Discovery of a chemical probe for PRDM9
Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud
Published in Nature communications (17.12.2019)
Published in Nature communications (17.12.2019)
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Journal Article
Dysphagia and soft-tissue swelling after anterior cervical surgery: a radiographic analysis
Kepler, Christopher K., MD, MBA, Rihn, Jeffrey A., MD, Bennett, Jonathan D., BS, Anderson, David G., MD, Vaccaro, Alexander R., MD, PhD, Albert, Todd J., MD, Hilibrand, Alan S., MD
Published in The spine journal (01.08.2012)
Published in The spine journal (01.08.2012)
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Journal Article
Cyclodextrin-Derived Host Molecules as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide: Synthesis and Structure−Activity Relationships
Adam, Julia M, Bennett, D. Jonathan, Bom, Anton, Clark, John K, Feilden, Helen, Hutchinson, Edward J, Palin, Ronald, Prosser, Alan, Rees, David C, Rosair, Georgina M, Stevenson, Donald, Tarver, Gary J, Zhang, Ming-Qiang
Published in Journal of medicinal chemistry (25.04.2002)
Published in Journal of medicinal chemistry (25.04.2002)
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Journal Article
Rapid Detection of Significant Traumatic Brain Injury Requiring Emergency Intervention
Howley, Isaac W., Bennett, Jonathan D., Stein, Deborah M.
Published in The American surgeon (01.09.2021)
Published in The American surgeon (01.09.2021)
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Journal Article
6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors
Cai, Jiaqiang, Baugh, Mark, Black, Darcey, Long, Clive, Jonathan Bennett, D., Dempster, Maureen, Fradera, Xavier, Gillespie, Jonathan, Andrews, Fiona, Boucharens, Sylviane, Bruin, John, Cameron, Kenneth S., Cumming, Iain, Hamilton, William, Jones, Philip S., Kaptein, Allard, Kinghorn, Emma, Maidment, Maurice, Martin, Iain, Mitchell, Ann, Rankovic, Zoran, Robinson, John, Scullion, Paul, Uitdehaag, Joost C.M., Vink, Paul, Westwood, Paul, van Zeeland, Mario, van Berkom, Leon, Bastiani, Martijn, Meulemans, Tommi
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Identification and in Vivo Evaluation of Liver X Receptor β‑Selective Agonists for the Potential Treatment of Alzheimer’s Disease
Stachel, Shawn J, Zerbinatti, Celina, Rudd, Michael T, Cosden, Mali, Suon, Sokreine, Nanda, Kausik K, Wessner, Keith, DiMuzio, Jillian, Maxwell, Jill, Wu, Zhenhua, Uslaner, Jason M, Michener, Maria S, Szczerba, Peter, Brnardic, Edward, Rada, Vanessa, Kim, Yuntae, Meissner, Robert, Wuelfing, Peter, Yuan, Yang, Ballard, Jeanine, Holahan, Marie, Klein, Daniel J, Lu, Jun, Fradera, Xavier, Parthasarathy, Gopal, Uebele, Victor N, Chen, Zhongguo, Li, Yingjie, Li, Jian, Cooke, Andrew J, Bennett, D. Jonathan, Bilodeau, Mark T, Renger, John
Published in Journal of medicinal chemistry (14.04.2016)
Published in Journal of medicinal chemistry (14.04.2016)
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Journal Article
Detecting direct oral anticoagulants in trauma patients using liquid chromatography-mass spectrometry: A novel approach to medication reconciliation
Jayaraman, Sudha, DeAntonio, Jonathan H, Leichtle, Stefan W, Han, Jinfeng, Liebrecht, Loren, Contaifer, Daniel, Young, Caroline, Chou, Christopher, Staschen, Julia, Doan, David, Kumar, Naren Gajenthra, Wolfe, Luke, Nguyen, Tammy, Chenault, Gregory, Anand, Rahul J, Bennett, Jonathan D, Ferrada, Paula, Goldberg, Stephanie, Procter, Levi D, Rodas, Edgar B, Rossi, Alan P, Whelan, James F, Feeser, Ventaka Ramana, Vitto, Michael J, Broering, Beth, Hobgood, Sarah, Mangino, Martin, Aboutanos, Michel, Bachmann, Lorin, Wijesinghe, Dayanjan S
Published in The journal of trauma and acute care surgery (01.04.2020)
Published in The journal of trauma and acute care surgery (01.04.2020)
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Journal Article
Imidazopyridyl compounds as aldosterone synthase inhibitors
Whitehead, Brent R., Lo, Michael M.-C., Ali, Amjad, Park, Min K., Hoyt, Scott B., Xiong, Yusheng, Cai, Jiaqiang, Carswell, Emma, Cooke, Andrew, MacLean, John, Ratcliffe, Paul, Robinson, John, Bennett, D. Jonathan, Clemas, Joseph A., Wisniewski, Tom, Struthers, Mary, Cully, Doris, MacNeil, Douglas J.
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
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Journal Article
Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys
Hoyt, Scott B, Park, Min K, London, Clare, Xiong, Yusheng, Tata, Jim, Bennett, D. Jonathan, Cooke, Andrew, Cai, Jiaqiang, Carswell, Emma, Robinson, John, MacLean, John, Brown, Lindsay, Belshaw, Simone, Clarkson, Thomas R, Liu, Kun, Liang, Gui-Bai, Struthers, Mary, Cully, Doris, Wisniewski, Tom, Ren, Ning, Bopp, Charlene, Sok, Andrea, Cai, Tian-Quan, Stribling, Sloan, Pai, Lee-Yuh, Ma, Xiuying, Metzger, Joe, Verras, Andreas, McMasters, Daniel, Chen, Qing, Tung, Elaine, Tang, Wei, Salituro, Gino, Buist, Nicole, Kuethe, Jeff, Rivera, Nelo, Clemas, Joe, Zhou, Gaochao, Gibson, Jack, Maxwell, Carrie Ann, Lassman, Mike, McLaughlin, Theresa, Castro-Perez, Jose, Szeto, Daphne, Forrest, Gail, Hajdu, Richard, Rosenbach, Mark, Ali, Amjad
Published in ACS medicinal chemistry letters (14.05.2015)
Published in ACS medicinal chemistry letters (14.05.2015)
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Journal Article
Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors
Cai, Jiaqiang, Robinson, John, Belshaw, Simone, Everett, Kathryn, Fradera, Xavier, van Zeeland, Mario, van Berkom, Leon, van Rijnsbergen, Peter, Popplestone, Lucy, Baugh, Mark, Dempster, Maureen, Bruin, John, Hamilton, William, Kinghorn, Emma, Westwood, Paul, Kerr, Jennifer, Rankovic, Zoran, Arbuckle, Wullie, Bennett, D. Jonathan, Jones, Philip S., Long, Clive, Martin, Iain, Uitdehaag, Joost C.M., Meulemans, Tommi
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
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Journal Article
4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important
Cai, Jiaqiang, Fradera, Xavier, van Zeeland, Mario, Dempster, Maureen, Cameron, Kenneth S., Bennett, D. Jonathan, Robinson, John, Popplestone, Lucy, Baugh, Mark, Westwood, Paul, Bruin, John, Hamilton, William, Kinghorn, Emma, Long, Clive, Uitdehaag, Joost C.M.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
1H-Imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: Separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pkₐ
Arbuckle, Wullie, Baugh, Mark, Belshaw, Simone, Bennett, D. Jonathan, Bruin, John, Cai, Jiaqiang, Cameron, Kenneth S, Claxton, Chris, Dempster, Maureen, Everett, Kathryn, Fradera, Xavier, Hamilton, William, Jones, Philip S, Kinghorn, Emma, Long, Clive, Martin, Iain, Robinson, John, Westwood, Paul
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
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Journal Article
2-Phenyl-9H-purine-6-carbonitrile derivatives as selective cathepsin S inhibitors
Cai, Jiaqiang, Bennett, D. Jonathan, Rankovic, Zoran, Dempster, Maureen, Fradera, Xavier, Gillespie, Jonathan, Cumming, Iain, Finlay, William, Baugh, Mark, Boucharens, Sylviane, Bruin, John, Cameron, Kenneth S., Hamilton, William, Kerr, Jennifer, Kinghorn, Emma, McGarry, George, Robinson, John, Scullion, Paul, Uitdehaag, Joost C.M., van Zeeland, Mario, Potin, Dominique, Saniere, Laurent, Fouquet, Andre, Chevallier, Francois, Deronzier, Hortense, Dorleans, Cecile, Nicolai, Eric
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Novel water soluble 2,6-dimethoxyphenyl ester derivatives with intravenous anaesthetic activity
Bennett, D.Jonathan, Anderson, Alison, Buchanan, Kirsteen, Byford, Alan, Cooke, Andrew, Gemmell, David K., Hamilton, Niall M., Maidment, Maurice S., McPhail, Petula, Stevenson, Donald F.M., Sundaram, Hardy, Vijn, Peter
Published in Bioorganic & medicinal chemistry letters (16.06.2003)
Published in Bioorganic & medicinal chemistry letters (16.06.2003)
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Journal Article
Comparing Management Strategies for Traumatic Femoral Artery Injuries: Five-Year Experience at a Single Level I Trauma Center
Gaston, Brandon T., Rodas, Edgar B., Leichtle, Stefan W., Albuquerque, Francisco B., Bennett, Jonathan D., Larson, Robert A., Aboutanos, Michel B., Levy, Mark M.
Published in Journal of the American College of Surgeons (01.10.2019)
Published in Journal of the American College of Surgeons (01.10.2019)
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Journal Article
X-Ray Structures of the LXRα LBD in Its Homodimeric Form and Implications for Heterodimer Signaling
Fradera, Xavier, Vu, Diep, Nimz, Olaf, Skene, Robert, Hosfield, David, Wynands, Robert, Cooke, Andrew J., Haunsø, Anders, King, Angela, Bennett, D. Jonathan, McGuire, Ross, Uitdehaag, Joost C.M.
Published in Journal of molecular biology (28.05.2010)
Published in Journal of molecular biology (28.05.2010)
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Journal Article
1 H-Imidazo[4,5- c]pyridine-4-carbonitrile as cathepsin S inhibitors: Separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen p k a
Arbuckle, Wullie, Baugh, Mark, Belshaw, Simone, Bennett, D. Jonathan, Bruin, John, Cai, Jiaqiang, Cameron, Kenneth S., Claxton, Chris, Dempster, Maureen, Everett, Kathryn, Fradera, Xavier, Hamilton, William, Jones, Philip S., Kinghorn, Emma, Long, Clive, Martin, Iain, Robinson, John, Westwood, Paul
Published in Bioorganic & medicinal chemistry letters (2011)
Published in Bioorganic & medicinal chemistry letters (2011)
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Journal Article
Stereoselectivity in reactions of atropisomeric lactams and imides
Bennett, D.Jonathan, Blake, Alexander J, Cooke, Paul A, Godfrey, Christopher R.A, Pickering, Paula L, Simpkins, Nigel S, Walker, Matthew D, Wilson, Claire
Published in Tetrahedron (10.05.2004)
Published in Tetrahedron (10.05.2004)
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Journal Article
Extracellular Volume Fraction Associates with Long-term Outcome in Patients with Severe Symptomatic Aortic Stenosis: 9 Year Outcome of the RELIEF-AS Study
Aziminia, Nikoo, Thornton, George, Bennett, Jonathan, Chadalavada, Sucharitha, Pierce, Iain, Kellman, Peter, Davies, Rhodri, Manisty, Charlotte, Moon, James, Treibel, Thomas
Published in Journal of cardiovascular magnetic resonance (2024)
Published in Journal of cardiovascular magnetic resonance (2024)
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Journal Article