Differential antitumor activity of aflibercept and bevacizumab in patient-derived xenograft models of colorectal cancer
Chiron, Marielle, Bagley, Rebecca G, Pollard, Jack, Mankoo, Parminder K, Henry, Christophe, Vincent, Loïc, Geslin, Catherine, Baltes, Nina, Bergstrom, Donald A
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
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Journal Article
MyoD Targets Chromatin Remodeling Complexes to the Myogenin Locus Prior to Forming a Stable DNA-Bound Complex
de la Serna, Ivana L., Ohkawa, Yasuyuki, Berkes, Charlotte A., Bergstrom, Donald A., Dacwag, Caroline S., Tapscott, Stephen J., Imbalzano, Anthony N.
Published in Molecular and Cellular Biology (01.05.2005)
Published in Molecular and Cellular Biology (01.05.2005)
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Journal Article
Pbx Marks Genes for Activation by MyoD Indicating a Role for a Homeodomain Protein in Establishing Myogenic Potential
Berkes, Charlotte A, Bergstrom, Donald A, Penn, Bennett H, Seaver, Karen J, Knoepfler, Paul S, Tapscott, Stephen J
Published in Molecular cell (21.05.2004)
Published in Molecular cell (21.05.2004)
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Journal Article
Intrastrand Annealing Leads to the Formation of a Large DNA Palindrome and Determines the Boundaries of Genomic Amplification in Human Cancer
Tanaka, Hisashi, Cao, Yi, Bergstrom, Donald A., Kooperberg, Charles, Tapscott, Stephen J., Yao, Meng-Chao
Published in Molecular and Cellular Biology (01.03.2007)
Published in Molecular and Cellular Biology (01.03.2007)
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Journal Article
Dolaflexin: A Novel Antibody-Drug Conjugate Platform Featuring High Drug Loading and a Controlled Bystander Effect
Yurkovetskiy, Aleksandr V, Bodyak, Natalya D, Yin, Mao, Thomas, Joshua D, Clardy, Susan M, Conlon, Patrick R, Stevenson, Cheri A, Uttard, Alex, Qin, LiuLiang, Gumerov, Dmitry R, Ter-Ovanesyan, Elena, Bu, Charlie, Johnson, Alex J, Gurijala, Venu R, McGillicuddy, Dennis, DeVit, Michael J, Poling, Laura L, Protopopova, Marina, Xu, Ling, Zhang, Qingxiu, Park, Peter U, Bergstrom, Donald A, Lowinger, Timothy B
Published in Molecular cancer therapeutics (01.05.2021)
Published in Molecular cancer therapeutics (01.05.2021)
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Journal Article
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations
Subbiah, Vivek, Sahai, Vaibhav, Maglic, Dejan, Bruderek, Kamil, Touré, B Barry, Zhao, Songping, Valverde, Roberto, O'Hearn, Patrick J, Moustakas, Demetri T, Schönherr, Heike, Gerami-Moayed, Nastaran, Taylor, Alexander M, Hudson, Brandi M, Houde, Damian J, Pal, Debjani, Foster, Lindsey, Gunaydin, Hakan, Ayaz, Pelin, Sharon, Dina A, Goyal, Lipika, Schram, Alison M, Kamath, Suneel, Sherwin, Cori Ann, Schmidt-Kittler, Oleg, Jen, Kai Yu, Ricard, Fabien, Wolf, Beni B, Shaw, David E, Bergstrom, Donald A, Watters, James, Casaletto, Jessica B
Published in Cancer discovery (06.09.2023)
Published in Cancer discovery (06.09.2023)
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Journal Article
The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b
Bodyak, Natalya D, Mosher, Rebecca, Yurkovetskiy, Aleksandr V, Yin, Mao, Bu, Charlie, Conlon, Patrick R, Demady, Damon R, DeVit, Michael J, Gumerov, Dmitry R, Gurijala, Venu R, Lee, Winnie, McGillicuddy, Dennis, Park, Peter U, Poling, Laura L, Protopova, Marina, Qin, LiuLiang, Stevenson, Cheri A, Ter-Ovanesyan, Elena, Uttard, Alex, Xiao, Dongmei, Xu, Jian, Xu, Ling, Bergstrom, Donald A, Lowinger, Timothy B
Published in Molecular cancer therapeutics (01.05.2021)
Published in Molecular cancer therapeutics (01.05.2021)
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Journal Article
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2
Schönherr, Heike, Ayaz, Pelin, Taylor, Alexander M, Casaletto, Jessica B, Touré, B Barry, Moustakas, Demetri T, Hudson, Brandi M, Valverde, Roberto, Zhao, Songping, O'Hearn, Patrick J, Foster, Lindsey, Sharon, Dina A, Garfinkle, Sam, Giordanetto, Fabrizio, Lescarbeau, André, Kurukulasuriya, Ravi, Gerami-Moayed, Nastaran, Maglic, Dejan, Bruderek, Kamil, Naik, Gaauri, Gunaydin, Hakan, Mader, Mary M, Boezio, Alessandro A, McLean, Thomas H, Chen, Rongfeng, Wang, Yanxia, Shaw, David E, Watters, James, Bergstrom, Donald A
Published in Proceedings of the National Academy of Sciences - PNAS (06.02.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (06.02.2024)
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Journal Article
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
Varkaris, Andreas, Pazolli, Ermira, Gunaydin, Hakan, Wang, Qi, Pierce, Levi, Boezio, Alessandro A, Bulku, Artemisa, DiPietro, Lucian, Fridrich, Cary, Frost, Adam, Giordanetto, Fabrizio, Hamilton, Erika P, Harris, Katherine, Holliday, Michael, Hunter, Tamieka L, Iskandar, Amanda, Ji, Yongli, Larivée, Alexandre, LaRochelle, Jonathan R, Lescarbeau, André, Llambi, Fabien, Lormil, Brenda, Mader, Mary M, Mar, Brenton G, Martin, Iain, McLean, Thomas H, Michelsen, Klaus, Pechersky, Yakov, Puente-Poushnejad, Erika, Raynor, Kevin, Rogala, Dipali, Samadani, Ramin, Schram, Alison M, Shortsleeves, Kelley, Swaminathan, Sweta, Tajmir, Shahein, Tan, Gege, Tang, Yong, Valverde, Roberto, Wehrenberg, Bryan, Wilbur, Jeremy, Williams, Bret R, Zeng, Hongtao, Zhang, Hanmo, Walters, W Patrick, Wolf, Beni B, Shaw, David E, Bergstrom, Donald A, Watters, James, Fraser, James S, Fortin, Pascal D, Kipp, D Randal
Published in Cancer discovery (08.02.2024)
Published in Cancer discovery (08.02.2024)
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Journal Article
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
Luthi-Carter, Ruth, Hanson, Sarah A., Strand, Andrew D., Bergstrom, Donald A., Chun, Wanjoo, Peters, Nikki L., Woods, Annette M., Chan, Edmond Y., Kooperberg, Charles, Krainc, Dimitri, Young, Anne B., Tapscott, Stephen J., Olson, James M.
Published in Human molecular genetics (15.08.2002)
Published in Human molecular genetics (15.08.2002)
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Journal Article
Abstract 596: Optimization of lead antibody selection for XMT-1522, a novel, highly potent HER2-targeted antibody-drug conjugate (ADC)
Bodyak, Natasha, Yurkovetskiy, Alex, Gumerov, Dmitry R., Xiao, Dongmei, Thomas, Joshua D. Thomas D., Poling, Laura L., Qin, LiuLiang, Yin, Mao, DeVit, Michael J., Park, Peter U., Lee, Winnie, Prinz, Bianka, Bergstrom, Donald A., Lowinger, Timothy B.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Genome-wide analysis of palindrome formation
Tapscott, Stephen J, Diede, Scott J, Tanaka, Hisashi, Bergstrom, Donald A, Yao, Meng-Chao
Published in Nature genetics (01.04.2010)
Published in Nature genetics (01.04.2010)
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Journal Article
Participation of Cyclin A in Myc-Induced Apoptosis
Hoang, Arthur T., Cohen, Kenneth J., Barrett, John F., Bergstrom, Donald A., Dang, Chi V.
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.1994)
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