ProteInfer, deep neural networks for protein functional inference
Sanderson, Theo, Bileschi, Maxwell L, Belanger, David, Colwell, Lucy J
Published in eLife (27.02.2023)
Published in eLife (27.02.2023)
Get full text
Journal Article
Rapid Prediction of Electron–Ionization Mass Spectrometry Using Neural Networks
Wei, Jennifer N, Belanger, David, Adams, Ryan P, Sculley, D
Published in ACS central science (24.04.2019)
Published in ACS central science (24.04.2019)
Get full text
Journal Article
Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study
Rich, Alexander S., Chan, Yvonne H., Birnbaum, Benjamin, Haider, Kamran, Haimson, Joshua, Hale, Michael, Han, Yongxin, Hickman, William, Hoeflich, Klaus P., Ortwine, Daniel, Özen, Ayşegül, Belanger, David B.
Published in ACS medicinal chemistry letters (08.08.2024)
Published in ACS medicinal chemistry letters (08.08.2024)
Get full text
Journal Article
Synthesizing Normalized Faces from Facial Identity Features
Cole, Forrester, Belanger, David, Krishnan, Dilip, Sarna, Aaron, Mosseri, Inbar, Freeman, William T.
Published in 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) (01.07.2017)
Published in 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) (01.07.2017)
Get full text
Conference Proceeding
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway
Karki, Rajeshri G, Powers, James, Mainolfi, Nello, Anderson, Karen, Belanger, David B, Liu, Donglei, Ji, Nan, Jendza, Keith, Gelin, Christine F, Mac Sweeney, Aengus, Solovay, Catherine, Delgado, Omar, Crowley, Maura, Liao, Sha-Mei, Argikar, Upendra A, Flohr, Stefanie, La Bonte, Laura R, Lorthiois, Edwige L, Vulpetti, Anna, Brown, Ann, Long, Debby, Prentiss, Melissa, Gradoux, Nathalie, de Erkenez, Andrea, Cumin, Frederic, Adams, Christopher, Jaffee, Bruce, Mogi, Muneto
Published in Journal of medicinal chemistry (09.05.2019)
Published in Journal of medicinal chemistry (09.05.2019)
Get full text
Journal Article
Lithothamnion (Hapalidiales, Rhodophyta) in the changing Arctic and Subarctic: DNA sequencing of type and recent specimens provides a systematics foundation
Peña, Viviana, Bélanger, David, Gagnon, Patrick, Richards, Joseph L., Le Gall, Line, Hughey, Jeffery R., Saunders, Gary W., Lindstrom, Sandra C., Rinde, Eli, Husa, Vivian, Christie, Hartvig, Fredriksen, Stein, Hall-Spencer, Jason M., Steneck, Robert S., Schoenrock, Kathryn M., Gitmark, Janne, Grefsrud, Ellen Sofie, Anglès d'Auriac, Marc B., Legrand, Erwann, Grall, Jacques, Mumford, Thomas F., Kamenos, Nicholas A., Gabrielson, Paul W.
Published in European journal of phycology (2021)
Published in European journal of phycology (2021)
Get full text
Journal Article
The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma
Ehara, Takeru, Adams, Christopher M, Bevan, Doug, Ji, Nan, Meredith, Erik L, Belanger, David B, Powers, James, Kato, Mitsunori, Solovay, Catherine, Liu, Donglei, Capparelli, Michael, Bolduc, Philippe, Grob, Jonathan E, Daniels, Matthew H, Ferrara, Luciana, Yang, Louis, Li, Byron, Towler, Christopher S, Stacy, Rebecca C, Prasanna, Ganesh, Mogi, Muneto
Published in Journal of medicinal chemistry (22.03.2018)
Published in Journal of medicinal chemistry (22.03.2018)
Get full text
Journal Article
Discovery of a highly potent orally bioavailable imidazo-[1, 2-a]pyrazine Aurora inhibitor
Yu, Tao, Zhang, Yonglian, Kerekes, Angela D., Tagat, Jayaram R., Doll, Ronald J., Xiao, Yushi, Esposite, Sara, Hruza, Alan, Belanger, David B., Voss, Matthew, Rainka, Matthew P., Basso, Andrea, Liu, Ming, Liang, Lianzhu, Sui, Ning, Prelusky, Daniel, Rindgen, Diane, Zhang, Likang
Published in Bioorganic & medicinal chemistry letters (01.05.2018)
Published in Bioorganic & medicinal chemistry letters (01.05.2018)
Get full text
Journal Article
Discovery of imidazo[1,2- a]pyrazine-based Aurora kinase inhibitors
Belanger, David B., Curran, Patrick J., Hruza, Alan, Voigt, Johannes, Meng, Zhaoyang, Mandal, Amit K., Siddiqui, M. Arshad, Basso, Andrea D., Gray, Kimberly
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Get full text
Journal Article
Discovery of novel imidazo[1,2- a]pyrazin-8-amines as Brk/PTK6 inhibitors
Zeng, Hongbo, Belanger, David B., Curran, Patrick J., Shipps, Gerald W., Miao, Hua, Bracken, Jack B., Arshad Siddiqui, M., Malkowski, Michael, Wang, Yan
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Get full text
Journal Article
Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivity
Voss, Matthew E., Rainka, Matthew P., Fleming, Mike, Peterson, Lisa H., Belanger, David B., Siddiqui, M. Arshad, Hruza, Alan, Voigt, Johannes, Gray, Kimberly, Basso, Andrea D.
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
Get full text
Journal Article
Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitors
Meng, Zhaoyang, Kulkarni, Bheemashankar A., Kerekes, Angela D., Mandal, Amit K., Esposite, Sara J., Belanger, David B., Reddy, Panduranga Adulla, Basso, Andrea D., Tevar, Seema, Gray, Kimberly, Jones, Jennifer, Smith, Elizabeth B., Doll, Ronald J., Siddiqui, M. Arshad
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Get full text
Journal Article
Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core
Yu, Tao, Tagat, Jayaram R, Kerekes, Angela D, Doll, Ronald J, Zhang, Yonglian, Xiao, Yushi, Esposite, Sara, Belanger, David B, Curran, Patrick J, Mandal, Amit K, Siddiqui, M. Arshad, Shih, Neng-Yang, Basso, Andrea D, Liu, Ming, Gray, Kimberly, Tevar, Seema, Jones, Jennifer, Lee, Suining, Liang, Lianzhu, Ponery, Samad, Smith, Elizabeth B, Hruza, Alan, Voigt, Johannes, Ramanathan, Lata, Prosise, Winifred, Hu, Mengwei
Published in ACS medicinal chemistry letters (12.08.2010)
Published in ACS medicinal chemistry letters (12.08.2010)
Get full text
Journal Article
Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors
Belanger, David B., Williams, Michael J., Curran, Patrick J., Mandal, Amit K., Meng, Zhaoyang, Rainka, Matthew P., Yu, Tao, Shih, Neng-Yang, Siddiqui, M. Arshad, Liu, Ming, Tevar, Seema, Lee, Suining, Liang, Lianzhu, Gray, Kimberly, Yaremko, Bohdan, Jones, Jennifer, Smith, Elizabeth B., Prelusky, Dan B., Basso, Andrea D.
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Get full text
Journal Article
The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors
Rosner, Kristin E., Guo, Zhuyan, Orth, Peter, Shipps, Gerald W., Belanger, David B., Chan, Tin Yau, Curran, Patrick J., Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M., Hong, Liwu, Lavey, Brian J., Lee, Joe F., Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C., Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng -Yang, Arshad Siddiqui, M., Strickland, Corey O.
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Get full text
Journal Article