Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Bernardim, Barbara, Cal, Pedro M.S.D., Matos, Maria J., Oliveira, Bruno L., Martínez-Sáez, Nuria, Albuquerque, Inês S., Perkins, Elizabeth, Corzana, Francisco, Burtoloso, Antonio C.B., Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L.
Published in Nature communications (26.10.2016)
Published in Nature communications (26.10.2016)
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Journal Article
Α,β-unsaturated diazoketones as versatile building blocks for the synthesis of hydroxylated piperidines, indolizidines and quinolizidines
Bernardim, Barbara, Lordello, Leonardo D, Burtoloso, Antonio C B
Published in Current topics in medicinal chemistry (01.09.2013)
Published in Current topics in medicinal chemistry (01.09.2013)
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Journal Article
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification
Lindstedt, Philip R, Aprile, Francesco A, Matos, Maria J, Perni, Michele, Bertoldo, Jean B, Bernardim, Barbara, Peter, Quentin, Jiménez-Osés, Gonzalo, Knowles, Tuomas P. J, Dobson, Christopher M, Corzana, Francisco, Vendruscolo, Michele, Bernardes, Gonçalo J. L
Published in ACS central science (28.08.2019)
Published in ACS central science (28.08.2019)
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Journal Article
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Bernardim, Barbara, Matos, Maria J., Ferhati, Xhenti, Compañón, Ismael, Guerreiro, Ana, Akkapeddi, Padma, Burtoloso, Antonio C. B., Jiménez-Osés, Gonzalo, Corzana, Francisco, Bernardes, Gonçalo J. L.
Published in Nature protocols (01.01.2019)
Published in Nature protocols (01.01.2019)
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Journal Article
Quaternization of Vinyl/Alkynyl Pyridine enables ultrafast cysteine‐selective protein modification and charge modulation
Matos, Maria J., Navo, Claudio D., Hakala, Tuuli, Ferhati, Xhenti, dos Santos Guerreiro, Ana Maria, Hartmann, David, Bernardim, Barbara, Saar, Kadi L., Compañón, Ismael, Corzana, Francisco, Knowles, Tuomas P. J., Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo
Published in Angewandte Chemie International Edition (13.05.2019)
Published in Angewandte Chemie International Edition (13.05.2019)
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Journal Article
Cathepsin B Processing Is Required for the In Vivo Efficacy of Albumin–Drug Conjugates
Bernardim, Barbara, Conde, João, Hakala, Tuuli, Becher, Julie B., Canzano, Mary, Vasco, Aldrin V., Knowles, Tuomas P. J., Cameron, Jason, Bernardes, Gonçalo J. L.
Published in Bioconjugate chemistry (21.02.2024)
Published in Bioconjugate chemistry (21.02.2024)
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Journal Article
α,β-Unsaturated Diazoketones as Useful Platforms in the Synthesis of Nitrogen Heterocycles
Burtoloso, Antonio C. B, Dias, Rafael M. P, Bernardim, Barbara
Published in Accounts of chemical research (21.04.2015)
Published in Accounts of chemical research (21.04.2015)
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Journal Article
Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable In Vitro and In-Cell Site-Specific Labeling
Bernardim, Barbara, Dunsmore, Lavinia, Li, He, Hocking, Brad, Nuñez-Franco, Reyes, Navo, Claudio D, Jiménez-Osés, Gonzalo, Burtoloso, Antonio C B, Bernardes, Gonçalo J L
Published in Bioconjugate chemistry (17.06.2020)
Published in Bioconjugate chemistry (17.06.2020)
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Journal Article
α,β-Unsaturated Diazoketones as Platforms in the Asymmetric Synthesis of Hydroxylated Alkaloids. Total Synthesis of 1‑Deoxy-8,8a-diepicastanospermine and 1,6-Dideoxyepicastanospermine and Formal Synthesis of Pumiliotoxin 251D
Bernardim, Barbara, Pinho, Vagner D, Burtoloso, Antonio C. B
Published in Journal of organic chemistry (02.11.2012)
Published in Journal of organic chemistry (02.11.2012)
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Journal Article
α,β-Unsaturated Diazoketones as Platforms in the Asymmetric Synthesis of Hydroxylated Alkaloids. Total Synthesis of 1-Deoxy-8,8a-diepicastanospermine and 1,6-Dideoxyepicastanospermine and Formal Synthesis of Pumiliotoxin 251 D
BERNARDIM, Barbara, PINHO, Vagner D, BURTOLOSO, Antonio C. B
Published in Journal of organic chemistry (2012)
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Published in Journal of organic chemistry (2012)
Journal Article
LED lighting as a simple, inexpensive, and sustainable alternative for Wolff rearrangementsElectronic supplementary information (ESI) available: NMR data and copy of spectra of all compounds. See DOI: 10.1039/c4ra15670f
Bernardim, Barbara, Hardman-Baldwin, Andrea M, Burtoloso, Antonio C. B
Year of Publication 27.01.2015
Year of Publication 27.01.2015
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Journal Article
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
Matos, Maria J., Navo, Claudio D., Hakala, Tuuli, Ferhati, Xhenti, Guerreiro, Ana, Hartmann, David, Bernardim, Barbara, Saar, Kadi L., Compañón, Ismael, Corzana, Francisco, Knowles, Tuomas P. J., Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Published in Angewandte Chemie (13.05.2019)
Published in Angewandte Chemie (13.05.2019)
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Journal Article