A Novel Inhibitor of Dengue Virus Replication That Targets the Capsid Protein
Byrd, Chelsea M, Dai, Dongcheng, Grosenbach, Douglas W, Berhanu, Aklile, Jones, Kevin F, Cardwell, Kara B, Schneider, Christine, Wineinger, Kristin A, Page, Jessica M, Harver, Chris, Stavale, Eric, Tyavanagimatt, Shanthakumar, Stone, Melialani A, Bartenschlager, Ralf, Scaturro, Pietro, Hruby, Dennis E, Jordan, Robert
Published in Antimicrobial Agents and Chemotherapy (01.01.2013)
Published in Antimicrobial Agents and Chemotherapy (01.01.2013)
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Novel Benzoxazole Inhibitor of Dengue Virus Replication That Targets the NS3 Helicase
BYRD, Chelsea M, GROSENBACH, Douglas W, WINEINGER, Kristin A, PAGE, Jessica, STAVALE, Eric, STONE, Melialani A, FULLER, Kathleen P, LOVEJOY, Candace, LEEDS, Janet M, HRUBY, Dennis E, JORDAN, Robert, BERHANU, Aklile, DONGCHENG DAI, JONES, Kevin F, CARDWELL, Kara B, SCHNEIDER, Christine, GUANG YANG, TYAVANAGIMATT, Shanthakumar, HARVER, Chris
Published in Antimicrobial Agents and Chemotherapy (01.04.2013)
Published in Antimicrobial Agents and Chemotherapy (01.04.2013)
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Journal Article
ST-246 Inhibits In Vivo Poxvirus Dissemination, Virus Shedding, and Systemic Disease Manifestation
BERHANU, Aklile, KING, David S, MOSIER, Stacie, JORDAN, Robert, JONES, Kevin F, HRUBY, Dennis E, GROSENBACH, Douglas W
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
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Journal Article
Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice
Grosenbach, Douglas W, Berhanu, Aklile, King, David S, Mosier, Stacie, Jones, Kevin F, Jordan, Robert A, Bolken, Tove' C, Hruby, Dennis E
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2010)
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Journal Article
Vaccination of BALB/c Mice with Escherichia coli-Expressed Vaccinia Virus Proteins A27L, B5R, and D8L Protects Mice from Lethal Vaccinia Virus Challenge
BERHANU, Aklile, WILSON, Rebecca L, HONEYCHURCH, Kady M, GROSENBACH, Douglas W, JONES, Kevin F, HRUBY, Dennis E, KIRKWOOD-WATTS, Dana L, KING, David S, WARREN, Travis K, LUND, Susan A, BROWN, Lindsay L, KRUPKIN, Alex K, VANDERMAY, Erin, WEIMERS, Will
Published in Journal of Virology (01.04.2008)
Published in Journal of Virology (01.04.2008)
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Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus challenge
Russo, Andrew T., Berhanu, Aklile, Bigger, Catherine B., Prigge, Jon, Silvera, Peter M., Grosenbach, Douglas W., Hruby, Dennis
Published in Vaccine (16.01.2020)
Published in Vaccine (16.01.2020)
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Journal Article
Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection
Berhanu, Aklile, Prigge, Jonathan T, Silvera, Peter M, Honeychurch, Kady M, Hruby, Dennis E, Grosenbach, Douglas W
Published in Antimicrobial agents and chemotherapy (01.07.2015)
Published in Antimicrobial agents and chemotherapy (01.07.2015)
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1305. Comparison of Pharmacokinetics of DSTA4637S, a novel THIOMABTM Antibody-Antibiotic Conjugate, in Patients with Staphylococcus aureus Bacteremia Receiving Standard-of-Care Antibiotics with Pharmacokinetics in Healthy Volunteers
Rymut, Sharon M, Deng, Rong, Owen, Ryan, Saad, Ola, Berhanu, Aklile, Lim, Jeremy, Carrasco-Triguero, Montserrat, Couch, Jessica A, Peck, Melicent C
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
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167. A Phase 1b, Randomized, Double-blind, Placebo-controlled, Multiple-ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Patients with staphylococcus Aureus Bacteremia Receiving Standard-of-care Antibiotics
Lim, Jeremy, Lewin-Koh, Nicholas, Chu, Tom, Rymut, Sharon M, Berhanu, Aklile, Carrasco-Triguero, Montserrat, Rosenberger, Carrie C, Hazenbos, Wouter L, Miller, Loren G, Fowler, Vance G, Miro, Jose M, Couch, Jessica A, Peck, Melicent C
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
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Journal Article
Sustained Circulating Bacterial Deoxyribonucleic Acid Is Associated With Complicated Staphylococcus aureus Bacteremia
Gutierrez, Johnny, Guimaraes, Alessander O, Lewin-Koh, Nicholas, Berhanu, Aklile, Xu, Min, Cao, Yi, Kim, Janice, Yan, Donghong, Chang, Joanna K, Dinoso, Jason B, Koss, Catherine A, Clemenzi-Allen, Angelo, Chambers, Henry F, Peck, Melicent C, Baruch, Amos, Rosenberger, Carrie M
Published in Open forum infectious diseases (01.04.2019)
Published in Open forum infectious diseases (01.04.2019)
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Journal Article
Impact of ST-246® on ACAM2000™ smallpox vaccine reactogenicity, immunogenicity, and protective efficacy in immunodeficient mice
Berhanu, Aklile, King, David S, Mosier, Stacie, Jordan, Robert, Jones, Kevin F, Hruby, Dennis E, Grosenbach, Douglas W
Published in Vaccine (16.12.2010)
Published in Vaccine (16.12.2010)
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Journal Article
Impact of ST-246 registered on ACAM2000[TM] smallpox vaccine reactogenicity, immunogenicity, and protective efficacy in immunodeficient mice
Berhanu, Aklile, King, David S, Mosier, Stacie, Jordan, Robert, Jones, Kevin F, Hruby, Dennis E, Grosenbach, Douglas W
Published in Vaccine (16.12.2010)
Published in Vaccine (16.12.2010)
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Journal Article
Small Molecule Inhibitors of Dengue Virus Replication are Active In Vivo
Byrd, Chelsea, Harver, Chris, Cardwell, Kara, Grosenbach, Doug, Berhanu, Aklile, Dai, Dongcheng, Hruby, Dennis, Jordan, Robert
Published in Antiviral research (01.04.2010)
Published in Antiviral research (01.04.2010)
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Journal Article
Combinational FLt3 ligand and granulocyte macrophage colony- stimulating factor treatment promotes enhanced tumor infiltration by dendritic cells and antitumor CD8+ T-cell cross-priming but is ineffective as a therapy
BERHANU, Aklile, JIAN HUANG, ALBER, Sean M, WATKINS, Simon C, STORKUS, Walter J
Published in Cancer research (Chicago, Ill.) (01.05.2006)
Published in Cancer research (Chicago, Ill.) (01.05.2006)
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Journal Article
Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination
Grosenbach, Douglas W, Jordan, Robert, King, David S, Berhanu, Aklile, Warren, Travis K, Kirkwood-Watts, Dana L, Tyavanagimatt, Shanthakumar, Tan, Ying, Wilson, Rebecca L, Jones, Kevin F, Hruby, Dennis E
Published in Vaccine (13.02.2008)
Published in Vaccine (13.02.2008)
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Treatment-enhanced CD4+Foxp3+ glucocorticoid-induced TNF receptor family related high regulatory tumor-infiltrating T cells limit the effectiveness of cytokine-based immunotherapy
Berhanu, Aklile, Huang, Jian, Watkins, Simon C, Okada, Hideho, Storkus, Walter J
Published in The Journal of immunology (1950) (15.03.2007)
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Published in The Journal of immunology (1950) (15.03.2007)
Journal Article
Treatment-Enhanced CD4 super(+)Foxp3 super(+) Glucocorticoid-Induced TNF Receptor Family Related super(High) Regulatory Tumor-Infiltrating T Cells Limit the Effectiveness of Cytokine-Based Immunotherapy
Berhanu, Aklile, Huang, Jian, Watkins, Simon C, Okada, Hideho, Storkus, Walter J
Published in Journal of Immunology (01.03.2007)
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Published in Journal of Immunology (01.03.2007)
Journal Article
Combinational Flt3 Ligand and Granulocyte Macrophage Colony-Stimulating Factor Treatment Promotes Enhanced Tumor Infiltration by Dendritic Cells and Antitumor CD8 super(+) T-Cell Cross-priming but Is Ineffective as a Therapy
Berhanu, Aklile, Huang, Jian, Alber, Sean M, Watkins, Simon C, Storkus, Walter J
Published in Cancer research (Chicago, Ill.) (01.05.2006)
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Published in Cancer research (Chicago, Ill.) (01.05.2006)
Journal Article
Treatment-Enhanced CD4+Foxp3+ Glucocorticoid-Induced TNF Receptor Family RelatedHigh Regulatory Tumor-Infiltrating T Cells Limit the Effectiveness of Cytokine-Based Immunotherapy
Berhanu, Aklile, Huang, Jian, Watkins, Simon C, Okada, Hideho, Storkus, Walter J
Published in The Journal of immunology (1950) (15.03.2007)
Published in The Journal of immunology (1950) (15.03.2007)
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Journal Article
Novel Small Molecule Inhibitors of Dengue Virus Replication
Byrd, Chelsea, Page, Jessica, Harver, Chris, Grosenbach, Doug, Berhanu, Aklile, Hruby, Dennis, Jordan, Robert
Published in Antiviral research (01.05.2009)
Published in Antiviral research (01.05.2009)
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