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Published in Antimicrobial Agents and Chemotherapy (01.05.2010)
Published in Antimicrobial Agents and Chemotherapy (01.05.2010)
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Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle
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Published in Antimicrobial agents and chemotherapy (01.10.2018)
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Virology analysis of chronic hepatitis B virus–infected patients treated for 28 days with JNJ‐56136379 monotherapy
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Published in Journal of viral hepatitis (01.11.2020)
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Antiviral Activity and Mode of Action of TMC647078, a Novel Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase
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Published in Antimicrobial Agents and Chemotherapy (01.08.2011)
Published in Antimicrobial Agents and Chemotherapy (01.08.2011)
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Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR
Lecoq, Lauriane, Brigandat, Louis, Huber, Rebecca, Fogeron, Marie-Laure, Wang, Shishan, Dujardin, Marie, Briday, Mathilde, Wiegand, Thomas, Callon, Morgane, Malär, Alexander, Durantel, David, Burdette, Dara, Berke, Jan Martin, Meier, Beat H., Nassal, Michael, Böckmann, Anja
Published in Nature communications (28.01.2023)
Published in Nature communications (28.01.2023)
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Structural Determinants for Membrane Association and Dynamic Organization of the Hepatitis C Virus NS3-4A Complex
Brass, Volker, Berke, Jan Martin, Montserret, Roland, Blum, Hubert E., Penin, François, Moradpour, Darius
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2008)
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Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation
Wang, Shishan, Fogeron, Marie-Laure, Schledorn, Maarten, Dujardin, Marie, Penzel, Susanne, Burdette, Dara, Berke, Jan Martin, Nassal, Michael, Lecoq, Lauriane, Meier, Beat H, Böckmann, Anja
Published in Frontiers in molecular biosciences (08.08.2019)
Published in Frontiers in molecular biosciences (08.08.2019)
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TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage
DEVOGELAERE, Benoit, BERKE, Jan Martin, LENZ, Oliver, CUMMINGS, Maxwell D, CLAYTON, Reginald F, VENDEVILLE, Sandrine, RABOISSON, Pierre, SIMMEN, Kenneth A, FANNING, Gregory C, LIN, Tse-I, VIJGEN, Leen, DEHERTOGH, Pascale, FRANSEN, Els, CLEIREN, Erna, VAN DER HELM, Liesbet, NYANGUILE, Origène, TAHRI, Abdellah, AMSSOMS, Katie
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
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Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055
Vendeville, Sandrine, Lin, Tse-I., Hu, Lili, Tahri, Abdellah, McGowan, David, Cummings, Maxwell D., Amssoms, Katie, Canard, Maxime, Last, Stefaan, Van den Steen, Iris, Devogelaere, Benoit, Rouan, Marie-Claude, Vijgen, Leen, Berke, Jan Martin, Dehertogh, Pascale, Fransen, Els, Cleiren, Erna, van der Helm, Liesbet, Fanning, Gregory, Van Emelen, Kristof, Nyanguile, Origène, Simmen, Kenny, Raboisson, Pierre
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Upregulation of Protein Phosphatase 2Ac by Hepatitis C Virus Modulates NS3 Helicase Activity through Inhibition of Protein Arginine Methyltransferase 1
Duong, Francois H T, Christen, Verena, Berke, Jan Martin, Penna, Sabina Hernandez, Moradpour, Darius, Heim, Markus H
Published in Journal of Virology (01.12.2005)
Published in Journal of Virology (01.12.2005)
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Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series
McGowan, David, Vendeville, Sandrine, Lin, Tse-I, Tahri, Abdellah, Hu, Lili, Cummings, Maxwell D., Amssoms, Katie, Berke, Jan Martin, Canard, Maxime, Cleiren, Erna, Dehertogh, Pascale, Last, Stefaan, Fransen, Els, Van Der Helm, Elisabeth, Van den Steen, Iris, Vijgen, Leen, Rouan, Marie-Claude, Fanning, Gregory, Nyanguile, Origène, Van Emelen, Kristof, Simmen, Kenneth, Raboisson, Pierre
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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MAPPIT as a high-throughput screening assay for modulators of protein-protein interactions in HIV and HCV
Van Schoubroeck, Bertrand, Van Acker, Koen, Dams, Géry, Jochmans, Dirk, Clayton, Reginald, Berke, Jan Martin, Lievens, Sam, Van der Heyden, José, Tavernier, Jan
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2012)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2012)
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WANG CHAO YUAN, BERKE JAN MARTIN, DERATT LINDSEY GRAHAM, KUDUK SCOTT D
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Year of Publication 03.02.2022
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Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus
Berke, Jan Martin, Dehertogh, Pascale, Vergauwen, Karen, Van Damme, Ellen, Mostmans, Wendy, Vandyck, Koen, Pauwels, Frederik
Published in Antimicrobial agents and chemotherapy (01.08.2017)
Published in Antimicrobial agents and chemotherapy (01.08.2017)
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Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379
Berke, Jan Martin, Dehertogh, Pascale, Vergauwen, Karen, Mostmans, Wendy, Vandyck, Koen, Raboisson, Pierre, Pauwels, Frederik
Published in Antimicrobial agents and chemotherapy (21.04.2020)
Published in Antimicrobial agents and chemotherapy (21.04.2020)
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BERKE JAN MARTIN, JACOBY EDGAR, GROSSE SANDRINE CELINE, COESEMANS ERWIN, LAST STEFAAN JULIEN, KESTELEYN BART RUDOLF ROMANIE, DOEBELIN CHRISTELLE CATHERINE CECILE, JONCKERS TIM HUGO MARIA, OBRINGER MICHEL, VERSCHUEREN WIM GASTON
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LAM MAN LU, BERKE JAN MARTIN, FLORES OSVALDO, HARTMAN GEORGE, KLUMPP KLAUS
Year of Publication 05.12.2018
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Year of Publication 05.12.2018
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DENG GANG, BERKE JAN MARTIN, JIANG YIMIN, GROSSE SANDRINE CELINE, PIETERS SERGE MARIA ALOYSIUS, KESTELEYN BART RUDOLF ROMANIE, RABOISSON PIERRE JEAN MARIE BERNARD, XU YANPING, JONCKERS TIM HUGO MARIA, CHENG ZHANLING, DERATT LINDSEY GRAHAM, VANDYCK KOEN, MARTINEZ LAMENCA CAROLINA, HU LILI, KUDUK SCOTT D, VERSCHUEREN WIM GASTON, LECOMTE MORGAN CHARLES R
Year of Publication 04.02.2022
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Year of Publication 04.02.2022
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