Epigenetic plasticity and the hallmarks of cancer
Flavahan, William A., Gaskell, Elizabeth, Bernstein, Bradley E.
Published in Science (American Association for the Advancement of Science) (21.07.2017)
Published in Science (American Association for the Advancement of Science) (21.07.2017)
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Journal Article
Epigenetic Reprogramming in Cancer
Suvà, Mario L., Riggi, Nicolo, Bernstein, Bradley E.
Published in Science (American Association for the Advancement of Science) (29.03.2013)
Published in Science (American Association for the Advancement of Science) (29.03.2013)
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Journal Article
Insulator dysfunction and oncogene activation in IDH mutant gliomas
Flavahan, William A., Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Venteicher, Andrew S., Stemmer-Rachamimov, Anat O., Suvà, Mario L., Bernstein, Bradley E.
Published in Nature (London) (07.01.2016)
Published in Nature (London) (07.01.2016)
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Journal Article
Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
Karaayvaz, Mihriban, Cristea, Simona, Gillespie, Shawn M., Patel, Anoop P., Mylvaganam, Ravindra, Luo, Christina C., Specht, Michelle C., Bernstein, Bradley E., Michor, Franziska, Ellisen, Leif W.
Published in Nature communications (04.09.2018)
Published in Nature communications (04.09.2018)
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Journal Article
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
Puram, Sidharth V., Tirosh, Itay, Parikh, Anuraag S., Patel, Anoop P., Yizhak, Keren, Gillespie, Shawn, Rodman, Christopher, Luo, Christina L., Mroz, Edmund A., Emerick, Kevin S., Deschler, Daniel G., Varvares, Mark A., Mylvaganam, Ravi, Rozenblatt-Rosen, Orit, Rocco, James W., Faquin, William C., Lin, Derrick T., Regev, Aviv, Bernstein, Bradley E.
Published in Cell (14.12.2017)
Published in Cell (14.12.2017)
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Journal Article
SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing
Isono, Kyoichi, Endo, Takaho A., Ku, Manching, Yamada, Daisuke, Suzuki, Rie, Sharif, Jafar, Ishikura, Tomoyuki, Toyoda, Tetsuro, Bernstein, Bradley E., Koseki, Haruhiko
Published in Developmental cell (30.09.2013)
Published in Developmental cell (30.09.2013)
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Journal Article
Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells
Ram, Oren, Goren, Alon, Amit, Ido, Shoresh, Noam, Yosef, Nir, Ernst, Jason, Kellis, Manolis, Gymrek, Melissa, Issner, Robbyn, Coyne, Michael, Durham, Timothy, Zhang, Xiaolan, Donaghey, Julie, Epstein, Charles B., Regev, Aviv, Bernstein, Bradley E.
Published in Cell (23.12.2011)
Published in Cell (23.12.2011)
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Journal Article
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
Ziller, Michael J, Müller, Fabian, Liao, Jing, Zhang, Yingying, Gu, Hongcang, Bock, Christoph, Boyle, Patrick, Epstein, Charles B, Bernstein, Bradley E, Lengauer, Thomas, Gnirke, Andreas, Meissner, Alexander
Published in PLoS genetics (01.12.2011)
Published in PLoS genetics (01.12.2011)
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Journal Article
Epigenome editing strategies for the functional annotation of CTCF insulators
Tarjan, Daniel R., Flavahan, William A., Bernstein, Bradley E.
Published in Nature communications (18.09.2019)
Published in Nature communications (18.09.2019)
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Journal Article
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
Finucane, Hilary K., Reshef, Yakir A., Anttila, Verneri, Slowikowski, Kamil, Gusev, Alexander, Byrnes, Andrea, Gazal, Steven, Loh, Po-Ru, Lareau, Caleb, Shoresh, Noam, Genovese, Giulio, Saunders, Arpiar, Macosko, Evan, Pollack, Samuela, Perry, John R. B., Buenrostro, Jason D., Bernstein, Bradley E., Raychaudhuri, Soumya, McCarroll, Steven, Neale, Benjamin M., Price, Alkes L.
Published in Nature genetics (01.04.2018)
Published in Nature genetics (01.04.2018)
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Journal Article
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Patel, Anoop P., Tirosh, Itay, Trombetta, John J., Shalek, Alex K., Gillespie, Shawn M., Wakimoto, Hiroaki, Cahill, Daniel P., Nahed, Brian V., Curry, William T., Martuza, Robert L., Louis, David N., Rozenblatt-Rosen, Orit, Suvà, Mario L., Regev, Aviv, Bernstein, Bradley E.
Published in Science (American Association for the Advancement of Science) (20.06.2014)
Published in Science (American Association for the Advancement of Science) (20.06.2014)
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Journal Article
Mapping and analysis of chromatin state dynamics in nine human cell types
Ernst, Jason, Kheradpour, Pouya, Mikkelsen, Tarjei S., Shoresh, Noam, Ward, Lucas D., Epstein, Charles B., Zhang, Xiaolan, Wang, Li, Issner, Robbyn, Coyne, Michael, Ku, Manching, Durham, Timothy, Kellis, Manolis, Bernstein, Bradley E.
Published in Nature (London) (05.05.2011)
Published in Nature (London) (05.05.2011)
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Journal Article
Charting a dynamic DNA methylation landscape of the human genome
Ziller, Michael J., Gu, Hongcang, Müller, Fabian, Donaghey, Julie, Tsai, Linus T.-Y., Kohlbacher, Oliver, De Jager, Philip L., Rosen, Evan D., Bennett, David A., Bernstein, Bradley E., Gnirke, Andreas, Meissner, Alexander
Published in Nature (London) (22.08.2013)
Published in Nature (London) (22.08.2013)
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Journal Article
ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression
Abdel-Wahab, Omar, Adli, Mazhar, LaFave, Lindsay M., Gao, Jie, Hricik, Todd, Shih, Alan H., Pandey, Suveg, Patel, Jay P., Chung, Young Rock, Koche, Richard, Perna, Fabiana, Zhao, Xinyang, Taylor, Jordan E., Park, Christopher Y., Carroll, Martin, Melnick, Ari, Nimer, Stephen D., Jaffe, Jacob D., Aifantis, Iannis, Bernstein, Bradley E., Levine, Ross L.
Published in Cancer cell (14.08.2012)
Published in Cancer cell (14.08.2012)
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Journal Article
Locus-specific editing of histone modifications at endogenous enhancers
Mendenhall, Eric M, Williamson, Kaylyn E, Reyon, Deepak, Zou, James Y, Ram, Oren, Joung, J Keith, Bernstein, Bradley E
Published in Nature biotechnology (01.12.2013)
Published in Nature biotechnology (01.12.2013)
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