Phase I Study of Sequence-Selective Minor Groove DNA Binding Agent SJG-136 in Patients with Advanced Solid Tumors
HOCHHAUSER, Daniel, MEYER, Timothy, JODRELL, Duncan, SPANSWICK, VictoriaJ, WU, Jenny, CLINGEN, Peter H, LOADMAN, Paul, COBB, Margaret, GUMBRELL, Lindsey, BEGENT, Richard H, HARTLEY, John A
Published in Clinical cancer research (15.03.2009)
Published in Clinical cancer research (15.03.2009)
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Production of recombinant protein in Pichia pastoris by fermentation
Tolner, Berend, Smith, Lisa, Begent, Richard H J, Chester, Kerry A
Published in Nature protocols (01.08.2006)
Published in Nature protocols (01.08.2006)
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Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy
SHARMA, Surinder K, PEDLEY, R. Barbara, BEGENT, Richard H. J, CHESTER, Kerry A, BHATIA, Jeetendra, BOXER, Geoffrey M, EL-EMIR, Ethaar, QURESHI, Uzma, TOLNER, Berend, LOWE, Helen, MICHAEL, N. Paul, MINTON, Nigel
Published in Clinical cancer research (15.01.2005)
Published in Clinical cancer research (15.01.2005)
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A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol Mustard Prodrug
Mayer, Astrid, Francis, Roslyn J, Sharma, Surinder K, Tolner, Berend, Springer, Caroline J, Martin, Jan, Boxer, Geoff M, Bell, James, Green, Alan J, Hartley, John A, Cruickshank, Clare, Wren, Julie, Chester, Kerry A, Begent, Richard H J
Published in Clinical cancer research (01.11.2006)
Published in Clinical cancer research (01.11.2006)
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Localization of radiolabeled anti-CEA antibody in subcutaneous and intrahepatic colorectal xenografts: influence of tumor size and location within host organ on antibody uptake
Dearling, Jason L.J, Flynn, Aiden A, Qureshi, Uzma, Whiting, Stephen, Boxer, Geoffrey M, Green, Alan, Begent, Richard H.J, Pedley, R. Barbara
Published in Nuclear medicine and biology (01.11.2009)
Published in Nuclear medicine and biology (01.11.2009)
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A Phase I Trial of Radioimmunotherapy with 131I-A5B7 Anti-CEA Antibody in Combination with Combretastatin-A4-Phosphate in Advanced Gastrointestinal Carcinomas
MEYER, Tim, GAYA, Andrew M, FOLKES, Lisa K, CHAN, Pei-San, BARBARA PEDLEY, R, CHESTER, Kerry A, OWEN, Karen, VIOLET, John A, MALARODA, Alessandra, GREEN, Alan J, BUSCOMBE, John, PADHANI, Anwar R, DANCEY, Gairin, RUSTIN, Gordon J, BEGENT, Richard H, STRATFORD, Michael R. L, OTHMAN, Shokri, SHARMA, Surinder K, WELLSTED, David, TAYLOR, N. Jane, STIRLING, J. James, POUPARD, Linda
Published in Clinical cancer research (01.07.2009)
Published in Clinical cancer research (01.07.2009)
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The nonuniformity of antibody distribution in the kidney and its influence on dosimetry
Flynn, Aiden A, Pedley, R Barbara, Green, Alan J, Dearling, Jason L, El-Emir, Ethaar, Boxer, Geoffrey M, Boden, Robert, Begent, Richard H J
Published in Radiation research (01.02.2003)
Published in Radiation research (01.02.2003)
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Nanoparticles functionalised with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells
Vigor, Kim L, Kyrtatos, Panagiotis G, Minogue, Shane, Al-Jamal, Khuloud T, Kogelberg, Heide, Tolner, Berend, Kostarelos, Kostas, Begent, Richard H, Pankhurst, Quentin A, Lythgoe, Mark F, Chester, Kerry A
Published in Biomaterials (01.02.2010)
Published in Biomaterials (01.02.2010)
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A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics
Spencer, Daniel I. R., Robson, Lynda, Purdy, Des, Whitelegg, Nick R., Michael, N. Paul, Bhatia, Jeetendra, Sharma, Surinder K., Rees, Anthony R., Minton, Nigel P., Begent, Richard H. J., Chester, Kerry A.
Published in Proteomics (Weinheim) (01.03.2002)
Published in Proteomics (Weinheim) (01.03.2002)
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A model‐based approach for the optimization of radioimmunotherapy through antibody design and radionuclide selection
Flynn, Aiden A., Green, Alan J., Pedley, R. Barbara, Boxer, Geoffrey M., Dearling, Jason, Watson, Rebecca, Boden, Robert, Begent, Richard H. J.
Published in Cancer (15.02.2002)
Published in Cancer (15.02.2002)
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Conference Proceeding
Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus
Kogelberg, Heide, Tolner, Berend, Thomas, Gareth J, Di Cara, Danielle, Minogue, Shane, Ramesh, Bala, Sodha, Serena, Marsh, Dan, Lowdell, Mark W, Meyer, Tim, Begent, Richard H J, Hart, Ian, Marshall, John F, Chester, Kerry
Published in Journal of molecular biology (03.10.2008)
Published in Journal of molecular biology (03.10.2008)
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Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy
Kogelberg, Heide, Tolner, Berend, Sharma, Surinder K, Lowdell, Mark W, Qureshi, Uzma, Robson, Mathew, Hillyer, Tim, Pedley, R. Barbara, Vervecken, Wouter, Contreras, Roland, Begent, Richard H.J, Chester, Kerry A
Published in Glycobiology (Oxford) (01.01.2007)
Published in Glycobiology (Oxford) (01.01.2007)
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Microdistribution of Targeted, Fluorescently Labeled Anti–Carcinoembryonic Antigen Antibody in Metastatic Colorectal Cancer: Implications for Radioimmunotherapy
Fidarova, Elena F., El-Emir, Ethaar, Boxer, Geoffrey M., Qureshi, Uzma, Dearling, Jason L.J., Robson, Mathew P., Begent, Richard H.J., Trott, Klaus R., Pedley, R. Barbara
Published in Clinical cancer research (01.05.2008)
Published in Clinical cancer research (01.05.2008)
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IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA
Klöhn, Peter-Christian, Wuellner, Ulrich, Zizlsperger, Nora, Zhou, Yu, Tavares, Daniel, Berger, Sven, Zettlitz, Kirstin A, Proetzel, Gabriele, Yong, May, Begent, Richard H J, Reichert, Janice M
Published in mAbs (01.03.2013)
Published in mAbs (01.03.2013)
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Expanded-bed adsorption immobilized-metal affinity chromatography
Tolner, Berend, Smith, Lisa, Begent, Richard H J, Chester, Kerry A
Published in Nature protocols (01.09.2006)
Published in Nature protocols (01.09.2006)
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Incentivizing standards development and adoption
Reddington, Fiona, Wilkinson, J Max, Clark, Robin, Begent, Richard H
Published in Nature biotechnology (01.04.2007)
Published in Nature biotechnology (01.04.2007)
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Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice
El-Emir, Ethaar, Boxer, Geoffrey M., Petrie, Ingrid A., Boden, Robert W., Dearling, Jason L.J., Begent, Richard H.J., Pedley, R. Barbara
Published in European journal of cancer (1990) (01.03.2005)
Published in European journal of cancer (1990) (01.03.2005)
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