A phase Ib trial with MK-8628/OTX015, a small molecule inhibitor of bromodomain (BRD) and extra-terminal (BET) proteins, in patients with selected advanced solid tumors
Massard, C, Soria, J.C, Stathis, A, Delord, J.P, Awada, A, Peters, S, Lewin, J, Bekradda, M, Rezai, K, Zeng, Z, Azher, H, Perez, S, Siu, L
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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469 OTX015, a novel BET-bromodomain (BET-BRD) inhibitor, is a promising anticancer agent for human glioblastoma
Ouafik, L, Berenguer, C, Cayol, M, Astorgues-Xerri, L, Bekradda, M, Odore, E, Rezai, K, Riveiro, M.E, Cvitkovic, E
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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567 OTX015, a BET-bromodomain (BET-BRD) inhibitor, potentiates the in vitro effects of chemotherapy drugs and targeted agents in human leukemic cell lines
Astorgues-Xerri, L, Canet-Jourdan, C, Bekradda, M, Cvitkovic, E, Herait, P, Raymond, E, Riveiro, M
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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587 Cellular pharmacokinetics and molecular pharmacodynamics studies of the BRD-BET inhibitor OTX015 in sensitive and resistant leukemic cell lines
Odore, E, Astorgues-Xerri, L, Bekradda, M, Cvitkovic, E, Herait, P, Lokiec, F, Rezai, K, Riveiro, M
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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564 OTX015, a novel BET-BRD inhibitor is active in non-small-cell lung cancer cell (NSCLC) lines harboring different oncogenic mutations
Riveiro, M, Astorgues-Xerri, L, Ijaz, N, Bekradda, M, Vazquez, R, Frapolli, R, Rinaldi, A, Kwee, I, Cvitkovic, E, Raymond, E
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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580 Evaluation of the pan-BET-bromodomain inhibitor OTX015 as a single agent and in combination with everolimus (RAD001) in triple-negative breast cancer models
Vázquez, R, Astorgues-Xerri, L, Riveiro, M.E, Di Marino, M, Beltrame, L, Bekradda, M, Cvitkovic, E, Erba, E, Frapolli, R, D'Incalci, M
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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An open phase II trial of gemcitabine, oxaliplatin and vinorelbine combination as first-line therapy in advanced non-small cell lung cancer patients
Trédaniel, J, Becht, C, Bekradda, M, De Cremoux, H, Alexandre, J, Chomy, F, Szyldergemajn, S, Yataghene, Y, Culine, S
Published in Lung cancer (Amsterdam, Netherlands) (01.02.2009)
Published in Lung cancer (Amsterdam, Netherlands) (01.02.2009)
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Prognostic factors for survival in patients with brain metastases from renal cell carcinoma
Culine, Stéphane, Bekradda, Mohamed, Kramar, Andrew, Rey, Annie, Escudier, Bernard, Droz, Jean‐Pierre
Published in Cancer (15.12.1998)
Published in Cancer (15.12.1998)
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Randomized Multicenter Phase II Study Comparing a Combination of Fluorouracil and Folinic Acid and Alternating Irinotecan and Oxaliplatin With Oxaliplatin and Irinotecan in Fluorouracil-Pretreated Metastatic Colorectal Cancer Patients
BECOUARN, Yves, GAMELIN, Erick, BEKRADDA, Mohamed, MIGNARD, Dominique, MOUSSEAU, Mireille, COUDERT, Bruno, NEGRIER, Sylvie, PIERGA, Jean-Yves, RAOUL, Jean-Luc, PROVENCAL, Jocelyne, RIXE, Olivier, KRISCH, Claude, GERMA, Caroline
Published in Journal of clinical oncology (15.11.2001)
Published in Journal of clinical oncology (15.11.2001)
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Phase I and pharmacological study of an oxaliplatin and carboplatin combination in advanced malignancies
Mita, C., Chatelut, E., Bekradda, M., Soulié, P., Canal, P., Misset, J.-L., Cvitkovic, E., Bugat, R.
Published in Annals of oncology (01.12.2003)
Published in Annals of oncology (01.12.2003)
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Oxaliplatin plus vinorelbine in advanced non-small-cell lung cancer: final results of a multicenter phase II study
MONNET, I, DE CREMOUX, H, CVITKOVIC, E, SOULIE, P, SALTIEL-VOISIN, S, BEKRADDA, M, SALTIEL, J.-C, BRAIN, E, RIXE, O, YATAGHENE, Y, MISSET, J.-L
Published in Annals of oncology (2002)
Published in Annals of oncology (2002)
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943. Prognostic Determinants Associated with Efficacy of Adenoviral p53 Gene Therapy in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck
Nemunaitis, John, Bier-Laning, Carol, Clayman, Gary L., Van Echo, David, Guertin, L., Hamm, J., Dreicer, Robert, Yoo, George H., Minn, H., Bekradda, M., Sutherland, W., Menander, Kerstin B., Sobol, Robert E., Goodwin, Jerry
Published in Molecular therapy (01.05.2006)
Published in Molecular therapy (01.05.2006)
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New possibilities in chemotherapy for colorectal cancer
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Cisplatin and ifosfamide with either vinblastine or etoposide as salvage therapy for refractory or relapsing germ cell tumor patients: The Institut Gustave Roussy experience
Farhat, Fadi, Culine, Stéphane, Théodore, Christine, Békradda, Mohamed, Terrier‐Lacombe, Marie‐Josée, Droz, Jean‐Pierre
Published in Cancer (15.03.1996)
Published in Cancer (15.03.1996)
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Phase I/II Study of Escalating Doses of Vinorelbine in Combination With Oxaliplatin in Patients With Advanced Non–Small-Cell Lung Cancer
MONNET, Isobelle, SOULIE, Patrick, DE CREMOUX, Hubert, SALTIEL-VOISIN, Sabine, BEKRADDA, Mohammed, SALTIEL, Jean-Claude, BRAIN, Etienne, DUPONT-ANDRE, Ghislaine, CVITKOVIC, Esteban
Published in Journal of clinical oncology (15.01.2001)
Published in Journal of clinical oncology (15.01.2001)
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Antitumoral activity of oxaliplatin/cisplatin-based combination therapy in cisplatin-refractory germ cell cancer patients
SOULIE, P, GARRINO, C, BENSMAÏNE, M. A, BEKRADDA, M, BRAIN, E, DI PALMA, M, GOUPIL, A, MISSET, J. L, CVITKOVIC, E
Published in Journal of cancer research and clinical oncology (01.12.1999)
Published in Journal of cancer research and clinical oncology (01.12.1999)
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