.
Published in Current oncology reports (01.03.2019)
Published in Current oncology reports (01.03.2019)
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Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing
Maynard, Ashley, McCoach, Caroline E., Rotow, Julia K., Harris, Lincoln, Haderk, Franziska, Kerr, D. Lucas, Yu, Elizabeth A., Schenk, Erin L., Tan, Weilun, Zee, Alexander, Tan, Michelle, Gui, Philippe, Lea, Tasha, Wu, Wei, Urisman, Anatoly, Jones, Kirk, Sit, Rene, Kolli, Pallav K., Seeley, Eric, Gesthalter, Yaron, Le, Daniel D., Yamauchi, Kevin A., Naeger, David M., Bandyopadhyay, Sourav, Shah, Khyati, Cech, Lauren, Thomas, Nicholas J., Gupta, Anshal, Gonzalez, Mayra, Do, Hien, Tan, Lisa, Bacaltos, Bianca, Gomez-Sjoberg, Rafael, Gubens, Matthew, Jahan, Thierry, Kratz, Johannes R., Jablons, David, Neff, Norma, Doebele, Robert C., Weissman, Jonathan, Blakely, Collin M., Darmanis, Spyros, Bivona, Trever G.
Published in Cell (03.09.2020)
Published in Cell (03.09.2020)
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Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer
Gini, Beatrice, Thomas, Nicholas, Blakely, Collin M.
Published in Journal of thoracic disease (01.05.2020)
Published in Journal of thoracic disease (01.05.2020)
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Primary endpoints to assess the efficacy of novel therapeutic approaches in epidermal growth factor receptor-mutated, surgically resectable non-small cell lung cancer: A review
Blakely, Collin M., Weder, Walter, Bubendorf, Lukas, He, Jianxing, Majem, Margarita, Shyr, Yu, Chaft, Jamie E.
Published in Lung cancer (Amsterdam, Netherlands) (01.03.2023)
Published in Lung cancer (Amsterdam, Netherlands) (01.03.2023)
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