Remote Effects in Macrolide Formation through Ring-Forming Olefin Metathesis: An Application to the Synthesis of Fully Active Epothilone Congeners
Meng, Dongfang, Su, Dai-Shi, Balog, Aaron, Bertinato, Peter, Sorensen, Erik J, Danishefsky, Samuel J, Zheng, Yu-Huang, Chou, Ting-Chao, He, Lifeng, Horwitz, Susan B
Published in Journal of the American Chemical Society (19.03.1997)
Published in Journal of the American Chemical Society (19.03.1997)
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Abstract 5703: Development of RVL-101, a CDK4/6-selective, small molecule inhibitor with superior CNS penetration and combinability potential for the effective treatment of primary and metastatic brain tumors
Campbell, John E., Pan, Bo-Sheng, Bower, Michael, Bertinato, Peter, Perez, Nisha, Andreu, Victoria Gras, Rana, Neha, Tabchouri, Sophia, Gupta, Ankit, Kallenbach, Jonah
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Total Syntheses of Epothilones A and B
Meng, Dongfang, Bertinato, Peter, Balog, Aaron, Su, Dai-Shi, Kamenecka, Ted, Sorensen, Erik J, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (22.10.1997)
Published in Journal of the American Chemical Society (22.10.1997)
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Discovery of microsomal triglyceride transfer protein (MTP) inhibitors with potential for decreased active metabolite load compared to dirlotapide
Robinson, Ralph P., Bartlett, Jeremy A., Bertinato, Peter, Bessire, Andrew J., Cosgrove, Judith, Foley, Patrick M., Manion, Tara B., Minich, Martha L., Ramos, Brenda, Reese, Matthew R., Schmahai, Theodore J., Swick, Andrew G., Tess, David A., Vaz, Alfin, Wolford, Angela
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS
BERGER GREGORY, BERTINATO PETER, ISHIZAKA SALLY, HANSEN HANS, SCHILLER SHAWN, YU ROBERT T, HAWKINS LYNN, BOIVIN ROCH, MACKEY MATTHEW, OGAWA CHIKAKO, NARAYAN SRIDHAR, ENDO ATSUSHI
Year of Publication 15.06.2016
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Year of Publication 15.06.2016
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In vitro and in vivo profile of 5-[(4' -trifluoromethyl -biphenyl -2-carbonyl ) -amino]-1H -indole -2 -carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity
JIN LI, BRONK, Brian S, HAVEN, Michelle L, KOLOSKO, Nicole L, BARRY, Chris J, MANION, Tara B, DIRLAM, John P, BLIZE, Alan E, BERTINATO, Peter, JAYNES, Burton H, HICKMAN, Anne, MISKELL, Christine, PILLAI, Usha A, TIBBITTS, Jay S
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
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COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
KALLENBACH, Jonah Milton, BERTINATO, Peter, RANA, Neha, CAMPBELL, John Emmerson, BOWER, Michael Jason
Year of Publication 15.08.2024
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Year of Publication 15.08.2024
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In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1 H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity
Li, Jin, Bronk, Brian S., Dirlam, John P., Blize, Alan E., Bertinato, Peter, Jaynes, Burton H., Hickman, Anne, Miskell, Christine, Pillai, Usha A., Tibbitts, Jay S., Haven, Michelle L., Kolosko, Nicole L., Barry, Chris J., Manion, Tara B.
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
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Discovery of potent and orally active MTP inhibitors as potential anti-obesity agents
Li, Jin, Bertinato, Peter, Cheng, Hengmiao, Cole, Bridget M., Bronk, Brian S., Jaynes, Burton H., Hickman, Anne, Haven, Michelle L., Kolosko, Nicole L., Barry, Chris J., Manion, Tara B.
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
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Total synthesis of (-)-epothilone A
Balog, A, Meng, DF, Kamenecka, T, Bertinato, P, Su, DS, Sorensen, EJ, Danishefsky, S
Published in Angewandte Chemie International Edition (01.12.1996)
Published in Angewandte Chemie International Edition (01.12.1996)
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Total synthesis of (-)-epothilone B: An extension of the Suzuki coupling method and insights into structure-activity relationships of the epothilones
Su, DS, Meng, DF, Bertinato, P, Balog, A, Sorensen, EJ, Danishefsky, SJ, Zheng, YH, Chou, TC, He, LF, Horwitz, SB
Published in Angewandte Chemie International Edition (18.04.1997)
Published in Angewandte Chemie International Edition (18.04.1997)
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SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS
BERTINATO, PETER, HAWKINS, LYNN, ISHIZAKA, SALLY, BOIVIN, ROCH, MACKEY, MATTHEW, HANSEN, HANS, SCHILLER, SHAWN, YU, ROBERT T, ENDO, ATSUSHI, OGAWA, CHIKAKO, NARAYAN, SRIDHAR, BERGER, GREGORY
Year of Publication 16.11.2021
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Year of Publication 16.11.2021
Patent
Structure-activity relationships of the epothilones and the first in vivo comparison with paclitaxel
Su, DS, Balog, A, Meng, DF, Bertinato, P, Danishefsky, SJ, Zheng, YH, Chou, TC, He, LF, Horwitz, SB
Published in Angewandte Chemie International Edition (17.10.1997)
Published in Angewandte Chemie International Edition (17.10.1997)
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Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone A series: Some surprising observations regarding their chemical and biological properties
Balog, Aaron, Bertinato, Peter, Su, Dai-Shi, Meng, Dongfang, Sorensen, Erik, Danishefsky, Samuel J., Zheng, Yu-Huang, Chou, Ting-Chao, He, Lifeng, Horwitz, Susan B.
Published in Tetrahedron letters (30.06.1997)
Published in Tetrahedron letters (30.06.1997)
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Azalide 3,6-Ketals: antibacterial activity and structure–Activity relationships of aryl and hetero aryl substituted analogues
Sakya, Subas M, Bertinato, Peter, Pratt, Bryan, Suarez-Contreras, Melani, Lundy, Kristin M, Minich, Martha L, Cheng, Hengmiao, Ziegler, Carl B, Kamicker, Barbara J, Hayashi, Shigeru F, Santoro, Sheryl L, George, David M, Bertsche, Camilla D
Published in Bioorganic & medicinal chemistry letters (07.04.2003)
Published in Bioorganic & medicinal chemistry letters (07.04.2003)
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AZALÍDEOS DE 13 MEMBROS, COMPOSIÇÕES FARMACÊUTICAS COMPREENDENDO OS MESMOS, MÉTODO PARA SUA PREPARAÇÃO BEM COMO SEUS USOS
JOHN PHILIP DIRLAM, COLMAN BRENDAN RAGAN, CARL BERNARD ZIEGLER, BARRY JAMES MORTON, PETER BERTINATO, ROBERT JOHN RAFKA, ALAN ELWOOD BLIZE
Year of Publication 16.11.2022
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Year of Publication 16.11.2022
Patent