C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis
Faravelli, Giulia, Raimondi, Sara, Marchese, Loredana, Partridge, Frederick A., Soria, Cristina, Mangione, P. Patrizia, Canetti, Diana, Perni, Michele, Aprile, Francesco A., Zorzoli, Irene, Di Schiavi, Elia, Lomas, David A., Bellotti, Vittorio, Sattelle, David B., Giorgetti, Sofia
Published in Scientific reports (27.12.2019)
Published in Scientific reports (27.12.2019)
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Journal Article
Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils
Giorgetti, Sofia, Raimondi, Sara, Pagano, Katiuscia, Relini, Annalisa, Bucciantini, Monica, Corazza, Alessandra, Fogolari, Federico, Codutti, Luca, Salmona, Mario, Mangione, Palma, Colombo, Lino, De Luigi, Ada, Porcari, Riccardo, Gliozzi, Alessandra, Stefani, Massimo, Esposito, Gennaro, Bellotti, Vittorio, Stoppini, Monica
Published in The Journal of biological chemistry (01.01.2011)
Published in The Journal of biological chemistry (01.01.2011)
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Journal Article
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes
Sartiani, Laura, Bucciantini, Monica, Spinelli, Valentina, Leri, Manuela, Natalello, Antonino, Nosi, Daniele, Maria Doglia, Silvia, Relini, Annalisa, Penco, Amanda, Giorgetti, Sofia, Gerace, Elisabetta, Mannaioni, Guido, Bellotti, Vittorio, Rigacci, Stefania, Cerbai, Elisabetta, Stefani, Massimo
Published in Biophysical journal (01.11.2016)
Published in Biophysical journal (01.11.2016)
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Journal Article
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis
Rezk, Tamer, Gilbertson, Janet A, Mangione, P Patrizia, Rowczenio, Dorota, Rendell, Nigel B, Canetti, Diana, Lachmann, Helen J, Wechalekar, Ashutosh D, Bass, Paul, Hawkins, Philip N, Bellotti, Vittorio, Taylor, Graham W, Gillmore, Julian D
Published in The journal of pathology. Clinical research (01.07.2019)
Published in The journal of pathology. Clinical research (01.07.2019)
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Journal Article
Amyloidogenic and Associated Proteins in Systemic Amyloidosis Proteome of Adipose Tissue
Lavatelli, Francesca, Perlman, David H., Spencer, Brian, Prokaeva, Tatiana, McComb, Mark E., Théberge, Roger, Connors, Lawreen H., Bellotti, Vittorio, Seldin, David C., Merlini, Giampaolo, Skinner, Martha, Costello, Catherine E.
Published in Molecular & cellular proteomics (01.08.2008)
Published in Molecular & cellular proteomics (01.08.2008)
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Journal Article
Calcium Binds to Transthyretin with Low Affinity
Cantarutti, Cristina, Mimmi, Maria Chiara, Verona, Guglielmo, Mandaliti, Walter, Taylor, Graham W, Mangione, P. Patrizia, Giorgetti, Sofia, Bellotti, Vittorio, Corazza, Alessandra
Published in Biomolecules (Basel, Switzerland) (02.08.2022)
Published in Biomolecules (Basel, Switzerland) (02.08.2022)
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Journal Article
Heparin Strongly Enhances the Formation of β2-Microglobulin Amyloid Fibrils in the Presence of Type I Collagen
Relini, Annalisa, De Stefano, Silvia, Torrassa, Silvia, Cavalleri, Ornella, Rolandi, Ranieri, Gliozzi, Alessandra, Giorgetti, Sofia, Raimondi, Sara, Marchese, Loredana, Verga, Laura, Rossi, Antonio, Stoppini, Monica, Bellotti, Vittorio
Published in The Journal of biological chemistry (22.02.2008)
Published in The Journal of biological chemistry (22.02.2008)
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Journal Article
Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans
Raimondi, Sara, Faravelli, Giulia, Nocerino, Paola, Mondani, Valentina, Baruffaldi, Alma, Marchese, Loredana, Mimmi, Maria Chiara, Canetti, Diana, Verona, Guglielmo, Caterino, Marianna, Ruoppolo, Margherita, Mangione, P Patrizia, Bellotti, Vittorio, Lavatelli, Francesca, Giorgetti, Sofia
Published in FASEB bioAdvances (01.11.2023)
Published in FASEB bioAdvances (01.11.2023)
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Journal Article
Collagen Plays an Active Role in the Aggregation of β2-Microglobulin under Physiopathological Conditions of Dialysis-related Amyloidosis
Relini, Annalisa, Canale, Claudio, De Stefano, Silvia, Rolandi, Ranieri, Giorgetti, Sofia, Stoppini, Monica, Rossi, Antonio, Fogolari, Federico, Corazza, Alessandra, Esposito, Gennaro, Gliozzi, Alessandra, Bellotti, Vittorio
Published in The Journal of biological chemistry (16.06.2006)
Published in The Journal of biological chemistry (16.06.2006)
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Journal Article
The Protein Network in Subcutaneous Fat Biopsies from Patients with AL Amyloidosis: More Than Diagnosis?
Di Silvestre, Dario, Brambilla, Francesca, Lavatelli, Francesca, Chirivì, Maila, Canetti, Diana, Bearzi, Claudia, Rizzi, Roberto, Bijzet, Johan, Hazenberg, Bouke P C, Bellotti, Vittorio, Gillmore, Julian D, Mauri, Pierluigi
Published in Cells (Basel, Switzerland) (22.02.2023)
Published in Cells (Basel, Switzerland) (22.02.2023)
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Journal Article
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo
Raimondi, Sara, Porcari, Riccardo, Mangione, P. Patrizia, Verona, Guglielmo, Marcoux, Julien, Giorgetti, Sofia, Taylor, Graham W., Ellmerich, Stephan, Ballico, Maurizio, Zanini, Stefano, Pardon, Els, Al-Shawi, Raya, Simons, J. Paul, Corazza, Alessandra, Fogolari, Federico, Leri, Manuela, Stefani, Massimo, Bucciantini, Monica, Gillmore, Julian D., Hawkins, Philip N., Valli, Maurizia, Stoppini, Monica, Robinson, Carol V., Steyaert, Jan, Esposito, Gennaro, Bellotti, Vittorio
Published in Scientific reports (21.04.2017)
Published in Scientific reports (21.04.2017)
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Journal Article
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms
Faravelli, Giulia, Mondani, Valentina, Mangione, P Patrizia, Raimondi, Sara, Marchese, Loredana, Lavatelli, Francesca, Stoppini, Monica, Corazza, Alessandra, Canetti, Diana, Verona, Guglielmo, Obici, Laura, Taylor, Graham W, Gillmore, Julian D, Giorgetti, Sofia, Bellotti, Vittorio
Published in Frontiers in molecular biosciences (14.02.2022)
Published in Frontiers in molecular biosciences (14.02.2022)
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Journal Article
Native-unlike Long-lived Intermediates along the Folding Pathway of the Amyloidogenic Protein β2-Microglobulin Revealed by Real-time Two-dimensional NMR
Corazza, Alessandra, Rennella, Enrico, Schanda, Paul, Mimmi, Maria Chiara, Cutuil, Thomas, Raimondi, Sara, Giorgetti, Sofia, Fogolari, Federico, Viglino, Paolo, Frydman, Lucio, Gal, Maayan, Bellotti, Vittorio, Brutscher, Bernhard, Esposito, Gennaro
Published in The Journal of biological chemistry (19.02.2010)
Published in The Journal of biological chemistry (19.02.2010)
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Journal Article
Structure, function and amyloidogenic propensity of apolipoprotein A-I
Obici, Laura, Franceschini, Guido, Calabresi, Laura, Giorgetti, Sofia, Stoppini, Monica, Merlini, Giampaolo, Bellotti, Vittorio
Published in Amyloid (01.12.2006)
Published in Amyloid (01.12.2006)
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Journal Article
The Controlling Roles of Trp60 and Trp95 in β2-Microglobulin Function, Folding and Amyloid Aggregation Properties
Esposito, Gennaro, Ricagno, Stefano, Corazza, Alessandra, Rennella, Enrico, Gümral, Devrim, Mimmi, Maria Chiara, Betto, Elena, Pucillo, Carlo E.M., Fogolari, Federico, Viglino, Paolo, Raimondi, Sara, Giorgetti, Sofia, Bolognesi, Benedetta, Merlini, Giampaolo, Stoppini, Monica, Bolognesi, Martino, Bellotti, Vittorio
Published in Journal of molecular biology (01.05.2008)
Published in Journal of molecular biology (01.05.2008)
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Journal Article
Trapping of palindromic ligands within native transthyretin prevents amyloid formation
Kolstoe, Simon E., Mangione, Palma P., Bellotti, Vittorio, Taylor, Graham W., Tennent, Glenys A., Deroo, Stéphanie, Morrison, Angus J., Cobb, Alexander J. A., Coyne, Anthony, McCammon, Margaret G., Warner, Timothy D., Mitchell, Jane, Gill, Raj, Smith, Martin D., Ley, Steven V., Robinson, Carol V., Wood, Stephen P., Pepys, Mark B., Weatherall, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2010)
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Journal Article
Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β2-Microglobulin
Halabelian, Levon, Ricagno, Stefano, Giorgetti, Sofia, Santambrogio, Carlo, Barbiroli, Alberto, Pellegrino, Sara, Achour, Adnane, Grandori, Rita, Marchese, Loredana, Raimondi, Sara, Mangione, P. Patrizia, Esposito, Gennaro, Al-Shawi, Raya, Simons, J. Paul, Speck, Ivana, Stoppini, Monica, Bolognesi, Martino, Bellotti, Vittorio
Published in The Journal of biological chemistry (07.02.2014)
Published in The Journal of biological chemistry (07.02.2014)
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Journal Article
Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component
Ozawa, Daisaku, Nomura, Ryo, Mangione, P. Patrizia, Hasegawa, Kazuhiro, Okoshi, Tadakazu, Porcari, Riccardo, Bellotti, Vittorio, Naiki, Hironobu
Published in Amyloid (16.03.2017)
Published in Amyloid (16.03.2017)
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Journal Article
Reconstruction of Massive Posterior Nonrepairable Acetabular Labral Tears With Peroneus Brevis Tendon Allograft: Arthroscopy-Assisted Mini-Open Approach
Moya, Esther, M.D, Natera, Luis Gerardo, M.D, Cardenas, Carlomagno, M.D, Astarita, Emanuele, M.D, Bellotti, Vittorio, M.D, Ribas, Manel, M.D
Published in Arthroscopy techniques (Amsterdam) (01.10.2016)
Published in Arthroscopy techniques (Amsterdam) (01.10.2016)
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