DNA topoisomerase-targeting chemotherapeutics: what’s new?
Cuya, Selma M., Bjornsti, Mary-Ann, van Waardenburg, Robert C.A.M.
Published in Cancer chemotherapy and pharmacology (01.07.2017)
Published in Cancer chemotherapy and pharmacology (01.07.2017)
Get full text
Journal Article
A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders
Ren, Guang, Kim, Teayoun, Kim, Hae-Suk, Young, Martin E, Muccio, Donald D, Atigadda, Venkatram R, Blum, Samuel I, Tse, Hubert M, Habegger, Kirk M, Bhatnagar, Sushant, Coric, Tatjana, Bjornsti, Mary-Ann, Shalev, Anath, Frank, Stuart J, Kim, Jeong-A
Published in Diabetes (New York, N.Y.) (01.09.2020)
Published in Diabetes (New York, N.Y.) (01.09.2020)
Get full text
Journal Article
4-Hydroxytamoxifen Induces Autophagic Death through K-Ras Degradation
KOHLI, Latika, KAZA, Niroop, CORIC, Tatjana, BYER, Stephanie J, BRASSIER, Nicole M, KLOCKE, Barbara J, BJORNSTI, Mary-Ann, CARROLL, Steven L, ROTH, Kevin A
Published in Cancer research (Chicago, Ill.) (15.07.2013)
Published in Cancer research (Chicago, Ill.) (15.07.2013)
Get full text
Journal Article
TOR Signaling Is a Determinant of Cell Survival in Response to DNA Damage
Shen, Changxian, Lancaster, Cynthia S., Shi, Bin, Guo, Hong, Thimmaiah, Padma, Bjornsti, Mary-Ann
Published in Molecular and Cellular Biology (01.10.2007)
Published in Molecular and Cellular Biology (01.10.2007)
Get full text
Journal Article
Development and histopathological characterization of tumorgraft models of pancreatic ductal adenocarcinoma
Garcia, Patrick L, Council, Leona N, Christein, John D, Arnoletti, J Pablo, Heslin, Marty J, Gamblin, Tracy L, Richardson, Joseph H, Bjornsti, Mary-Ann, Yoon, Karina J
Published in PloS one (23.10.2013)
Published in PloS one (23.10.2013)
Get full text
Journal Article
Cellular Strategies for Regulating DNA Supercoiling: A Single-Molecule Perspective
Koster, Daniel A., Crut, Aurélien, Shuman, Stewart, Bjornsti, Mary-Ann, Dekker, Nynke H.
Published in Cell (20.08.2010)
Published in Cell (20.08.2010)
Get full text
Journal Article
A Novel Active DNA Topoisomerase I in Leishmania donovani
Villa, Héctor, Otero Marcos, Ana R., Reguera, Rosa M., Balaña-Fouce, Rafael, Garcı́a-Estrada, Carlos, Pérez-Pertejo, Yolanda, Tekwani, Babu L., Myler, Peter J., Stuart, Kenneth D., Bjornsti, Mary-Ann, Ordóñez, David
Published in The Journal of biological chemistry (07.02.2003)
Published in The Journal of biological chemistry (07.02.2003)
Get full text
Journal Article
Defects in SUMO (Small Ubiquitin-related Modifier) Conjugation and Deconjugation Alter Cell Sensitivity to DNA Topoisomerase I-induced DNA Damage
Jacquiau, Hervé R., van Waardenburg, Robert C.A.M., Reid, Robert J.D., Woo, Michael H., Guo, Hong, Johnson, Erica S., Bjornsti, Mary-Ann
Published in The Journal of biological chemistry (24.06.2005)
Published in The Journal of biological chemistry (24.06.2005)
Get full text
Journal Article
Point mutations of the mTOR-RHEB pathway in renal cell carcinoma
Ghosh, Arindam P, Marshall, Christopher B, Coric, Tatjana, Shim, Eun-Hee, Kirkman, Richard, Ballestas, Mary E, Ikura, Mitsuhiko, Bjornsti, Mary-Ann, Sudarshan, Sunil
Published in Oncotarget (20.07.2015)
Published in Oncotarget (20.07.2015)
Get full text
Journal Article
Antitumour drugs impede DNA uncoiling by topoisomerase I
Bot, Elisa S. M, Koster, Daniel A, Dekker, Nynke H, Bjornsti, Mary-Ann, Palle, Komaraiah
Published in Nature (12.07.2007)
Published in Nature (12.07.2007)
Get full text
Journal Article
Locking the DNA Topoisomerase I Protein Clamp Inhibits DNA Rotation and Induces Cell Lethality
Woo, Michael H., Losasso, Carmen, Guo, Hong, Pattarello, Luca, Benedetti, Piero, Bjornsti, Mary-Ann
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
Get full text
Journal Article
Platinated DNA Adducts Enhance Poisoning of DNA Topoisomerase I by Camptothecin
van Waardenburg, Robert C.A.M., de Jong, Laurina A., van Eijndhoven, Maria A.J., Verseyden, Caroline, Pluim, Dick, Jansen, Lars E.T., Bjornsti, Mary-Ann, Schellens, Jan H.M.
Published in The Journal of biological chemistry (24.12.2004)
Published in The Journal of biological chemistry (24.12.2004)
Get full text
Journal Article
UBC9 Mutant Reveals the Impact of Protein Dynamics on Substrate Selectivity and SUMO Chain Linkages
Wright, Christine M, Whitaker, Robert H, Onuiri, Joshua E, Blackburn, Tessa, McGarity, Sierra, Bjornsti, Mary-Ann, Placzek, William J
Published in Biochemistry (Easton) (12.02.2019)
Published in Biochemistry (Easton) (12.02.2019)
Get full text
Journal Article
Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes
D'Alfonso, Anna, Di Felice, Francesca, Carlini, Valentina, Wright, Christine M, Hertz, Marla I, Bjornsti, Mary-Ann, Camilloni, Giorgio
Published in Journal of molecular biology (04.12.2016)
Published in Journal of molecular biology (04.12.2016)
Get full text
Journal Article
Substitution of Conserved Residues within the Active Site Alters the Cleavage Religation Equilibrium of DNA Topoisomerase I
Colley, William C., van der Merwe, Marie, Vance, John R., Burgin, Alex B., Bjornsti, Mary-Ann
Published in The Journal of biological chemistry (24.12.2004)
Published in The Journal of biological chemistry (24.12.2004)
Get full text
Journal Article