The Mechanism of Anti-PD-L1 Antibody Efficacy against PD-L1-Negative Tumors Identifies NK Cells Expressing PD-L1 as a Cytolytic Effector
Dong, Wenjuan, Wu, Xiaojin, Ma, Shoubao, Wang, Yufeng, Nalin, Ansel P, Zhu, Zheng, Zhang, Jianying, Benson, Don M, He, Kai, Caligiuri, Michael A, Yu, Jianhua
Published in Cancer discovery (01.10.2019)
Published in Cancer discovery (01.10.2019)
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Journal Article
Fratricide of NK Cells in Daratumumab Therapy for Multiple Myeloma Overcome by Ex Vivo -Expanded Autologous NK Cells
Wang, Yufeng, Zhang, Yibo, Hughes, Tiffany, Zhang, Jianying, Caligiuri, Michael A, Benson, Don M, Yu, Jianhua
Published in Clinical cancer research (15.08.2018)
Published in Clinical cancer research (15.08.2018)
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Journal Article
A phase 1b study of isatuximab plus lenalidomide and dexamethasone for relapsed/refractory multiple myeloma
Martin, Thomas, Baz, Rachid, Benson, Don M., Lendvai, Nikoletta, Wolf, Jeffrey, Munster, Pamela, Lesokhin, Alexander M., Wack, Claudine, Charpentier, Eric, Campana, Frank, Vij, Ravi
Published in Blood (22.06.2017)
Published in Blood (22.06.2017)
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Journal Article
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody
Benson, Don M., Bakan, Courtney E., Mishra, Anjali, Hofmeister, Craig C., Efebera, Yvonne, Becknell, Brian, Baiocchi, Robert A., Zhang, Jianying, Yu, Jianhua, Smith, Megan K., Greenfield, Carli N., Porcu, Pierluigi, Devine, Steven M., Rotem-Yehudar, Rinat, Lozanski, Gerard, Byrd, John C., Caligiuri, Michael A.
Published in Blood (30.09.2010)
Published in Blood (30.09.2010)
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Journal Article
TTK/MPS1 inhibitor OSU-13 targets the mitotic checkpoint and is a potential therapeutic strategy for myeloma
Longo, Larissa Valle Guilhen, Hughes, Tiffany, McNeil-Laidley, Betina, Cottini, Francesca, Hilinski, Gerard, Merritt, Elizabeth, Benson, Don M
Published in Haematologica (Roma) (01.02.2024)
Published in Haematologica (Roma) (01.02.2024)
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Journal Article
Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: evidence for augmented NK cell function complementing ADCC
Collins, Shauna M., Bakan, Courtney E., Swartzel, Gina D., Hofmeister, Craig C., Efebera, Yvonne A., Kwon, Hakju, Starling, Gary C., Ciarlariello, David, Bhaskar, Shakthi, Briercheck, Edward L., Hughes, Tiffany, Yu, Jianhua, Rice, Audie, Benson, Don M.
Published in Cancer Immunology, Immunotherapy (01.12.2013)
Published in Cancer Immunology, Immunotherapy (01.12.2013)
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Journal Article
The IL-15–AKT–XBP1s signaling pathway contributes to effector functions and survival in human NK cells
Wang, Yufeng, Zhang, Yibo, Yi, Ping, Dong, Wenjuan, Nalin, Ansel P., Zhang, Jianying, Zhu, Zheng, Chen, Lichao, Benson, Don M., Mundy-Bosse, Bethany L., Freud, Aharon G., Caligiuri, Michael A., Yu, Jianhua
Published in Nature immunology (01.01.2019)
Published in Nature immunology (01.01.2019)
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Journal Article
IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect
Benson, Don M., Bakan, Courtney E., Zhang, Shuhong, Collins, Shauna M., Liang, Jing, Srivastava, Shivani, Hofmeister, Craig C., Efebera, Yvonne, Andre, Pascale, Romagne, Francois, Bléry, Mathieu, Bonnafous, Cécile, Zhang, Jianying, Clever, David, Caligiuri, Michael A., Farag, Sherif S.
Published in Blood (08.12.2011)
Published in Blood (08.12.2011)
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Journal Article
Phase I Trial of Anti-CS1 Monoclonal Antibody Elotuzumab in Combination With Bortezomib in the Treatment of Relapsed/Refractory Multiple Myeloma
JAKUBOWIAK, Andrzej J, BENSON, Don M, BENSINGER, William, SIEGEL, David S. D, ZIMMERMAN, Todd M, MOHRBACHER, Ann, RICHARDSON, Paul G, AFAR, Daniel E. H, SINGHAL, Anil K, ANDERSON, Kenneth C
Published in Journal of clinical oncology (01.06.2012)
Published in Journal of clinical oncology (01.06.2012)
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Journal Article
A Phase I Trial of the Anti-KIR Antibody IPH2101 and Lenalidomide in Patients with Relapsed/Refractory Multiple Myeloma
Benson, Jr, Don M, Cohen, Adam D, Jagannath, Sundar, Munshi, Nikhil C, Spitzer, Gary, Hofmeister, Craig C, Efebera, Yvonne A, Andre, Pascale, Zerbib, Robert, Caligiuri, Michael A
Published in Clinical cancer research (15.09.2015)
Published in Clinical cancer research (15.09.2015)
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Journal Article
The Transcription Factor AHR Prevents the Differentiation of a Stage 3 Innate Lymphoid Cell Subset to Natural Killer Cells
Hughes, Tiffany, Briercheck, Edward L., Freud, Aharon G., Trotta, Rossana, McClory, Susan, Scoville, Steven D., Keller, Karen, Deng, Youcai, Cole, Jordan, Harrison, Nicholas, Mao, Charlene, Zhang, Jianying, Benson, Don M., Yu, Jianhua, Caligiuri, Michael A.
Published in Cell reports (Cambridge) (10.07.2014)
Published in Cell reports (Cambridge) (10.07.2014)
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Journal Article
Hedgehog-induced PD-L1 on tumor-associated macrophages is critical for suppression of tumor-infiltrating CD8+ T cell function
Petty, Amy J, Dai, Rui, Lapalombella, Rosa, Baiocchi, Robert A, Benson, Don M, Li, Zihai, Huang, Xiaopei, Yang, Yiping
Published in JCI insight (22.03.2021)
Published in JCI insight (22.03.2021)
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Journal Article
A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma
Benson, Don M., Hofmeister, Craig C., Padmanabhan, Swaminathan, Suvannasankha, Attaya, Jagannath, Sundar, Abonour, Rafat, Bakan, Courtney, Andre, Pascale, Efebera, Yvonne, Tiollier, Jérôme, Caligiuri, Michael A., Farag, Sherif S.
Published in Blood (22.11.2012)
Published in Blood (22.11.2012)
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Journal Article
Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers
Harshman, Sean W., Canella, Alessandro, Ciarlariello, Paul D., Agarwal, Kitty, Branson, Owen E., Rocci, Alberto, Cordero, Hector, Phelps, Mitch A., Hade, Erinn M., Dubovsky, Jason A., Palumbo, Antonio, Rosko, Ashley, Byrd, John C., Hofmeister, Craig C., Benson, Don M., Paulaitis, Michael E., Freitas, Michael A., Pichiorri, Flavia
Published in Journal of proteomics (16.03.2016)
Published in Journal of proteomics (16.03.2016)
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Journal Article
Survival outcomes following autologous stem cell transplant with melphalan 140mg/m2 versus 200mg/m2 preparative regimens in patients with multiple myeloma
Sharma, Nidhi, Benson, Evan, Zhao, Qiuhong, Nunnelee, Jordan, Cottini, Francesca, Elder, Patrick, Rosko, Ashley, Bumma, Naresh, Khan, Abdullah, Umyarova, Elvira, Devarakonda, Srinivas, Efebera, Yvonne A., Benson, Don M.
Published in Leukemia & lymphoma (01.07.2023)
Published in Leukemia & lymphoma (01.07.2023)
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Journal Article
Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells
Romagné, Francois, André, Pascale, Spee, Pieter, Zahn, Stefan, Anfossi, Nicolas, Gauthier, Laurent, Capanni, Marusca, Ruggeri, Loredana, Benson, Don M., Blaser, Bradley W., Della Chiesa, Mariella, Moretta, Alessandro, Vivier, Eric, Caligiuri, Michael A., Velardi, Andrea, Wagtmann, Nicolai
Published in Blood (24.09.2009)
Published in Blood (24.09.2009)
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Journal Article
A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells
Lin, Li, Benson Jr, Don M., DeAngelis, Stephanie, Bakan, Courtney E., Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Published in International journal of cancer (15.03.2012)
Published in International journal of cancer (15.03.2012)
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