Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
Briggs, Kimberly J., Koivunen, Peppi, Cao, Shugeng, Backus, Keriann M., Olenchock, Benjamin A., Patel, Hetalben, Zhang, Qing, Signoretti, Sabina, Gerfen, Gary J., Richardson, Andrea L., Witkiewicz, Agnieszka K., Cravatt, Benjamin F., Clardy, Jon, Kaelin, William G.
Published in Cell (30.06.2016)
Published in Cell (30.06.2016)
Get full text
Journal Article
A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles
Wang, Chu, Weerapana, Eranthie, Blewett, Megan M, Cravatt, Benjamin F
Published in Nature methods (01.01.2014)
Published in Nature methods (01.01.2014)
Get full text
Journal Article
Global profiling of lysine reactivity and ligandability in the human proteome
Hacker, Stephan M., Backus, Keriann M., Lazear, Michael R., Forli, Stefano, Correia, Bruno E., Cravatt, Benjamin F.
Published in Nature chemistry (01.12.2017)
Published in Nature chemistry (01.12.2017)
Get full text
Journal Article
Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study
Simon, Gabriel M., Cravatt, Benjamin F.
Published in The Journal of biological chemistry (09.04.2010)
Published in The Journal of biological chemistry (09.04.2010)
Get full text
Journal Article
Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries
Kuljanin, Miljan, Mitchell, Dylan C., Schweppe, Devin K., Gikandi, Ajami S., Nusinow, David P., Bulloch, Nathan J., Vinogradova, Ekaterina V., Wilson, David L., Kool, Eric T., Mancias, Joseph D., Cravatt, Benjamin F., Gygi, Steven P.
Published in Nature biotechnology (01.05.2021)
Published in Nature biotechnology (01.05.2021)
Get full text
Journal Article
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers
Villa, Genaro R., Hulce, Jonathan J., Zanca, Ciro, Bi, Junfeng, Ikegami, Shiro, Cahill, Gabrielle L., Gu, Yuchao, Lum, Kenneth M., Masui, Kenta, Yang, Huijun, Rong, Xin, Hong, Cynthia, Turner, Kristen M., Liu, Feng, Hon, Gary C., Jenkins, David, Martini, Michael, Armando, Aaron M., Quehenberger, Oswald, Cloughesy, Timothy F., Furnari, Frank B., Cavenee, Webster K., Tontonoz, Peter, Gahman, Timothy C., Shiau, Andrew K., Cravatt, Benjamin F., Mischel, Paul S.
Published in Cancer cell (14.11.2016)
Published in Cancer cell (14.11.2016)
Get full text
Journal Article
Activity-based protein profiling for biochemical pathway discovery in cancer
Cravatt, Benjamin F, Nomura, Daniel K, Dix, Melissa M
Published in Nature reviews. Cancer (01.09.2010)
Published in Nature reviews. Cancer (01.09.2010)
Get full text
Journal Article
Ligand and Target Discovery by Fragment-Based Screening in Human Cells
Parker, Christopher G., Galmozzi, Andrea, Wang, Yujia, Correia, Bruno E., Sasaki, Kenji, Joslyn, Christopher M., Kim, Arthur S., Cavallaro, Cullen L., Lawrence, R. Michael, Johnson, Stephen R., Narvaiza, Iñigo, Saez, Enrique, Cravatt, Benjamin F.
Published in Cell (26.01.2017)
Published in Cell (26.01.2017)
Get full text
Journal Article
Global profiling of dynamic protein palmitoylation
Martin, Brent R, Wang, Chu, Adibekian, Alexander, Tully, Sarah E, Cravatt, Benjamin F
Published in Nature methods (01.01.2012)
Published in Nature methods (01.01.2012)
Get full text
Journal Article
Global profiling of phosphorylation-dependent changes in cysteine reactivity
Kemper, Esther K., Zhang, Yuanjin, Dix, Melissa M., Cravatt, Benjamin F.
Published in Nature methods (01.03.2022)
Published in Nature methods (01.03.2022)
Get full text
Journal Article
Quantitative reactivity profiling predicts functional cysteines in proteomes
Cravatt, Benjamin F, Weerapana, Eranthie, Wang, Chu, Simon, Gabriel M, Richter, Florian, Khare, Sagar, Dillon, Myles B. D, Bachovchin, Daniel A, Mowen, Kerri, Baker, David
Published in Nature (London) (09.12.2010)
Published in Nature (London) (09.12.2010)
Get full text
Journal Article
Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells
Hulce, Jonathan J, Cognetta, Armand B, Niphakis, Micah J, Tully, Sarah E, Cravatt, Benjamin F
Published in Nature methods (01.03.2013)
Published in Nature methods (01.03.2013)
Get full text
Journal Article
A proteome-wide atlas of lysine-reactive chemistry
Abbasov, Mikail E., Kavanagh, Madeline E., Ichu, Taka-Aki, Lazear, Michael R., Tao, Yongfeng, Crowley, Vincent M., am Ende, Christopher W., Hacker, Stephan M., Ho, Jordan, Dix, Melissa M., Suciu, Radu, Hayward, Matthew M., Kiessling, Laura L., Cravatt, Benjamin F.
Published in Nature chemistry (01.11.2021)
Published in Nature chemistry (01.11.2021)
Get full text
Journal Article
Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
Bi, Junfeng, Ichu, Taka-Aki, Zanca, Ciro, Yang, Huijun, Zhang, Wei, Gu, Yuchao, Chowdhry, Sudhir, Reed, Alex, Ikegami, Shiro, Turner, Kristen M., Zhang, Wenjing, Villa, Genaro R., Wu, Sihan, Quehenberger, Oswald, Yong, William H., Kornblum, Harley I., Rich, Jeremy N., Cloughesy, Timothy F., Cavenee, Webster K., Furnari, Frank B., Cravatt, Benjamin F., Mischel, Paul S.
Published in Cell metabolism (03.09.2019)
Published in Cell metabolism (03.09.2019)
Get full text
Journal Article