A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models
Stennicke, Henning R., Kjalke, Marianne, Karpf, Ditte M., Balling, Kristoffer W., Johansen, Peter B., Elm, Torben, Øvlisen, Kristine, Möller, Flemming, Holmberg, Heidi L., Gudme, Charlotte N., Persson, Egon, Hilden, Ida, Pelzer, Hermann, Rahbek-Nielsen, Henrik, Jespersgaard, Christina, Bogsnes, Are, Pedersen, Anette A., Kristensen, Anne K., Peschke, Bernd, Kappers, Wendy, Rode, Frederik, Thim, Lars, Tranholm, Mikael, Ezban, Mirella, Olsen, Eva H.N., Bjørn, Søren E.
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Published in Blood (14.03.2013)
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Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide
Østergaard, Henrik, Bjelke, Jais R., Hansen, Lene, Petersen, Lars Christian, Pedersen, Anette A., Elm, Torben, Møller, Flemming, Hermit, Mette B., Holm, Pernille K., Krogh, Thomas N., Petersen, Jørn M., Ezban, Mirella, Sørensen, Brit B., Andersen, Mette D., Agersø, Henrik, Ahmadian, Haleh, Balling, Kristoffer W., Christiansen, Marie Louise S., Knobe, Karin, Nichols, Timothy C., Bjørn, Søren E., Tranholm, Mikael
Published in Blood (25.08.2011)
Published in Blood (25.08.2011)
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A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders
Gandhi, Prafull S, Zivkovic, Minka, Østergaard, Henrik, Bonde, Amalie C, Elm, Torben, Løvgreen, Monika N, Schluckebier, Gerd, Johansson, Eva, Olsen, Ole H, Olsen, Eva H N, de Bus, Ian-Arris, Bloem, Karien, Alskär, Oskar, Rea, Catherine J, Bjørn, Søren E, Schutgens, Roger E, Sørensen, Benny, Urbanus, Rolf T, Faber, Johan H
Published in Nature cardiovascular research (01.02.2024)
Published in Nature cardiovascular research (01.02.2024)
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Generation and biochemical characterization of glycoPEGylated factor VIIa derivatives
Stennicke, Henning R, Ostergaard, Henrik, Bayer, Robert J, Kalo, Matt S, Kinealy, Kyle, Holm, Pernille K, Sørensen, Brit B, Zopf, David, Bjørn, Søren E
Published in Thrombosis and haemostasis (01.11.2008)
Published in Thrombosis and haemostasis (01.11.2008)
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High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)
Kirkeby, Agnete, Torup, Lars, Bochsen, Louise, Kjalke, Marianne, Abel, Kristin, Theilgaard-Monch, Kim, Johansson, Pär I, Bjørn, Søren E, Gerwien, Jens, Leist, Marcel
Published in Thrombosis and haemostasis (01.04.2008)
Published in Thrombosis and haemostasis (01.04.2008)
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Prolonged half-life of glycoPEGylated rFVIIa variants compared to native rFVIIa
Karpf, Ditte M, Sørensen, Brit B, Hermit, Mette B, Holmberg, Heidi L, Tranholm, Mikael, Bysted, Britta V, Groth, Andreas V, Bjørn, Søren E, Stennicke, Henning R
Published in Thrombosis research (01.08.2011)
Published in Thrombosis research (01.08.2011)
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Vatreptacog alfa from conception to clinical proof of concept
Persson, Egon, Olsen, Ole H, Bjørn, Søren E, Ezban, Mirella
Published in Seminars in thrombosis and hemostasis (01.04.2012)
Published in Seminars in thrombosis and hemostasis (01.04.2012)
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Prolonged effect of GlycoPEGylated rFVIIa (40k-PEG-rFVIIa) in rabbits correlates to activity in plasma
Johansen, Peter B, Bjørn, Søren E, Agersø, Henrik, Thorup, Inger, Hermit, Mette B, Sørensen, Brit, Stennicke, Henning R, Ezban, Mirella, Tranholm, Mikael
Published in Thrombosis and haemostasis (01.07.2010)
Published in Thrombosis and haemostasis (01.07.2010)
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Factor VIIa/tissue factor-dependent gene regulation and pro-coagulant activity: effect of factor VIIa concentration
Petersen, Lars C, Albrektsen, Tatjana, Hjortø, Gertrud M, Kjalke, Marianne, Bjørn, Søren E, Sørensen, Brit B
Published in Thrombosis and haemostasis (01.10.2007)
Published in Thrombosis and haemostasis (01.10.2007)
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Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human–murine species compatibility study
Petersen, Lars C., Nørby, Peder L., Branner, Sven, Sørensen, Brit B., Elm, Torben, Stennicke, Henning R., Persson, Egon, Bjørn, Søren E.
Published in Thrombosis research (2005)
Published in Thrombosis research (2005)
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Liquid pharmaceutical composition of factor VII polypeptide
HENRIKSEN ANETTE, ANDERSEN HENRIK SUNE, ROSSMEISL CHARLOTTE C, RASMUSSEN HANNE BENEDICTE, GANDHI PRAFULL S, BJORN SOREN E
Year of Publication 17.06.2015
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Year of Publication 17.06.2015
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Antifungal activity of chitin-binding PR-4 type proteins from barley grain and stressed leaf
Hejgaard, Jørn, Jacobsen, Susanne, Bjørn, Søren E., Kragh, Karsten M.
Published in FEBS letters (03.08.1992)
Published in FEBS letters (03.08.1992)
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