Antibody recognition of carbohydrate epitopes
Haji-Ghassemi, Omid, Blackler, Ryan J, Martin Young, N, Evans, Stephen V
Published in Glycobiology (Oxford) (01.09.2015)
Published in Glycobiology (Oxford) (01.09.2015)
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Journal Article
Antigen binding by conformational selection in near-germline antibodies
Blackler, Ryan J., Müller-Loennies, Sven, Pokorny-Lehrer, Barbara, Legg, Max S.G., Brade, Lore, Brade, Helmut, Kosma, Paul, Evans, Stephen V.
Published in The Journal of biological chemistry (01.05.2022)
Published in The Journal of biological chemistry (01.05.2022)
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Journal Article
Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei
Blackler, Ryan J., López-Guzmán, Arturo, Hager, Fiona F., Janesch, Bettina, Martinz, Gudrun, Gagnon, Susannah M. L., Haji-Ghassemi, Omid, Kosma, Paul, Messner, Paul, Schäffer, Christina, Evans, Stephen V.
Published in Nature communications (07.08.2018)
Published in Nature communications (07.08.2018)
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Journal Article
Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site
Blackler, Ryan J, Gagnon, Susannah M L, Polakowski, Robert, Rose, Natisha L, Zheng, Ruixiang B, Letts, James A, Johal, Asha R, Schuman, Brock, Borisova, Svetlana N, Palcic, Monica M, Evans, Stephen V
Published in Glycobiology (Oxford) (01.04.2017)
Published in Glycobiology (Oxford) (01.04.2017)
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Journal Article
Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner
Blackler, Ryan J, Evans, Dylan W, Smith, David F, Cummings, Richard D, Brooks, Cory L, Braulke, Thomas, Liu, Xinyu, Evans, Stephen V, Müller-Loennies, Sven
Published in Glycobiology (Oxford) (01.02.2016)
Published in Glycobiology (Oxford) (01.02.2016)
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Journal Article
1395 Targeting intracellular tumor antigens to Figureht cancer: discovery and development of functional and specific T-cell engagers against a MAGE-A4 pMHC
Tortora, Davide, Bergqvist, Peter, Jacobs, Tim, Farber, Patrick, Blackler, Ryan, Samiotakis, Antonios, Dhupar, Harveer, Robb, Craig, Goodman, Allison, Crichlow, Cindy-Lee, Cid, Melissa, Scortecci, Jessica Fernandes, Goya, Rodrigo, Chong, Lauren, Gibson, Kate, Salgado, Eduardo Solano, Xiang, Ping, Lee, Ahn, Yu, Irene, Conaghan, Gabrielle, Blamey, Nathalie, Li, Vivian, Puyraimond, Valentine de, Rowe, Patrick, Dalal, Kush, Masterman, Stephanie K, Fernandez, Tara, Tonikian, Raffi, Barnhart, Bryan C
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state
Johal, Asha R, Blackler, Ryan J, Alfaro, Javier A, Schuman, Brock, Borisova, Svetlana, Evans, Stephen V
Published in Glycobiology (Oxford) (01.03.2014)
Published in Glycobiology (Oxford) (01.03.2014)
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Journal Article
A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity
Blackler, Ryan J, Müller-Loennies, Sven, Brooks, Cory L, Evans, Dylan W, Brade, Lore, Kosma, Paul, Brade, Helmut, Evans, Stephen V
Published in Biochemistry (Easton) (26.04.2011)
Published in Biochemistry (Easton) (26.04.2011)
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Journal Article
Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments
Brooks, Cory L., Blackler, Ryan J., Gerstenbruch, Sandra, Kosma, Paul, Müller-Loennies, Sven, Brade, Helmut, Evans, Stephen V.
Published in Acta crystallographica. Section D, Biological crystallography. (01.12.2008)
Published in Acta crystallographica. Section D, Biological crystallography. (01.12.2008)
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Journal Article
role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen
Brooks, Cory L, Blackler, Ryan J, Sixta, Georg, Kosma, Paul, Müller-Loennies, Sven, Brade, Lore, Hirama, Tomoko, MacKenzie, C. Roger, Brade, Helmut, Evans, Stephen V
Published in Glycobiology (Oxford) (01.02.2010)
Published in Glycobiology (Oxford) (01.02.2010)
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Journal Article
Abstract 1788: Increasing the therapeutic index of IL12 by engineering for tumor specific protease activation
Bishop, Jennifer Leah, Blackler, Ryan, Volkers, Gesa, Poffenberger, Maya, Yu, Irene, Smith, Joel, Khodabandehloo, Akram, Arrafi, Sifa, Lau, Desmond, Stangle, Liz, Stenberg, Leisa, Zwierzchowski, Patricia, Dude, Iulia, Douda, David, Wickman, Grant, Proctor, Jeff, Rowse, Gerry, Madera, Laurence, Desjardins, Genevieve, Afacan, Nicole, Barnscher, Stuart, Mills, David, Spreter, Thomas, Dixit, Surjit
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
차폐된 IL12 융합 단백질 및 이의 사용 방법
BLACKLER RYAN, AFACAN NICOLE, SPRETER VON KREUDENSTEIN THOMAS, DESJARDINS GENEVIEVE, DOUDA DAVID, VOLKERS GESA
Year of Publication 20.02.2023
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Year of Publication 20.02.2023
Patent
Abstract 2373: Functional and specific T-cell engagers against a peptide-MHC tumor target
Tortora, Davide, Bergqvist, Peter, Goodman, Allison, Blackler, Ryan, Blamey, Nathalie, Carrara, Stefania, Chong, Lauren, Conaghan, Gabrielle, Crichlow, Cindy-Lee, de Puyraimond, Valentine, Dhupar, Harveer, Farber, Patrick, Scortecci, Jessica Fernandes, Gibson, Kate, Goya, Rodrigo, Lee, Ahn, Li, Franco, Pinsky, Tova, Robb, Craig, Rowe, Patrick, Samiotakis, Antonios, Salgado, Eduardo Solano, Xiang, Ping, Yu, Irene, Bullock, Kelly, Fernandez, Tara, Masterman, Stephanie K., Dalal, Kush, Jacobs, Tim, Barnhart, Bryan C.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 2935: ZW270, a conditionally masked IL-12 cytokine fusion protein displaying potent anti-tumor activity absent systemic toxicity
Poffenberger, Maya C., Bishop, Jennifer L., Blackler, Ryan J., Haworth, Kevin G., Booth, Steven, Hanson, Shalla, Proctor, Jeff R., Shao, I-Ting, Escalante, Nichole K., Siddappa, Dayananda, Smith, Joel, Anmole, Gursev, Konomura, Saki, Dawson, Nicholas A., Arrafi, Sifa, Lau, Desmond, Rowse, Gerry, Davies, Rupert H., von Kreudenstein, Thomas Spreter
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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