Old and New Approaches to Target the Hsp90 Chaperone
Sanchez, Jackee, Carter, Trever R, Cohen, Mark S, Blagg, Brian S J
Published in Current cancer drug targets (01.01.2020)
Published in Current cancer drug targets (01.01.2020)
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Novel HSP90 inhibitors effectively target functions of thyroid cancer stem cell preventing migration and invasion
White, Peter T., MD, Subramanian, Chitra, MBA, PhD, Zhu, Qing, MD, Zhang, Huaping, PhD, Zhao, Huiping, PhD, Gallagher, Robert, BS, Timmermann, Barbara N., PhD, Blagg, Brian S.J., PhD, Cohen, Mark S., MD, FACS
Published in Surgery (2016)
Published in Surgery (2016)
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c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells
Dunn, Diana M., Woodford, Mark R., Truman, Andrew W., Jensen, Sandra M., Schulman, Jacqualyn, Caza, Tiffany, Remillard, Taylor C., Loiselle, David, Wolfgeher, Donald, Blagg, Brian S.J., Franco, Lucas, Haystead, Timothy A., Daturpalli, Soumya, Mayer, Matthias P., Trepel, Jane B., Morgan, Rhodri M.L., Prodromou, Chrisostomos, Kron, Stephen J., Panaretou, Barry, Stetler-Stevenson, William G., Landas, Steve K., Neckers, Len, Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (11.08.2015)
Published in Cell reports (Cambridge) (11.08.2015)
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Gamendazole, an Orally Active Indazole Carboxylic Acid Male Contraceptive Agent, Targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and Stimulates Il1a Transcription in Rat Sertoli Cells
Tash, Joseph S, Chakrasali, Ramappa, Jakkaraj, Sudhakar R, Hughes, Jennifer, Smith, S. Kendall, Hornbaker, Kaori, Heckert, Leslie L, Ozturk, Sedide B, Hadden, M. Kyle, Kinzy, Terri Goss, Blagg, Brian S.J, Georg, Gunda I
Published in Biology of reproduction (01.06.2008)
Published in Biology of reproduction (01.06.2008)
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Natural products and other inhibitors of F1FO ATP synthase
Patel, Bhargav A., D’Amico, Terin L., Blagg, Brian S.J.
Published in European journal of medicinal chemistry (01.12.2020)
Published in European journal of medicinal chemistry (01.12.2020)
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Compound ranking based on a new mathematical measure of effectiveness using time course data from cell-based assays
Diaz, Francisco J, McDonald, Peter R, Roy, Anuradha, Taylor, Byron, Price, Ashleigh, Hall, Jessica, Blagg, Brian S J, Chaguturu, Rathnam
Published in Combinatorial chemistry & high throughput screening (01.03.2013)
Published in Combinatorial chemistry & high throughput screening (01.03.2013)
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Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C‐terminal Inhibitors
Garg, Gaurav, Forsberg, Leah K, Zhao, Huiping, Blagg, Brian S. J
Published in Chemistry : a European journal (21.11.2017)
Published in Chemistry : a European journal (21.11.2017)
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Journal Article
HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts
Pipalia, Nina H., Saad, Syed Z., Subramanian, Kanagaraj, Cross, Abigail, al-Motawa, Aisha, Garg, Kunal, Blagg, Brian S.J., Neckers, Len, Helquist, Paul, Wiest, Olaf, Ory, Daniel S., Maxfield, Frederick R.
Published in Journal of lipid research (01.01.2021)
Published in Journal of lipid research (01.01.2021)
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Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors
Byrd, Katherine M., Subramanian, Chitra, Sanchez, Jacqueline, Motiwala, Hashim F., Liu, Weiya, Cohen, Mark S., Holzbeierlein, Jeffrey, Blagg, Brian S. J.
Published in Chemistry : a European journal (10.05.2016)
Published in Chemistry : a European journal (10.05.2016)
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Pharmacologic dissection of the overlapping impact of heat shock protein family members on platelet function
Jackson, Joseph W., Rivera‐Marquez, Genesis M., Beebe, Kristin, Tran, Andy D., Trepel, Jane B., Gestwicki, Jason E., Blagg, Brian S. J., Ohkubo, Shuichi, Neckers, Leonard M.
Published in Journal of thrombosis and haemostasis (01.05.2020)
Published in Journal of thrombosis and haemostasis (01.05.2020)
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Journal Article
A systematic protocol for the characterization of Hsp90 modulators
Matts, Robert L., Brandt, Gary E.L., Lu, Yuanming, Dixit, Anshuman, Mollapour, Mehdi, Wang, Suiquan, Donnelly, Alison C., Neckers, Leonard, Verkhivker, Gennady, Blagg, Brian S.J.
Published in Bioorganic & medicinal chemistry (01.01.2011)
Published in Bioorganic & medicinal chemistry (01.01.2011)
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Identification and initial SAR of silybin: An Hsp90 inhibitor
Zhao, Huiping, Brandt, Gary E., Galam, Lakshmi, Matts, Robert L., Blagg, Brian S.J.
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
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Hsp90 Modulation for the Treatment of Alzheimer’s Disease
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