Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS‐790052 in Humans: In Vitro and In Vivo Correlations
Fridell, Robert A., Wang, Chunfu, Sun, Jin‐Hua, O'Boyle, Donald R., Nower, Peter, Valera, Lourdes, Qiu, Dike, Roberts, Susan, Huang, Xin, Kienzle, Bernadette, Bifano, Marc, Nettles, Richard E., Gao, Min
Published in Hepatology (Baltimore, Md.) (01.12.2011)
Published in Hepatology (Baltimore, Md.) (01.12.2011)
Get full text
Journal Article
Calculation and Mitigation of Isotopic Interferences in Liquid Chromatography–Mass Spectrometry/Mass Spectrometry Assays and Its Application in Supporting Microdose Absolute Bioavailability Studies
Gu, Huidong, Wang, Jian, Aubry, Anne-Françoise, Jiang, Hao, Zeng, Jianing, Easter, John, Wang, Jun-sheng, Dockens, Randy, Bifano, Marc, Burrell, Richard, Arnold, Mark E
Published in Analytical chemistry (Washington) (05.06.2012)
Published in Analytical chemistry (Washington) (05.06.2012)
Get full text
Journal Article
Quantification of 4-Beta-Hydroxycholesterol in Human Plasma Using Automated Sample Preparation and LC-ESI-MS/MS Analysis
Goodenough, Angela K, Onorato, Joelle M, Ouyang, Zheng, Chang, Shu, Rodrigues, A. David, Kasichayanula, Sreeneeranj, Huang, Shu-Pang, Turley, Wesley, Burrell, Richard, Bifano, Marc, Jemal, Mohammed, LaCreta, Frank, Tymiak, Adrienne, Wang-Iverson, David
Published in Chemical research in toxicology (19.09.2011)
Published in Chemical research in toxicology (19.09.2011)
Get full text
Journal Article
Entecavir pharmacokinetics, safety, and tolerability after multiple ascending doses in healthy subjects
Yan, Jing-He, Bifano, Marc, Olsen, Steven, Smith, Robert A, Zhang, Duxi, Grasela, Dennis M, LaCreta, Frank
Published in Journal of clinical pharmacology (01.11.2006)
Published in Journal of clinical pharmacology (01.11.2006)
Get more information
Journal Article
Lack of an Effect of Human Immunodeficiency Virus Coinfection on the Pharmacokinetics of Entecavir in Hepatitis B Virus-Infected Patients
Zhu, Min, Bifano, Marc, Xu, Xu, Wang, Yonghua, LaCreta, Frank, Grasela, Dennis, Pfister, Marc
Published in Antimicrobial Agents and Chemotherapy (01.08.2008)
Published in Antimicrobial Agents and Chemotherapy (01.08.2008)
Get full text
Journal Article
Synthesis, Structure Proof, and Biological Activity of Epothilone Cyclopropanes
Johnson, James, Kim, Soong-Hoon, Bifano, Marc, DiMarco, John, Fairchild, Craig, Gougoutas, Jack, Lee, Francis, Long, Byron, Tokarski, John, Vite, Gregory
Published in Organic letters (01.06.2000)
Published in Organic letters (01.06.2000)
Get full text
Journal Article
Case report of successful peginterferon, ribavirin, and daclatasvir therapy for recurrent cholestatic hepatitis C after liver retransplantation
Fontana, Robert J., Hughes, Eric A., Appelman, Henry, Hindes, Robert, Dimitrova, Dessislava, Bifano, Marc
Published in Liver transplantation (01.09.2012)
Published in Liver transplantation (01.09.2012)
Get full text
Journal Article
Multiple ascending dose study of BMS‐790052, a nonstructural protein 5A replication complex inhibitor, in patients infected with hepatitis C virus genotype 1
Nettles, Richard E., Gao, Min, Bifano, Marc, Chung, Ellen, Persson, Anna, Marbury, Thomas C., Goldwater, Ronald, DeMicco, Michael P., Rodriguez‐Torres, Maribel, Vutikullird, Apinya, Fuentes, Ernesto, Lawitz, Eric, Lopez‐Talavera, Juan Carlos, Grasela, Dennis M.
Published in Hepatology (Baltimore, Md.) (01.12.2011)
Published in Hepatology (Baltimore, Md.) (01.12.2011)
Get full text
Journal Article
Assessment of pharmacokinetic interactions of the HCV NS5A replication complex inhibitor daclatasvir with antiretroviral agents: ritonavir-boosted atazanavir, efavirenz and tenofovir
BIFANO, Marc, HWANG, Carey, OOSTERHUIS, Berend, HARTSTRA, Jan, GRASELA, Dennis, TIESSEN, Renger, VELINOVA-DONGA, Maria, KANDOUSSI, Hamza, SEVINSKY, Heather, BERTZ, Richard
Published in Antiviral therapy (01.01.2013)
Published in Antiviral therapy (01.01.2013)
Get full text
Journal Article
Population Pharmacokinetic Analysis of Daclatasvir in Subjects with Chronic Hepatitis C Virus Infection
Chan, Phyllis, Li, Hanbin, Zhu, Li, Bifano, Marc, Eley, Timothy, Osawa, Mayu, Ueno, Takayo, Hughes, Eric, Bertz, Richard, Garimella, Tushar, AbuTarif, Malaz
Published in Clinical pharmacokinetics (01.10.2017)
Published in Clinical pharmacokinetics (01.10.2017)
Get full text
Journal Article
A Review of Daclatasvir Drug–Drug Interactions
Garimella, Tushar, You, Xiaoli, Wang, Reena, Huang, Shu-Pang, Kandoussi, Hamza, Bifano, Marc, Bertz, Richard, Eley, Timothy
Published in Advances in therapy (01.11.2016)
Published in Advances in therapy (01.11.2016)
Get full text
Journal Article
Single-dose pharmacokinetics and safety of daclatasvir in subjects with renal function impairment
Garimella, Tushar, Wang, Reena, Luo, Wen-Lin, Hwang, Carey, Sherman, Diane, Kandoussi, Hamza, Marbury, Thomas C, Alcorn, Harry, Bertz, Richard, Bifano, Marc
Published in Antiviral therapy (01.01.2015)
Published in Antiviral therapy (01.01.2015)
Get full text
Journal Article
An Open-Label Investigation into Drug–Drug Interactions Between Multiple Doses of Daclatasvir and Single-Dose Cyclosporine or Tacrolimus in Healthy Subjects
Bifano, Marc, Adamczyk, Robert, Hwang, Carey, Kandoussi, Hamza, Marion, Alan, Bertz, Richard J.
Published in Clinical drug investigation (01.05.2015)
Published in Clinical drug investigation (01.05.2015)
Get full text
Journal Article
Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection
Zeuzem, Stefan, Hézode, Christophe, Bronowicki, Jean-Pierre, Loustaud-Ratti, Veronique, Gea, Francisco, Buti, Maria, Olveira, Antonio, Banyai, Tivadar, Al-Assi, M. Tarek, Petersen, Joerg, Thabut, Dominique, Gadano, Adrian, Pruitt, Ronald, Makara, Mihály, Bourlière, Marc, Pol, Stanislas, Beumont-Mauviel, Maria, Ouwerkerk-Mahadevan, Sivi, Picchio, Gaston, Bifano, Marc, M Phee, Fiona, Boparai, Navdeep, Cheung, Kin, Hughes, Eric A, Noviello, Stephanie
Published in Journal of hepatology (01.02.2016)
Published in Journal of hepatology (01.02.2016)
Get full text
Journal Article
A sensitive and accurate liquid chromatography–tandem mass spectrometry method for quantitative determination of the novel hepatitis C NS5A inhibitor BMS-790052 (daclastasvir) in human plasma and urine
Jiang, Hao, Zeng, Jianing, Kandoussi, Hamza, Liu, Yifei, Wang, Xiaodong, Bifano, Marc, Cojocaru, Laura, Ryan, John, Arnold, Mark E.
Published in Journal of Chromatography A (06.07.2012)
Published in Journal of Chromatography A (06.07.2012)
Get full text
Journal Article
Using Population Pharmacokinetic and Pharmacodynamic Analyses of Entecavir in Pediatric Subjects to Simplify Dosing Recommendations
Chan, Phyllis, Mould, Diane R., Tarif, Malaz Abu, Reynolds, Laurie, LaCreta, Frank, Bertz, Richard, Bifano, Marc
Published in Clinical pharmacokinetics (01.12.2016)
Published in Clinical pharmacokinetics (01.12.2016)
Get full text
Journal Article
Effect of the coadministration of daclatasvir on the pharmacokinetics of a combined oral contraceptive containing ethinyl estradiol and norgestimate
Bifano, Marc, Sevinsky, Heather, Hwang, Carey, Kandoussi, Hamza, Jiang, Hao, Grasela, Dennis, Bertz, Richard
Published in Antiviral therapy (01.01.2014)
Published in Antiviral therapy (01.01.2014)
Get full text
Journal Article
Single- and multiple-ascending dose studies to evaluate the safety, tolerability, and pharmacokinetics of daclatasvir and asunaprevir in healthy male Japanese subjects
Shiozaki, Tomomi, Ueno, Takayo, Nagashima, Hirotaka, Yamahira, Naomi, Hiraoka, Masaki, Eley, Tim, Bifano, Marc, Bertz, Richard J
Published in International journal of clinical pharmacology and therapeutics (01.04.2015)
Published in International journal of clinical pharmacology and therapeutics (01.04.2015)
Get more information
Journal Article
Sequence-dependent Primer Synthesis by the Herpes Simplex Virus Helicase-Primase Complex
Tenney, D J, Sheaffer, A K, Hurlburt, W W, Bifano, M, Hamatake, R K
Published in The Journal of biological chemistry (21.04.1995)
Published in The Journal of biological chemistry (21.04.1995)
Get full text
Journal Article