Structural basis for CCR6 modulation by allosteric antagonists
Wasilko, David Jonathan, Gerstenberger, Brian S., Farley, Kathleen A., Li, Wei, Alley, Jennifer, Schnute, Mark E., Unwalla, Ray J., Victorino, Jorge, Crouse, Kimberly K., Ding, Ru, Sahasrabudhe, Parag V., Vincent, Fabien, Frisbie, Richard K., Dermenci, Alpay, Flick, Andrew, Choi, Chulho, Chinigo, Gary, Mousseau, James J., Trujillo, John I., Nuhant, Philippe, Mondal, Prolay, Lombardo, Vincent, Lamb, Daniel, Hogan, Barbara J., Minhas, Gurdeep Singh, Segala, Elena, Oswald, Christine, Windsor, Ian W., Han, Seungil, Rappas, Mathieu, Cooke, Robert M., Calabrese, Matthew F., Berstein, Gabriel, Thorarensen, Atli, Wu, Huixian
Published in Nature communications (31.08.2024)
Published in Nature communications (31.08.2024)
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Journal Article
Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator
BERSTEIN, G, BLANK, J. L, JHON, D.-Y, EXTON, J. H, RHEE, S. G, ROSS, E. M
Published in Cell (01.08.1992)
Published in Cell (01.08.1992)
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Journal Article
Ultra-Sensitive Measurement of IL-17A and IL-17F in Psoriasis Patient Serum and Skin
Soderstrom, Catherine, Berstein, Gabriel, Zhang, Weidong, Valdez, Hernan, Fitz, Lori, Kuhn, Max, Fraser, Stephanie
Published in The AAPS journal (01.07.2017)
Published in The AAPS journal (01.07.2017)
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Journal Article
RORγt inhibition ameliorates IL-23 driven experimental psoriatic arthritis by predominantly modulating γδ-T cells
Mortier, Céline, Gracey, Eric, Coudenys, Julie, Manuello, Teddy, Decruy, Tine, Maelegheer, Margaux, Stappers, Flore, Gilis, Elisabeth, Gaublomme, Djoere, Van Hoorebeke, Luc, Van Welden, Sophie, Ambler, Catherine, Hegen, Martin, Symanowicz, Peter, Steyn, Stefan, Berstein, Gabriel, Elewaut, Dirk, Venken, Koen
Published in Rheumatology (Oxford, England) (01.09.2023)
Published in Rheumatology (Oxford, England) (01.09.2023)
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Journal Article
The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis
Veale, Douglas J, McGonagle, Dennis, McInnes, Iain B, Krueger, James G, Ritchlin, Christopher T, Elewaut, Dirk, Kanik, Keith S, Hendrikx, Thijs, Berstein, Gabriel, Hodge, Jennifer, Telliez, Jean-Baptiste
Published in Rheumatology (Oxford, England) (01.02.2019)
Published in Rheumatology (Oxford, England) (01.02.2019)
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Journal Article
Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model
Bodenlenz, Manfred, Yeoh, Thean, Berstein, Gabriel, Mathew, Shibin, Shah, Jaymin, Banfield, Christopher, Hollingshead, Brett, Steyn, Stefanus J., Osgood, Sarah M., Beaumont, Kevin, Kainz, Sonja, Holeček, Christian, Trausinger, Gert, Raml, Reingard, Birngruber, Thomas
Published in Pharmaceutical research (01.02.2024)
Published in Pharmaceutical research (01.02.2024)
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Journal Article
Efficacy and safety of topical brepocitinib cream for mild-to-moderate chronic plaque psoriasis: a phase IIb randomized double-blind vehicle-controlled parallel-group study
Landis, Megan N, Smith, Stacy R, Berstein, Gabriel, Fetterly, Gerald, Ghosh, Pranab, Feng, Gang, Pradhan, Vivek, Aggarwal, Sudeepta, Banfield, Christopher, Peeva, Elena, Vincent, Michael S, Beebe, Jean S, Tarabar, Sanela
Published in British journal of dermatology (1951) (07.07.2023)
Published in British journal of dermatology (1951) (07.07.2023)
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Journal Article
Correction: Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model
Bodenlenz, Manfred, Yeoh, Thean, Berstein, Gabriel, Mathew, Shibin, Shah, Jaymin, Banfield, Christopher, Hollingshead, Brett, Steyn, Stefanus J., Osgood, Sarah M., Beaumont, Kevin, Kainz, Sonja, Holeček, Christian, Trausinger, Gert, Raml, Reingard, Birngruber, Thomas
Published in Pharmaceutical research (01.02.2024)
Published in Pharmaceutical research (01.02.2024)
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Journal Article
Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment
Kim, Jaehwan, Tomalin, Lewis, Lee, Julie, Fitz, Lori J., Berstein, Gabriel, Correa-da Rosa, Joel, Garcet, Sandra, Lowes, Michelle A., Valdez, Hernan, Wolk, Robert, Suarez-Farinas, Mayte, Krueger, James G.
Published in Journal of investigative dermatology (01.02.2018)
Published in Journal of investigative dermatology (01.02.2018)
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Journal Article
Early Quantification of Systemic Inflammatory Proteins Predicts Long-Term Treatment Response to Tofacitinib and Etanercept
Tomalin, Lewis E., Kim, Jaehwan, Correa da Rosa, Joel, Lee, Julie, Fitz, Lori J., Berstein, Gabriel, Valdez, Hernan, Wolk, Robert, Krueger, James G., Suárez-Fariñas, Mayte
Published in Journal of investigative dermatology (01.05.2020)
Published in Journal of investigative dermatology (01.05.2020)
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Journal Article
A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6 + T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation
Li, Wei, Crouse, Kimberly K, Alley, Jennifer, Frisbie, Richard K, Fish, Susan C, Andreyeva, Tatyana A, Reed, Lori A, Thorn, Mitchell, DiMaggio, Giovanni, Donovan, Carol B, Bennett, Donald, Garren, Jeonifer, Oziolor, Elias, Qian, Jesse, Newman, Leah, Vargas, Amanda P, Kumpf, Steven W, Steyn, Stefan J, Schnute, Mark E, Thorarensen, Atli, Hegen, Martin, Stevens, Erin, Collinge, Mark, Lanz, Thomas A, Vincent, Fabien, Vincent, Michael S, Berstein, Gabriel
Published in The Journal of pharmacology and experimental therapeutics (01.07.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2023)
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Journal Article
Discovery of 3-Cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yObenzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor Related Orphan Receptor C2 Inverse Agonist
Schnute, Mark E., Wennerstal, Mattias, Alley, Jennifer, Bengtsson, Martin, Blinn, James R., Bolten, Charles W., Braden, Timothy, Bonn, Tomas, Carlsson, Bo, Caspers, Nicole, Chen, Ming, Choi, Chulho, Collis, Leon P., Crouse, Kimberly, Farnegardh, Mathias, Fennell, Kimberly F., Fish, Susan, Flick, Andrew C., Goos-Nilsson, Annika, Gullberg, Hjalmar, Harris, Peter K., Heasley, Steven E., Hegen, Martin, Hromockyj, Alexander E., Hu, Xiao, Husman, Bolette, Janosik, Tomasz, Jones, Peter, Kaila, Neelu, Kallin, Elisabet, Kauppi, Bjorn, Kiefer, James R., Knafels, John, Koehler, Konrad, Kruger, Lars, Kurumbail, Ravi G., Kyne, Robert E., Li, Wei, Lofstedt, Joakim, Long, Scott A., Menard, Carol A., Mente, Scot, Messing, Dean, Meyers, Marvin J., Napierata, Lee, Noteberg, Daniel, Nuhant, Philippe, Pelc, Matthew J., Prinsen, Michael J., Rhonnstad, Patrik, Backstrom-Rydin, Eva, Sandberg, Johnny, Sandstrom, Maria, Shah, Falgun, Sjoberg, Maria, Sundell, Aron, Taylor, Alexandria P., Thorarensen, Atli, Trujillo, John I., Trzupek, John D., Unwalla, Ray, Vajdos, Felix F., Weinberg, Robin A., Wood, David C., Xing, Li, Zamaratski, Edouard, Zapf, Christoph W., Zhao, Yajuan, Wilhelmsson, Anna, Berstein, Gabriel
Published in Journal of medicinal chemistry (13.12.2018)
Published in Journal of medicinal chemistry (13.12.2018)
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Journal Article
Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonists
Schnute, Mark E., Trujillo, John I., Lee, Katherine L., Unwalla, Ray, Vajdos, Felix F., Kauppi, Björn, Nuhant, Philippe, Flick, Andrew C., Crouse, Kimberly K., Zhao, Yajuan, Samuel, Amanda, Lombardo, Vincent, Taylor, Alexandria P., Brault, Amy L., Knafels, John D., Vazquez, Michael L., Berstein, Gabriel
Published in ACS medicinal chemistry letters (09.02.2023)
Published in ACS medicinal chemistry letters (09.02.2023)
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Journal Article
Regulation of Phospholipase C-β1 by Gq and m1 Muscarinic Cholinergic Receptor
Biddlecome, Gloria H., Berstein, Gabriel, Ross, Elliott M.
Published in The Journal of biological chemistry (01.04.1996)
Published in The Journal of biological chemistry (01.04.1996)
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Journal Article
Identification of a new class of small molecule C5a receptor antagonists
Chen, Jack J., Cole, Derek C., Ciszewski, Greg, Crouse, Kimberly, Ellingboe, John W., Nowak, Pawel, Tawa, Gregory J., Berstein, Gabriel, Li, Wei
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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Journal Article
COMPARISON BETWEEN PURIFIED CEREBRAL AND ATRIAL MUSCARINIC ACETYLCHOLINE RECEPTORS: PIRENZEPINE BINDING AND THE EFFECT OF SULFHYDRYL REAGENTS
NISHIYAMA, TERUMASA, BERSTEIN, GABRIEL, IKEGAYA, TAKAYOSHI, HAGA, TATSUYA, ICHIYAMA, ARATA, KOBAYASHI, AKIRA, YAMAZAKI, NOBORU
Published in Biomedical Research (1989)
Published in Biomedical Research (1989)
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Journal Article
Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors
Waugh, M G, Challiss, R A, Berstein, G, Nahorski, S R, Tobin, A B
Published in Biochemical journal (15.02.1999)
Published in Biochemical journal (15.02.1999)
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