Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia
Hudkins, Robert L., Allen, Eric, Balcer, Alexandra, Hoffman, Isaac D., Iyer, Samhita, Neal, Melissa, Nelson, Kirk J., Rideout, Marc, Ye, Qing, Starrett, Jacqueline H., Patel, Piyush, Harris, Todd, Swanson, Ronald V., Bensen, Daniel C.
Published in Journal of medicinal chemistry (26.09.2024)
Published in Journal of medicinal chemistry (26.09.2024)
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Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents
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Published in PloS one (26.12.2013)
Published in PloS one (26.12.2013)
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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity
Tari, Leslie W., Trzoss, Michael, Bensen, Daniel C., Li, Xiaoming, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Creighton, Christopher J., Cunningham, Mark L., Kwan, Bryan, Stidham, Mark, Shaw, Karen J., Lightstone, Felice C., Wong, Sergio E., Nguyen, Toan B., Nix, Jay, Finn, John
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity
Trzoss, Micheal, Bensen, Daniel C., Li, Xiaoming, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Creighton, Christopher J., Cunningham, Mark L., Kwan, Bryan, Stidham, Mark, Nelson, Kirk, Brown-Driver, Vickie, Castellano, Amanda, Shaw, Karen J., Lightstone, Felice C., Wong, Sergio E., Nguyen, Toan B., Finn, John, Tari, Leslie W.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Distinguishing on-target versus off-target activity in early antibacterial drug discovery using a macromolecular synthesis assay
Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Bensen, Daniel C, Shaw, Karen J
Published in Journal of biomolecular screening (01.10.2013)
Published in Journal of biomolecular screening (01.10.2013)
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Comparative Genomic Analysis of Archaeal Genotypic Variants in a Single Population and in Two Different Oceanic Provinces
BEJA, Oded, KOONIN, Eugene V, ARAVIND, L, TAYLOR, Lance T, SEITZ, Heidi, STEIN, Jefferey L, BENSEN, Daniel C, FELDMAN, Robert A, SWANSON, Ronald V, DELONG, Edward F
Published in Applied and Environmental Microbiology (01.01.2002)
Published in Applied and Environmental Microbiology (01.01.2002)
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Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors
Tari, Leslie W., Hoffman, Isaac D., Bensen, Daniel C., Hunter, Michael J., Nix, Jay, Nelson, Kirk J., McRee, Duncan E., Swanson, Ronald V.
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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바이러스 감염의 치료를 위한 조성물 및 방법
DO QUYEN QUYEN THUY, BORCHARDT ALLEN, CHEN ZHI YONG, BALKOVEC JAMES M, JIANG WANLONG, COLE JASON, DOEHRMANN SIMON, LAM THANH, BENSEN DANIEL C, BRADY THOMAS P, NONCOVICH ALAIN, TARI LESLIE W
Year of Publication 27.06.2022
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Year of Publication 27.06.2022
Patent
바이러스 감염의 치료를 위한 조성물 및 방법
DO QUYEN QUYEN THUY, BORCHARDT ALLEN, CHEN ZHI YONG, BALKOVEC JAMES M, JIANG WANLONG, COLE JASON, DOEHRMANN SIMON, LAM THANH, BENSEN DANIEL C, BRADY THOMAS P, NONCOVICH ALAIN, TARI LESLIE W
Year of Publication 29.06.2021
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Year of Publication 29.06.2021
Patent
TRICYCLIC GYRASE INHIBITORS
LEE SUK JOONG, CHEN ZHIYONG, LI XIAOMING, ZHANG JUNHU, WONG SERGIO E, LAM THANH TO, NGUYEN TOAN B, BENSEN DANIEL, TRZOSS MICHAEL, ARISTOFF PAUL, LIGHTSTONE FELICE, PHILLIPSON DOUGLAS W, FINN JOHN, TARI LESLIE WILLIAM, JUNG MICHAEL
Year of Publication 10.09.2019
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Year of Publication 10.09.2019
Patent