The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety
Ho, Ginny D., Anthes, John, Bercovici, Ana, Caldwell, John P., Cheng, Kuo-Chi, Cui, Xiaoming, Fawzi, Ahmad, Fernandez, Xiomara, Greenlee, William J., Hey, John, Korfmacher, Walter, Lu, Sherry X., McLeod, Robbie L., Ng, Fay, Torhan, April Smith, Tan, Zheng, Tulshian, Deen, Varty, Geoffrey B., Xu, Xiaoying, Zhang, Hongtao
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Journal Article
Discovery of pyrrolo-benzo-1,4-diazines as potent Nav1.7 sodium channel blockers
Ho, Ginny D., Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Heap, Charles R., Earley, William G., Courneya, Brandy, Jason Herr, R., Zhou, Xiaoping, Bridal, Terry, Rindgen, Diane, Sorota, Steve, Yang, Shu-Wei
Published in Bioorganic & medicinal chemistry letters (01.09.2014)
Published in Bioorganic & medicinal chemistry letters (01.09.2014)
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Journal Article
Bioavailable pyrrolo-benzo-1,4-diazines as Nav1.7 sodium channel blockers for the treatment of pain
Yang, Shu-Wei, Ho, Ginny D., Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Sun, Xianfeng, Sakwa, Samuel A., Herr, R. Jason, Zhou, Xiaoping, Bridal, Terry, Urban, Mark, Vivian, Jeffrey, Rindgen, Diane, Sorota, Steve
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
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Journal Article
Bioavailable pyrrolo-benzo-1,4-diazines as Na(v)1.7 sodium channel blockers for the treatment of pain
Yang, Shu-Wei, Ho, Ginny D., Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Sun, Xianfeng, Sakwa, Samuel A., Herr, R. Jason, Zhou, Xiaoping, Bridal, Terry, Urban, Mark, Vivian, Jeffrey, Rindgen, Diane, Sorota, Steve
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
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Journal Article
The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia
Ho, Ginny D., Yang, Shu-Wei, Smotryski, Jennifer, Bercovici, Ana, Nechuta, Terry, Smith, Elizabeth M., McElroy, William, Tan, Zheng, Tulshian, Deen, McKittrick, Brian, Greenlee, William J., Hruza, Alan, Xiao, Li, Rindgen, Diane, Mullins, Deborra, Guzzi, Mario, Zhang, Xiaoping, Bleickardt, Carina, Hodgson, Robert
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Journal Article
The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia
Ho, Ginny D., Michael Seganish, W., Bercovici, Ana, Tulshian, Deen, Greenlee, William J., Van Rijn, Rachel, Hruza, Alan, Xiao, Li, Rindgen, Diane, Mullins, Deborra, Guzzi, Mario, Zhang, Xiaoping, Bleickardt, Carina, Hodgson, Robert
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Journal Article
Discovery of pyrrolo-benzo-1,4-diazines as potent Na(v)1.7 sodium channel blockers
Ho, Ginny D., Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Heap, Charles R., Earley, William G., Courneya, Brandy, Herr, R. Jason, Zhou, Xiaoping, Bridal, Terry, Rindgen, Diane, Sorota, Steve, Yang, Shu-Wei
Published in Bioorganic & medicinal chemistry letters (01.09.2014)
Published in Bioorganic & medicinal chemistry letters (01.09.2014)
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Journal Article
Bioavailable pyrrolo-benzo-1,4-diazines as Na sub(v)1.7 sodium channel blockers for the treatment of pain
Yang, Shu-Wei, Ho, Ginny D, Tulshian, Deen, Bercovici, Ana, Tan, Zheng, Hanisak, Jennifer, Brumfield, Stephanie, Matasi, Julius, Sun, Xianfeng, Sakwa, Samuel A, Herr, RJason, Zhou, Xiaoping, Bridal, Terry, Urban, Mark, Vivian, Jeffrey, Rindgen, Diane, Sorota, Steve
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
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Journal Article
The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): Comparison of efficacy and side effects across rodent species
Lu, Sherry X., Higgins, Guy A., Hodgson, Robert A., Hyde, Lynn A., Del Vecchio, Robert A., Guthrie, Donald H., Kazdoba, Tatiana, McCool, Martha F., Morgan, Cynthia A., Bercovici, Ana, Ho, Ginny D., Tulshian, Deen, Parker, Eric M., Hunter, John C., Varty, Geoffrey B.
Published in European journal of pharmacology (01.07.2011)
Published in European journal of pharmacology (01.07.2011)
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Journal Article
The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]oct a ne-3-carboxamide (SCH 655842): Comparison of efficacy and side effects across rodent species
Lu, Sherry X, Higgins, Guy A, Hodgson, Robert A, Hyde, Lynn A, Del Vecchio, Robert A, Guthrie, Donald H, Kazdoba, Tatiana, McCool, Martha F, Morgan, Cynthia A, Bercovici, Ana, Ho, Ginny D, Tulshian, Deen, Parker, Eric M, Hunter, John C, Varty, Geoffrey B
Published in European journal of pharmacology (01.07.2011)
Published in European journal of pharmacology (01.07.2011)
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Journal Article
Synthesis and structure–activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2
Ho, Ginny D., Bercovici, Ana, Tulshian, Deen, Greenlee, William J., Fawzi, Ahmad, Fernandez, Xiomara, McLeod, Robbie L., Smith Torhan, April, Zhang, Hongtao
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Journal Article
Synthesis and structure–activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1
Ho, Ginny D., Bercovici, Ana, Tulshian, Deen, Greenlee, William J., Fawzi, Ahmad, Smith Torhan, April, Zhang, Hongtao
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Journal Article
Potent Tetracyclic Guanine Inhibitors of PDE1 and PDE5 Cyclic Guanosine Monophosphate Phosphodiesterases with Oral Antihypertensive Activity
Ahn, Ho-Sam, Bercovici, Ana, Boykow, George, Bronnenkant, Alan, Chackalamannil, Samuel, Chow, Jason, Cleven, Renee, Cook, John, Czarniecki, Michael, Domalski, Carol, Fawzi, Ahmad, Green, Michael, Gündes, Asli, Ho, Ginny, Laudicina, Malvina, Lindo, Neil, Ma, Ke, Manna, Mahua, McKittrick, Brian, Mirzai, Bita, Nechuta, Terry, Neustadt, Bernard, Puchalski, Chester, Pula, Kathryn, Silverman, Lisa, Smith, Elizabeth, Stamford, Andrew, Tedesco, Richard P, Tsai, Hsingan, Tulshian, Deen, Vaccaro, Henry, Watkins, Robert W, Weng, Xiaoyu, Witkowski, Joseph T, Xia, Yan, Zhang, Hongtao
Published in Journal of medicinal chemistry (04.07.1997)
Published in Journal of medicinal chemistry (04.07.1997)
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Journal Article
Synthesis and evaluation of potent and selective c-GMP phosphodiesterase inhibitors
Ho, Ginny Dai, Lisa, Silverman, Bercovici, Ana, Puchalski, Chester, Tulshian, Deen, Xia, Yan, Czarniecki, Michael, Green, Michael, Cleven, Renee, Zhang, Hongtao, Fawzi, Ahmad
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
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Journal Article
ChemInform Abstract: A Synthesis of Dihydroimidazo[5,1-a]isoquinolines Using a Sequential Ugi-Bischler-Napieralski Reaction Sequence
Seganish, W. Michael, Bercovici, Ana, Ho, Ginny D., Loozen, Hubert J. J., Timmers, Cornelis M., Tulshian, Deen
Published in ChemInform (12.06.2012)
Published in ChemInform (12.06.2012)
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"AGONISTAS DO RECEPTOR ORL-1 DE NOCICEPTINA, COMPOSIÇÕES FARMACÊUTICAS COMPREENDENDO OS MESMOS E SEUS USOS NA FABRICAÇÃO DE MEDICAMENTOS"
FRANCIS M. CUSS, LISA S. SILVERMAN, JULIUS J. MATASI, RICHARD W. CHAPMAN, ANA BERCOVICI, JOHN A. HEY, ROBBIE L. MCLEOD, DEEN TULSHIAN, GINNY D. HO
Year of Publication 22.10.2013
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Year of Publication 22.10.2013
Patent
High affinity ligands for nociceptin receptor ORL-1
HO GINNY D, TULSHIAN DEEN, BERCOVICI ANA, SAWUTZ DAVID G, BRIANCEAU PHILIPPE
Year of Publication 03.02.2009
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Year of Publication 03.02.2009
Patent
High affinity ligands for nociceptin receptor ORL-1
Sawutz, David G, Brianceau, Philippe, Bercovici, Ana, Ho, Ginny D, Tulshian, Deen
Year of Publication 03.02.2009
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Year of Publication 03.02.2009
Patent