Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1
KORTUM, Steven W, BENSON, Timothy E, BIENKOWSKI, Michael J, EMMONS, Thomas L, PRINCE, D. Bryan, PADDOCK, Donna J, TOMASSELLI, Alfredo G, MOON, Joseph B, LABORDE, Alice, TENBRINK, Ruth E
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
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Localization of the ROMK protein on apical membranes of rat kidney nephron segments
Xu, J Z, Hall, A E, Peterson, L N, Bienkowski, M J, Eessalu, T E, Hebert, S C
Published in American journal of physiology. Renal physiology (01.11.1997)
Published in American journal of physiology. Renal physiology (01.11.1997)
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Employing a superior BACE1 cleavage sequence to probe cellular APP processing
Tomasselli, Alfredo G., Qahwash, Isam, Emmons, Thomas L., Lu, Yifeng, Leone, Joseph W., Lull, June M., Fok, Kam F., Bannow, Carol A., Smith, Clark W., Bienkowski, Michael J., Heinrikson, Robert L., Yan, Riqiang
Published in Journal of neurochemistry (01.03.2003)
Published in Journal of neurochemistry (01.03.2003)
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Human β-Secretase (BACE) and BACE Inhibitors
John, Varghese, Beck, James P, Bienkowski, Michael J, Sinha, Sukanto, Heinrikson, Robert L
Published in Journal of medicinal chemistry (23.10.2003)
Published in Journal of medicinal chemistry (23.10.2003)
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BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: implications for Alzheimer's disease therapeutics
ROBERDS, Steven L, ANDERSON, John, JOHNSON-WOOD, Kelly, KAPPENMAN, Karl E, KAWABE, Thomas T, KOLA, Ismail, KUEHN, Ralf, LEE, Michael, LIU, Weiqun, MOTTER, Ruth, NICHOLS, Nanette F, POWER, Michael, BASI, Guriqbal, ROBERTSON, David W, SCHENK, Dale, SCHOOR, Michael, SHOPP, George M, SHUCK, Mary E, SINHA, Sukanto, SVENSSON, Kjell A, TATSUNO, Gwen, TINTRUP, Hartmut, WIJSMAN, John, BIENKOWSKI, Michael J, WRIGHT, Sarah, MCCONLOGUE, Lisa, BRANSTETTER, Daniel G, CHEN, Karen S, FREEDMAN, Stephen B, FRIGON, Normand L, GAMES, Dora, KANG HU
Published in Human molecular genetics (01.06.2001)
Published in Human molecular genetics (01.06.2001)
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The titerless infected-cells preservation and scale-up (TIPS) method for large-scale production of NO-sensitive human soluble guanylate cyclase (sGC) from insect cells infected with recombinant baculovirus
Wasilko, David J., Edward Lee, S., Stutzman-Engwall, Kim J., Reitz, Beverly A., Emmons, Thomas L., Mathis, Karl J., Bienkowski, Michael J., Tomasselli, Alfredo G., David Fischer, H.
Published in Protein expression and purification (01.06.2009)
Published in Protein expression and purification (01.06.2009)
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Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
Yan, Riqiang, Gurney, Mark E, Bienkowski, Michael J, Shuck, Mary E, Miao, Huiyi, Tory, Monica C, Pauley, Adele M, Brashler, John R, Stratman, Nancy C, Mathews, W. Rodney, Buhl, Allen E, Carter, Donald B, Tomasselli, Alfredo G, Parodi, Luis A, Heinrikson, Robert L
Published in Nature (London) (02.12.1999)
Published in Nature (London) (02.12.1999)
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Design of potent inhibitors of human β-secretase. Part 1
Freskos, John N., Fobian, Yvette M., Benson, Timothy E., Bienkowski, Michael J., Brown, David L., Emmons, Thomas L., Heintz, Robert, Laborde, Alice, McDonald, Joseph J., Mischke, Brent V., Molyneaux, John M., Moon, Joseph B., Mullins, Patrick B., Bryan Prince, D., Paddock, Donna J., Tomasselli, Alfredo G., Winterrowd, Gregory
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
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Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer
Fairbanks, Michael B., Mildner, Ana M., Leone, Joseph W., Cavey, Gregory S., Mathews, W. Rodney, Drong, Roger F., Slightom, Jerry L., Bienkowski, Michael J., Smith, Clark W., Bannow, Carol A., Heinrikson, Robert L.
Published in The Journal of biological chemistry (15.10.1999)
Published in The Journal of biological chemistry (15.10.1999)
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Design of potent inhibitors of human β-secretase. Part 2
Freskos, John N., Fobian, Yvette M., Benson, Timothy E., Moon, Joseph B., Bienkowski, Michael J., Brown, David L., Emmons, Thomas L., Heintz, Robert, Laborde, Alice, McDonald, Joseph J., Mischke, Brent V., Molyneaux, John M., Mullins, Patrick B., Bryan Prince, D., Paddock, Donna J., Tomasselli, Alfredo G., Winterrowd, Greg
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
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Purification and characterization of recombinant human soluble guanylate cyclase produced from baculovirus-infected insect cells
Emmons, Thomas L., Mathis, Karl J., Shuck, Mary E., Reitz, Beverly A., Curran, Daniel F., Walker, Mark C., Leone, Joseph W., Day, Jacqueline E., Bienkowski, Michael J., Fischer, H. David, Tomasselli, Alfredo G.
Published in Protein expression and purification (01.06.2009)
Published in Protein expression and purification (01.06.2009)
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Nucleotide sequence analysis of the human KCNJ1 potassium channel locus
Bock, Jeffrey H, Shuck, Mary E, Benjamin, Christopher W, Chee, Mea, Bienkowski, Michael J, Slightom, Jerry L
Published in Gene (25.03.1997)
Published in Gene (25.03.1997)
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BACE2 Functions as an Alternative α-Secretase in Cells
Yan, Riqiang, Munzner, Jennifer B., Shuck, Mary E., Bienkowski, Michael J.
Published in The Journal of biological chemistry (07.09.2001)
Published in The Journal of biological chemistry (07.09.2001)
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Journal Article
Potent and selective isophthalamide S 2 hydroxyethylamine inhibitors of BACE1
Kortum, Steven W., Benson, Timothy E., Bienkowski, Michael J., Emmons, Thomas L., Prince, D. Bryan, Paddock, Donna J., Tomasselli, Alfredo G., Moon, Joseph B., LaBorde, Alice, TenBrink, Ruth E.
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
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Activation of human eosinophils by platelet-derived growth factor
Bach, M K, Brashler, J R, Stout, B K, Johnson, H G, Sanders, M E, Lin, A H, Gorman, R R, Bienkowski, M J, Ishizaka, T
Published in International archives of allergy and immunology (01.01.1992)
Published in International archives of allergy and immunology (01.01.1992)
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ROMK inwardly rectifying ATP-sensitive K+ channel. II. Cloning and distribution of alternative forms
Boim, M A, Ho, K, Shuck, M E, Bienkowski, M J, Block, J H, Slightom, J L, Yang, Y, Brenner, B M, Hebert, S C
Published in The American journal of physiology (01.06.1995)
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Published in The American journal of physiology (01.06.1995)
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Potent and selective isophthalamide S sub(2) hydroxyethylamine inhibitors of BACE1
Kortum, Steven W, Benson, Timothy E, Bienkowski, Michael J, Emmons, Thomas L, Prince, DBryan, Paddock, Donna J, Tomasselli, Alfredo G, Moon, Joseph B, LaBorde, Alice, TenBrink, Ruth E
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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