Oral administration of the 5-HT2C receptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia
VICKERS, S. P, EASTON, N, WEBSTER, L. J, WYATT, A, BICKERDIKE, M. J, DOURISH, C. T, KENNETT, G. A
Published in Psychopharmacologia (01.05.2003)
Published in Psychopharmacologia (01.05.2003)
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Comparative effects of continuous infusion of mCPP, Ro 60‐0175 and d‐fenfluramine on food intake, water intake, body weight and locomotor activity in rats
Vickers, S P, Benwell, K R, Porter, R H, Bickerdike, M J, Kennett, G A, Dourish, C T
Published in British journal of pharmacology (01.07.2000)
Published in British journal of pharmacology (01.07.2000)
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Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists
RÖVER, S, ADAMS, D. R, HEBEISEN, P, KENNETT, G. A, KNIGHT, A. R, MALCOLM, C. S, MATTEI, P, MISRA, A, MIZRAHI, J, MULLER, M, PORTER, R. H. P, RICHTER, H, BENARDEAU, A, TAYLOR, S, VICKERS, S. P, BENTLEY, J. M, BICKERDIKE, M. J, BOURSON, A, CLIFFE, I. A, COASSOLO, P, DAVIDSON, J. E. P, DOURISH, C. T
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
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Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2 -a]pyrazines as potent and selective 5-HT2C receptor agonists
RICHTER, Hans G. F, ADAMS, D. R, KNIGHT, A. R, MALCOLM, C. S, MATTEI, P, MISRA, A, MIZRAHI, J, MONCK, N. J. T, PLANCHER, J.-M, ROEVER, S, ROFFEY, J. R. A, TAYLOR, S, BENARDEAU, A, VICKERS, S. P, BICKERDIKE, M. J, BENTLEY, J. M, BLENCH, T. J, CLIFFE, I. A, DOURISH, C, HEBEISEN, P, KENNETT, G. A
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Indoline derivatives as 5-HT2C receptor agonists
BENTLEY, J. M, ADAMS, D. R, GEORGE, A. R, GILES, P. R, HAMLYN, R. J, KENNETT, G. A, KNIGHT, A. R, MALCOLM, C. S, MANSELL, H. L, MISRA, A, MONCK, N. J. T, PRATT, R. M, BEBBINGTON, D, QUIRK, K, ROFFEY, J. R. A, VICKERS, S. P, CLIFFE, I. A, BENWELL, K. R, BICKERDIKE, M. J, DAVIDSON, J. E. P, DAWSON, C. E, DOURISH, C. T, DUNCTON, M. A. J, GAUR, S
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
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The Muscarinic Receptor Agonist Xanomeline Has an Antipsychotic-Like Profile in the Rat
Stanhope, K J, Mirza, N R, Bickerdike, M J, Bright, J L, Harrington, N R, Hesselink, M B, Kennett, G A, Lightowler, S, Sheardown, M J, Syed, R, Upton, R L, Wadsworth, G, Weiss, S M, Wyatt, A
Published in The Journal of pharmacology and experimental therapeutics (01.11.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.2001)
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5-HT2C receptor modulation and the treatment of obesity
Bickerdike, Mike J., Vickers, Steven P., Dourish, Colin T.
Published in Diabetes, obesity & metabolism (01.07.1999)
Published in Diabetes, obesity & metabolism (01.07.1999)
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Comparative effects of continuous infusion of m CPP, Ro 60‐0175 and d ‐fenfluramine on food intake, water intake, body weight and locomotor activity in rats
Vickers, S P, Benwell, K R, Porter, R H, Bickerdike, M J, Kennett, G A, Dourish, C T
Published in British journal of pharmacology (29.01.2009)
Published in British journal of pharmacology (29.01.2009)
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Toxicity of Alpidem, a Peripheral Benzodiazepine Receptor Ligand, but Not Zolpidem, in Rat Hepatocytes: Role of Mitochondrial Permeability Transition and Metabolic Activation
Berson, A, Descatoire, V, Sutton, A, Fau, D, Maulny, B, Vadrot, N, Feldmann, G, Berthon, B, Tordjmann, T, Pessayre, D
Published in The Journal of pharmacology and experimental therapeutics (01.11.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.2001)
Journal Article
Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia
Vickers, S P, Easton, N, Webster, L J, Wyatt, A, Bickerdike, M J, Dourish, C T, Kennett, G A
Published in Psychopharmacology (01.05.2003)
Get full text
Published in Psychopharmacology (01.05.2003)
Journal Article
Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists
Richter, Hans G F, Adams, D R, Benardeau, A, Bickerdike, M J, Bentley, J M, Blench, T J, Cliffe, I A, Dourish, C, Hebeisen, P, Kennett, G A, Knight, A R, Malcolm, C S, Mattei, P, Misra, A, Mizrahi, J, Monck, N J T, Plancher, J-M, Roever, S, Roffey, J R A, Taylor, S, Vickers, S P
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Indoline derivatives as 5-HT(2C) receptor agonists
Bentley, J M, Adams, D R, Bebbington, D, Benwell, K R, Bickerdike, M J, Davidson, J E P, Dawson, C E, Dourish, C T, Duncton, M A J, Gaur, S, George, A R, Giles, P R, Hamlyn, R J, Kennett, G A, Knight, A R, Malcolm, C S, Mansell, H L, Misra, A, Monck, N J T, Pratt, R M, Quirk, K, Roffey, J R A, Vickers, S P, Cliffe, I A
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
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Published in Bioorganic & medicinal chemistry letters (03.05.2004)
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Pyrrolo(iso)quinoline derivatives as 5-HT2C receptor agonists
ADAMS, David R, BENTLEY, Jonathan M, MALCOLM, Craig S, MANSELL, Howard L, MISRA, Anil, QUIRK, Kathleen, ROFFEY, Jonathan R. A, VICKERS, Steven P, BENWELL, Karen R, BICKERDIKE, Michael J, BODKIN, Corinna D, CLIFFE, Ian A, DOURISH, Colin T, GEORGE, Ashley R, KENNETT, Guy A, KNIGHT, Antony R
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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