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Published in The Journal of immunology (1950) (01.05.2019)
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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
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Published in Nature structural & molecular biology (01.08.2023)
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Redirecting the pioneering function of FOXA1 with covalent small molecules
Won, Sang Joon, Zhang, Yuxiang, Reinhardt, Christopher J., Hargis, Lauren M., MacRae, Nicole S., DeMeester, Kristen E., Njomen, Evert, Remsberg, Jarrett R., Melillo, Bruno, Cravatt, Benjamin F., Erb, Michael A.
Published in Molecular cell (07.11.2024)
Published in Molecular cell (07.11.2024)
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Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells
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Published in Nature chemistry (01.10.2024)
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Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders
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Published in Journal of the American Chemical Society (17.04.2024)
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Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator
Mizrak, Dogukan, Bayin, N. Sumru, Yuan, Jinzhou, Liu, Zhouzerui, Suciu, Radu M., Niphakis, Micah J., Ngo, Nhi, Lum, Kenneth M., Cravatt, Benjamin F., Joyner, Alexandra L., Sims, Peter A.
Published in Cell reports (Cambridge) (23.06.2020)
Published in Cell reports (Cambridge) (23.06.2020)
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The Sleep-Inducing Lipid Oleamide Deconvolutes Gap Junction Communication and Calcium Wave Transmission in Glial Cells
Guan, Xiaojun, Cravatt, Benjamin F., Ehring, George R., Hall, James E., Boger, Dale L., Lerner, Richard A., Gilula, Norton B.
Published in The Journal of cell biology (29.12.1997)
Published in The Journal of cell biology (29.12.1997)
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Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan
Chen, Alice L., Lum, Kenneth M., Lara-Gonzalez, Pablo, Ogasawara, Daisuke, Cognetta, Armand B, To, Alan, Parsons, William H., Simon, Gabriel M., Desai, Arshad, Petrascheck, Michael, Bar-Peled, Liron, Cravatt, Benjamin F.
Published in Nature chemical biology (01.05.2019)
Published in Nature chemical biology (01.05.2019)
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Proteomic discovery of chemical probes that perturb protein complexes in human cells
Lazear, Michael R., Remsberg, Jarrett R., Jaeger, Martin G., Rothamel, Katherine, Her, Hsuan-lin, DeMeester, Kristen E., Njomen, Evert, Hogg, Simon J., Rahman, Jahan, Whitby, Landon R., Won, Sang Joon, Schafroth, Michael A., Ogasawara, Daisuke, Yokoyama, Minoru, Lindsey, Garrett L., Li, Haoxin, Germain, Jason, Barbas, Sabrina, Vaughan, Joan, Hanigan, Thomas W., Vartabedian, Vincent F., Reinhardt, Christopher J., Dix, Melissa M., Koo, Seong Joo, Heo, Inha, Teijaro, John R., Simon, Gabriel M., Ghosh, Brahma, Abdel-Wahab, Omar, Ahn, Kay, Saghatelian, Alan, Melillo, Bruno, Schreiber, Stuart L., Yeo, Gene W., Cravatt, Benjamin F.
Published in Molecular cell (18.05.2023)
Published in Molecular cell (18.05.2023)
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An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes
Zhang, Yuanjin, Liu, Zhonglin, Hirschi, Marscha, Brodsky, Oleg, Johnson, Eric, Won, Sang Joon, Nagata, Asako, Bezwada, Divya, Petroski, Matthew D, Majmudar, Jaimeen D, Niessen, Sherry, VanArsdale, Todd, Gilbert, Adam M, Hayward, Matthew M, Stewart, Al E, Nager, Andrew R, Melillo, Bruno, Cravatt, Benjamin F
Published in Nature chemical biology (18.09.2024)
Published in Nature chemical biology (18.09.2024)
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Fatty acid amide hydrolase gene inactivation induces hetero-cellular potentiation of microglial function in the 5xFAD mouse model of Alzheimer's disease
Arnanz, María Andrea, Ferrer, María, Grande, María Teresa, de Martín Esteban, Samuel Ruiz, Ruiz-Pérez, Gonzalo, Cravatt, Benjamin F, Mostany, Ricardo, Lobo, Víctor Javier Sánchez-Arévalo, Romero, Julián, Martínez-Relimpio, Ana María
Published in Glia (30.10.2024)
Published in Glia (30.10.2024)
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(−)-FR182877 Is a Potent and Selective Inhibitor of Carboxylesterase-1
Adam, Gregory C., Vanderwal, Christopher D., Sorensen, Erik J., Cravatt, Benjamin F.
Published in Angewandte Chemie International Edition (17.11.2003)
Published in Angewandte Chemie International Edition (17.11.2003)
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Proteome-wide mapping of PQS-interacting proteins in Pseudomonas aeruginosa
Dandela, Rambabu, Mantin, Danielle, Cravatt, Benjamin F., Rayo, Josep, Meijler, Michael M.
Published in Chemical science (Cambridge) (28.02.2018)
Published in Chemical science (Cambridge) (28.02.2018)
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