Accelerating Discovery of Functional Mutant Alleles in Cancer
Chang, Matthew T, Bhattarai, Tripti Shrestha, Schram, Alison M, Bielski, Craig M, Donoghue, Mark T A, Jonsson, Philip, Chakravarty, Debyani, Phillips, Sarah, Kandoth, Cyriac, Penson, Alexander, Gorelick, Alexander, Shamu, Tambudzai, Patel, Swati, Harris, Christopher, Gao, JianJiong, Sumer, Selcuk Onur, Kundra, Ritika, Razavi, Pedram, Li, Bob T, Reales, Dalicia N, Socci, Nicholas D, Jayakumaran, Gowtham, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria E, Chandarlapaty, Sarat, Ladanyi, Marc, Schultz, Nikolaus, Baselga, José, Berger, Michael F, Rosen, Neal, Solit, David B, Hyman, David M, Taylor, Barry S
Published in Cancer discovery (01.02.2018)
Published in Cancer discovery (01.02.2018)
Get full text
Journal Article
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Tang, Fanying, Xu, Duo, Wang, Shangqian, Wong, Chen Khuan, Martinez-Fundichely, Alexander, Lee, Cindy J, Cohen, Sandra, Park, Jane, Hill, Corinne E, Eng, Kenneth, Bareja, Rohan, Han, Teng, Liu, Eric Minwei, Palladino, Ann, Di, Wei, Gao, Dong, Abida, Wassim, Beg, Shaham, Puca, Loredana, Meneses, Maximiliano, de Stanchina, Elisa, Berger, Michael F, Gopalan, Anuradha, Dow, Lukas E, Mosquera, Juan Miguel, Beltran, Himisha, Sternberg, Cora N, Chi, Ping, Scher, Howard I, Sboner, Andrea, Chen, Yu, Khurana, Ekta
Published in Science (American Association for the Advancement of Science) (27.05.2022)
Published in Science (American Association for the Advancement of Science) (27.05.2022)
Get full text
Journal Article
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy
Chowell, Diego, Morris, Luc G T, Grigg, Claud M, Weber, Jeffrey K, Samstein, Robert M, Makarov, Vladimir, Kuo, Fengshen, Kendall, Sviatoslav M, Requena, David, Riaz, Nadeem, Greenbaum, Benjamin, Carroll, James, Garon, Edward, Hyman, David M, Zehir, Ahmet, Solit, David, Berger, Michael, Zhou, Ruhong, Rizvi, Naiyer A, Chan, Timothy A
Published in Science (American Association for the Advancement of Science) (02.02.2018)
Published in Science (American Association for the Advancement of Science) (02.02.2018)
Get full text
Journal Article
Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients
Yaeger, Rona, Cercek, Andrea, O'Reilly, Eileen M, Reidy, Diane L, Kemeny, Nancy, Wolinsky, Tamar, Capanu, Marinela, Gollub, Marc J, Rosen, Neal, Berger, Michael F, Lacouture, Mario E, Vakiani, Efsevia, Saltz, Leonard B
Published in Clinical cancer research (15.03.2015)
Published in Clinical cancer research (15.03.2015)
Get full text
Journal Article
Resistance to TRK inhibition mediated by convergent MAPK pathway activation
Cocco, Emiliano, Schram, Alison M., Kulick, Amanda, Misale, Sandra, Won, Helen H., Yaeger, Rona, Razavi, Pedram, Ptashkin, Ryan, Hechtman, Jaclyn F., Toska, Eneda, Cownie, James, Somwar, Romel, Shifman, Sophie, Mattar, Marissa, Selçuklu, S. Duygu, Samoila, Aliaksandra, Guzman, Sean, Tuch, Brian B., Ebata, Kevin, de Stanchina, Elisa, Nagy, Rebecca J., Lanman, Richard B., Houck-Loomis, Brian, Patel, Juber A., Berger, Michael F., Ladanyi, Marc, Hyman, David M., Drilon, Alexander, Scaltriti, Maurizio
Published in Nature medicine (01.09.2019)
Published in Nature medicine (01.09.2019)
Get full text
Journal Article
Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping
Paik, Paul K, Drilon, Alexander, Fan, Pang-Dian, Yu, Helena, Rekhtman, Natasha, Ginsberg, Michelle S, Borsu, Laetitia, Schultz, Nikolaus, Berger, Michael F, Rudin, Charles M, Ladanyi, Marc
Published in Cancer discovery (01.08.2015)
Published in Cancer discovery (01.08.2015)
Get full text
Journal Article
Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase
Valero, Cristina, Lee, Mark, Hoen, Douglas, Zehir, Ahmet, Berger, Michael F, Seshan, Venkatraman E, Chan, Timothy A, Morris, Luc G T
Published in JAMA oncology (01.05.2021)
Published in JAMA oncology (01.05.2021)
Get more information
Journal Article
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo
Wei, Gong-Hong, Badis, Gwenael, Berger, Michael F, Kivioja, Teemu, Palin, Kimmo, Enge, Martin, Bonke, Martin, Jolma, Arttu, Varjosalo, Markku, Gehrke, Andrew R, Yan, Jian, Talukder, Shaheynoor, Turunen, Mikko, Taipale, Mikko, Stunnenberg, Hendrik G, Ukkonen, Esko, Hughes, Timothy R, Bulyk, Martha L, Taipale, Jussi
Published in The EMBO journal (07.07.2010)
Published in The EMBO journal (07.07.2010)
Get full text
Journal Article
Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer
Latham, Alicia, Srinivasan, Preethi, Kemel, Yelena, Shia, Jinru, Bandlamudi, Chaitanya, Mandelker, Diana, Middha, Sumit, Hechtman, Jaclyn, Zehir, Ahmet, Dubard-Gault, Marianne, Tran, Christina, Stewart, Carolyn, Sheehan, Margaret, Penson, Alexander, DeLair, Deborah, Yaeger, Rona, Vijai, Joseph, Mukherjee, Semanti, Galle, Jesse, Dickson, Mark A, Janjigian, Yelena, O'Reilly, Eileen M, Segal, Neil, Saltz, Leonard B, Reidy-Lagunes, Diane, Varghese, Anna M, Bajorin, Dean, Carlo, Maria I, Cadoo, Karen, Walsh, Michael F, Weiser, Martin, Aguilar, Julio Garcia, Klimstra, David S, Diaz, Jr, Luis A, Baselga, Jose, Zhang, Liying, Ladanyi, Marc, Hyman, David M, Solit, David B, Robson, Mark E, Taylor, Barry S, Offit, Kenneth, Berger, Michael F, Stadler, Zsofia K
Published in Journal of clinical oncology (01.02.2019)
Published in Journal of clinical oncology (01.02.2019)
Get full text
Journal Article
Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma
Audenet, François, Isharwal, Sumit, Cha, Eugene K, Donoghue, Mark T A, Drill, Esther N, Ostrovnaya, Irina, Pietzak, Eugene J, Sfakianos, John P, Bagrodia, Aditya, Murugan, Paari, Dalbagni, Guido, Donahue, Timothy F, Rosenberg, Jonathan E, Bajorin, Dean F, Arcila, Maria E, Hechtman, Jaclyn F, Berger, Michael F, Taylor, Barry S, Al-Ahmadie, Hikmat, Iyer, Gopa, Bochner, Bernard H, Coleman, Jonathan A, Solit, David B
Published in Clinical cancer research (01.02.2019)
Published in Clinical cancer research (01.02.2019)
Get full text
Journal Article
Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid
Miller, Alexandra M., Shah, Ronak H., Pentsova, Elena I., Pourmaleki, Maryam, Briggs, Samuel, Distefano, Natalie, Zheng, Youyun, Skakodub, Anna, Mehta, Smrutiben A., Campos, Carl, Hsieh, Wan-Ying, Selcuklu, S. Duygu, Ling, Lilan, Meng, Fanli, Jing, Xiaohong, Samoila, Aliaksandra, Bale, Tejus A., Tsui, Dana W. Y., Grommes, Christian, Viale, Agnes, Souweidane, Mark M., Tabar, Viviane, Brennan, Cameron W., Reiner, Anne S., Rosenblum, Marc, Panageas, Katherine S., DeAngelis, Lisa M., Young, Robert J., Berger, Michael F., Mellinghoff, Ingo K.
Published in Nature (London) (01.01.2019)
Published in Nature (London) (01.01.2019)
Get full text
Journal Article
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
De Mattos-Arruda, Leticia, Mayor, Regina, Ng, Charlotte K. Y., Weigelt, Britta, Martínez-Ricarte, Francisco, Torrejon, Davis, Oliveira, Mafalda, Arias, Alexandra, Raventos, Carolina, Tang, Jiabin, Guerini-Rocco, Elena, Martínez-Sáez, Elena, Lois, Sergio, Marín, Oscar, de la Cruz, Xavier, Piscuoglio, Salvatore, Towers, Russel, Vivancos, Ana, Peg, Vicente, Ramon y Cajal, Santiago, Carles, Joan, Rodon, Jordi, González-Cao, María, Tabernero, Josep, Felip, Enriqueta, Sahuquillo, Joan, Berger, Michael F., Cortes, Javier, Reis-Filho, Jorge S., Seoane, Joan
Published in Nature communications (10.11.2015)
Published in Nature communications (10.11.2015)
Get full text
Journal Article
Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials
Hyman, David M., Solit, David B., Arcila, Maria E., Cheng, Donavan T., Sabbatini, Paul, Baselga, Jose, Berger, Michael F., Ladanyi, Marc
Published in Drug discovery today (01.12.2015)
Published in Drug discovery today (01.12.2015)
Get full text
Journal Article
A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2- Metastatic Breast Cancer
Mayer, Ingrid A, Abramson, Vandana G, Formisano, Luigi, Balko, Justin M, Estrada, Mónica V, Sanders, Melinda E, Juric, Dejan, Solit, David, Berger, Michael F, Won, Helen H, Li, Yisheng, Cantley, Lewis C, Winer, Eric, Arteaga, Carlos L
Published in Clinical cancer research (01.01.2017)
Published in Clinical cancer research (01.01.2017)
Get full text
Journal Article
Tumour lineage shapes BRCA-mediated phenotypes
Jonsson, Philip, Bandlamudi, Chaitanya, Cheng, Michael L., Srinivasan, Preethi, Chavan, Shweta S., Friedman, Noah D., Rosen, Ezra Y., Richards, Allison L., Bouvier, Nancy, Selcuklu, S. Duygu, Bielski, Craig M., Abida, Wassim, Mandelker, Diana, Birsoy, Ozge, Zhang, Liying, Zehir, Ahmet, Donoghue, Mark T. A., Baselga, José, Offit, Kenneth, Scher, Howard I., O’Reilly, Eileen M., Stadler, Zsofia K., Schultz, Nikolaus, Socci, Nicholas D., Viale, Agnes, Ladanyi, Marc, Robson, Mark E., Hyman, David M., Berger, Michael F., Solit, David B., Taylor, Barry S.
Published in Nature (London) (01.07.2019)
Published in Nature (London) (01.07.2019)
Get full text
Journal Article
PD-1 Blockade in Advanced Adrenocortical Carcinoma
Raj, Nitya, Zheng, Youyun, Kelly, Virginia, Katz, Seth S, Chou, Joanne, Do, Richard K G, Capanu, Marinela, Zamarin, Dmitriy, Saltz, Leonard B, Ariyan, Charlotte E, Untch, Brian R, O'Reilly, Eileen M, Gopalan, Anuradha, Berger, Michael F, Olino, Kelly, Segal, Neil H, Reidy-Lagunes, Diane L
Published in Journal of clinical oncology (01.01.2020)
Published in Journal of clinical oncology (01.01.2020)
Get full text
Journal Article
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers
Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José
Published in Cancer cell (10.09.2018)
Published in Cancer cell (10.09.2018)
Get full text
Journal Article
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology
Cheng, Donavan T, Mitchell, Talia N, Zehir, Ahmet, Shah, Ronak H, Benayed, Ryma, Syed, Aijazuddin, Chandramohan, Raghu, Liu, Zhen Yu, Won, Helen H, Scott, Sasinya N, Brannon, A Rose, O'Reilly, Catherine, Sadowska, Justyna, Casanova, Jacklyn, Yannes, Angela, Hechtman, Jaclyn F, Yao, Jinjuan, Song, Wei, Ross, Dara S, Oultache, Alifya, Dogan, Snjezana, Borsu, Laetitia, Hameed, Meera, Nafa, Khedoudja, Arcila, Maria E, Ladanyi, Marc, Berger, Michael F
Published in The Journal of molecular diagnostics : JMD (01.05.2015)
Published in The Journal of molecular diagnostics : JMD (01.05.2015)
Get full text
Journal Article