Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production
Clark, Michael P, Laughlin, Steven K, Laufersweiler, Matthew J, Bookland, Roger G, Brugel, Todd A, Golebiowski, Adam, Sabat, Mark P, Townes, Jennifer A, VanRens, John C, Djung, Jane F, Natchus, Michael G, De, Biswanath, Hsieh, Lily C, Xu, Susan C, Walter, Rick L, Mekel, Marlene J, Heitmeyer, Sandra A, Brown, Kimberly K, Juergens, Karen, Taiwo, Yetunde O, Janusz, Michael J
Published in Journal of medicinal chemistry (20.05.2004)
Published in Journal of medicinal chemistry (20.05.2004)
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The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production
Laughlin, Steven K., Clark, Michael P., Djung, Jane F., Golebiowski, Adam, Brugel, Todd A., Sabat, Mark, Bookland, Roger G., Laufersweiler, Matthew J., VanRens, John C., Townes, Jennifer A., De, Biswanath, Hsieh, Lily C., Xu, Susan C., Walter, Richard L., Mekel, Marlene J., Janusz, Michael J.
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
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Design and Synthesis of Piperazine-Based Matrix Metalloproteinase Inhibitors
Cheng, Menyan, De, Biswanath, Pikul, Stanislaw, Almstead, Neil G, Natchus, Michael G, Anastasio, Melanie V, McPhail, Sara J, Snider, Catherine E, Taiwo, Yetunde O, Chen, Longyin, Dunaway, C. Michelle, Gu, Fei, Dowty, Martin E, Mieling, Glen E, Janusz, Michael J, Wang-Weigand, Sherry
Published in Journal of medicinal chemistry (10.02.2000)
Published in Journal of medicinal chemistry (10.02.2000)
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Journal Article
Design, Synthesis, and Biological Evaluation of Potent Thiazine- and Thiazepine-Based Matrix Metalloproteinase Inhibitors
Almstead, Neil G, Bradley, Rimma S, Pikul, Stanislaw, De, Biswanath, Natchus, Michael G, Taiwo, Yetunde O, Gu, Fei, Williams, Lisa E, Hynd, Barbara A, Janusz, Michael J, Dunaway, C. Michelle, Mieling, Glen E
Published in Journal of medicinal chemistry (04.11.1999)
Published in Journal of medicinal chemistry (04.11.1999)
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Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines
Natchus, Michael G, Bookland, Roger G, Laufersweiler, Matthew J, Pikul, Staszek, Almstead, Neil G, De, Biswanath, Janusz, Michael J, Hsieh, Lily C, Gu, Fei, Pokross, Matthew E, Patel, Vikram S, Garver, Susan M, Peng, Sean X, Branch, Todd M, King, Selane L, Baker, Timothy R, Foltz, David J, Mieling, Glen E
Published in Journal of medicinal chemistry (29.03.2001)
Published in Journal of medicinal chemistry (29.03.2001)
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Design, Synthesis, and Biological Evaluation of Matrix Metalloproteinase Inhibitors Derived from a Modified Proline Scaffold
Cheng, Menyan, De, Biswanath, Almstead, Neil G, Pikul, Stanislaw, Dowty, Martin E, Dietsch, Charles R, Dunaway, C. Michelle, Gu, Fei, Hsieh, Lily C, Janusz, Michael J, Taiwo, Yetunde O, Natchus, Michael G, Hudlicky, Tomas, Mandel, Martin
Published in Journal of medicinal chemistry (30.12.1999)
Published in Journal of medicinal chemistry (30.12.1999)
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Journal Article
Anticancer Activity and Cellular Repression of c-MYC by the G-Quadruplex-Stabilizing 11-Piperazinylquindoline Is Not Dependent on Direct Targeting of the G-Quadruplex in the c-MYC Promoter
Boddupally, Peda V. L, Hahn, Seongmin, Beman, Cristina, De, Biswanath, Brooks, Tracy A, Gokhale, Vijay, Hurley, Laurence H
Published in Journal of medicinal chemistry (12.07.2012)
Published in Journal of medicinal chemistry (12.07.2012)
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The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold
Tullis, Joshua S., Laufersweiler, Matthew J., VanRens, John C., Natchus, Michael G., Bookland, Roger G., Almstead, Neil G., Pikul, Stanislaw, De, Biswanath, Hsieh, Lily C., Janusz, Michael J., Branch, Todd M., Peng, Sean X., Jin, Yingkun Y., Hudlicky, Tomas, Oppong, Kofi
Published in Bioorganic & medicinal chemistry letters (06.08.2001)
Published in Bioorganic & medicinal chemistry letters (06.08.2001)
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Journal Article
Correction: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex
Miranti, Cindy K., Moore, Sara, Kim, Yongeun, Chappeta, Venkateshwar Reddy, Wu, Kui, De, Biswanath, Gokhale, Vijay, Hurley, Laurence H., Reyes-Reyes, Elsa M.
Published in Oncotarget (30.06.2020)
Published in Oncotarget (30.06.2020)
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Journal Article
Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex
Miranti, Cindy K., Moore, Sara, Kim, Yongeun, Chappeta, Venkateshwar Reddy, Wu, Kui, De, Biswanath, Gokhale, Vijay, Hurley, Laurence H., Reyes-Reyes, Elsa M.
Published in Oncotarget (12.05.2020)
Published in Oncotarget (12.05.2020)
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Journal Article
Oxazolidinone to succinamide: a novel rearrangement reaction
Cheng, Menyan, De, Biswanath, Wahl, Christopher T., Almstead, Neil G., Natchus, Michael G., Pikul, Stanislaw
Published in Tetrahedron letters (13.08.1999)
Published in Tetrahedron letters (13.08.1999)
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Journal Article
Discovery of Potent, Achiral Matrix Metalloproteinase Inhibitors
Pikul, Stanislaw, McDow Dunham, Kelly L, Almstead, Neil G, De, Biswanath, Natchus, Michael G, Anastasio, Melanie V, McPhail, Sara J, Snider, Catherine E, Taiwo, Yetunde O, Rydel, Timothy, Dunaway, C. Michelle, Gu, Fei, Mieling, Glen E
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex
Miranti, Cindy K, Moore, Sara, Kim, Yongeun, Chappeta, Venkateshwar Reddy, Wu, Kui, De, Biswanath, Gokhale, Vijay, Hurley, Laurence H, Reyes-Reyes, Elsa M
Published in Oncotarget (30.06.2020)
Published in Oncotarget (30.06.2020)
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Journal Article
The anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinyl quindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter
Boddupally, Peda V. L., Hahn, Seongmin, Beman, Cristina, De, Biswanath, Brooks, Tracy A., Gokhale, Vijay, Hurley, Laurence H.
Published in Journal of medicinal chemistry (25.06.2012)
Published in Journal of medicinal chemistry (25.06.2012)
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Journal Article
The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)
Sabat, Mark, VanRens, John C., Laufersweiler, Matthew J., Brugel, Todd A., Maier, Jennifer, Golebiowski, Adam, De, Biswanath, Easwaran, Vijayasurian, Hsieh, Lily C., Walter, Richard L., Mekel, Marlene J., Evdokimov, Artem, Janusz, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.12.2006)
Published in Bioorganic & medicinal chemistry letters (01.12.2006)
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Journal Article
Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)
Clark, Michael P., George, Kelly M., Bookland, Roger G., Chen, Jack, Laughlin, Steven K., Thakur, Kumar D., Lee, Wenlin, Davis, Jan R., Cabrera, Ed J., Brugel, Todd A., VanRens, John C., Laufersweiler, Matthew J., Maier, Jennifer A., Sabat, Mark P., Golebiowski, Adam, Easwaran, Vijay, Webster, Mark E., De, Biswanath, Zhang, George
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
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Journal Article
The development of novel inhibitors of tumor necrosis factor-alpha production based on substituted [5,5]-bicyclic pyrozolones
Laufersweiler, Matthew, Brugel, Todd, Clark, Michael, Golebiowski, Adam, Bookland, Roger, Laughlin, Steven, Sabat, Mark, Townes, Jennifer, VanRens, John, De, Biswanath, Hsieh, Lily, Heitmeyer, Sandra, Juergens, Karen, Brown, Kimberly, Mekel, Marlene, Walter, Richard, Janusz, Michael
Published in Bioorganic & medicinal chemistry (16.11.2010)
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Published in Bioorganic & medicinal chemistry (16.11.2010)
Journal Article
Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3
Chen, Jack J., Thakur, Kumar D., Clark, Michael P., Laughlin, Steven K., George, Kelly M., Bookland, Roger G., Davis, Jan R., Cabrera, Edward J., Easwaran, Vijay, De, Biswanath, George Zhang, Y.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
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