Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens
Pfaller, M.A, Messer, S.A, Georgopapadakou, N, Martell, L.A, Besterman, J.M, Diekema, D.J
Published in Journal of Clinical Microbiology (01.12.2009)
Published in Journal of Clinical Microbiology (01.12.2009)
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A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly
Stewart, D. J., Donehower, R. C., Eisenhauer, E. A., Wainman, N., Shah, A. K., Bonfils, C., MacLeod, A. R., Besterman, J. M., Reid, G. K.
Published in Annals of oncology (01.05.2003)
Published in Annals of oncology (01.05.2003)
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Models of Human Metastatic Colon Cancer in Nude Mice Orthotopically Constructed by Using Histologically Intact Patient Specimens
Fu, Xinyu, Besterman, Jeffrey M., Monosov, Ann, Hoffman, Robert M.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.1991)
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Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors : demonstration of tumor-type specificity and implications for cancer chemotherapy
INTISAR HUSAIN, MOHLER, J. L, SEIGLER, H. F, BESTERMAN, J. M
Published in Cancer research (Chicago, Ill.) (15.01.1994)
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Published in Cancer research (Chicago, Ill.) (15.01.1994)
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Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination
Chen, Jingwen, Tomkinson, Alan E., Ramos, William, Mackey, Zachary B., Danehower, Sue, Walter, Christi A., Schultz, Roger A., Besterman, Jeffrey M., Husain, Intisar
Published in Molecular and Cellular Biology (01.10.1995)
Published in Molecular and Cellular Biology (01.10.1995)
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Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I
Luzzio, Michael J, Besterman, Jeffrey M, Emerson, David L, Evans, Michael G, Lackey, Karen, Leitner, Peter L, McIntyre, Gordon, Morton, Bradley, Myers, Peter L, Peel, Michael, Sisco, Jay M, Sternbach, Daniel D, Tong, Wei-Qin, Truesdale, Ann, Uehling, David E, Vuong, Alan, Yates, Julie
Published in Journal of medicinal chemistry (01.02.1995)
Published in Journal of medicinal chemistry (01.02.1995)
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Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange
J M Besterman, W S May, Jr, H LeVine, 3rd, E J Cragoe, Jr, P Cuatrecasas
Published in The Journal of biological chemistry (01.01.1985)
Published in The Journal of biological chemistry (01.01.1985)
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Collagen cross-link metabolites in urine as markers of bone metastases in prostatic carcinoma
Miyamoto, K K, McSherry, S A, Robins, S P, Besterman, J M, Mohler, J L
Published in The Journal of urology (01.04.1994)
Published in The Journal of urology (01.04.1994)
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Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation
Wang, Y.C., Burkhart, W.A., Mackey, Z.B., Moyer, M.B., Ramos, W, Husain, I, Chen, J, Besterman, J.M., Tomkinson, A.E.
Published in The Journal of biological chemistry (16.12.1994)
Published in The Journal of biological chemistry (16.12.1994)
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Diacylglycerol-Induced Translocation of Diacylglycerol Kinase: Use of Affinity-Purified Enzyme in a Reconstitution System
Besterman, Jeffrey M., Pollenz, Richard S., Booker, Elijah L., Cuatrecasas, Pedro
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1986)
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1986)
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Rigid Analogs of Camptothecin as DNA Topoisomerase I Inhibitors
Lackey, Karen, Besterman, Jeffrey M, Fletcher, Wade, Leitner, Peter, Morton, Bradley, Sternbach, Daniel D
Published in Journal of medicinal chemistry (01.03.1995)
Published in Journal of medicinal chemistry (01.03.1995)
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Journal Article
Water Soluble Inhibitors of Topoisomerase I: Quaternary Salt Derivatives of Camptothecin
Lackey, Karen, Sternbach, Daniel D, Croom, Dallas K, Emerson, David L, Evans, Michael G, Leitner, Peter L, Luzzio, Michael J, McIntyre, Gordon, Vuong, Alain, Yates, Julie, Besterman, Jeffrey M
Published in Journal of medicinal chemistry (02.02.1996)
Published in Journal of medicinal chemistry (02.02.1996)
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Journal Article
Amiloride intercalates into DNA and inhibits DNA topoisomerase II
Besterman, J M, Elwell, L P, Blanchard, S G, Cory, M
Published in The Journal of biological chemistry (25.09.1987)
Published in The Journal of biological chemistry (25.09.1987)
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Inhibition of Epidermal Growth Factor-Induced Mitogenesis by Amiloride and an Analog: Evidence against a Requirement for Na+/H+Exchange
Besterman, Jeffrey M., Tyrey, Scott J., Cragoe, Edward J., Cuatrecasas, Pedro
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1984)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1984)
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