Protective and Toxic Neuroinflammation in Amyotrophic Lateral Sclerosis
Hooten, Kristopher G., Beers, David R., Zhao, Weihua, Appel, Stanley H.
Published in Neurotherapeutics (01.04.2015)
Published in Neurotherapeutics (01.04.2015)
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Journal Article
Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
Liao, Bing, Zhao, Weihua, Beers, David R., Henkel, Jenny S., Appel, Stanley H.
Published in Experimental neurology (01.09.2012)
Published in Experimental neurology (01.09.2012)
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Journal Article
Immune-mediated Mechanisms in the Pathoprogression of Amyotrophic Lateral Sclerosis
Zhao, Weihua, Beers, David R., Appel, Stanley H.
Published in Journal of neuroimmune pharmacology (01.09.2013)
Published in Journal of neuroimmune pharmacology (01.09.2013)
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Journal Article
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
Beers, David R, Henkel, Jenny S, Zhao, Weihua, Wang, Jinghong, Appel, Stanley H
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2008)
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Journal Article
Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes
Zhao, Weihua, Beers, David R, Hooten, Kristopher G, Sieglaff, Douglas H, Zhang, Aijun, Kalyana-Sundaram, Shanker, Traini, Christopher M, Halsey, Wendy S, Hughes, Ashley M, Sathe, Ganesh M, Livi, George P, Fan, Guo-Huang, Appel, Stanley H
Published in JAMA neurology (01.06.2017)
Published in JAMA neurology (01.06.2017)
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Journal Article
Wild-Type Microglia Extend Survival in PU.1 Knockout Mice with Familial Amyotrophic Lateral Sclerosis
Beers, David R., Henkel, Jenny S., Xiao, Qin, Zhao, Weihua, Wang, Jinghong, Yen, Albert A., Siklos, Laszlo, McKercher, Scott R., Appel, Stanley H.
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2006)
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Journal Article
Extracellular mutant SOD1 induces microglial-mediated motoneuron injury
Zhao, Weihua, Beers, David R., Henkel, Jenny S., Zhang, Wei, Urushitani, Makoto, Julien, Jean-Pierre, Appel, Stanley H.
Published in Glia (15.01.2010)
Published in Glia (15.01.2010)
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Journal Article
Microglia in ALS: The Good, The Bad, and The Resting
Henkel, Jenny S., Beers, David R., Zhao, Weihua, Appel, Stanley H.
Published in Journal of neuroimmune pharmacology (01.12.2009)
Published in Journal of neuroimmune pharmacology (01.12.2009)
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Journal Article
Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice
Beers, David R, Zhao, Weihua, Liao, Bing, Kano, Osamu, Wang, Jinghong, Huang, Ailing, Appel, Stanley H, Henkel, Jenny S
Published in Brain, behavior, and immunity (01.07.2011)
Published in Brain, behavior, and immunity (01.07.2011)
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Journal Article
Functional alterations of myeloid cells during the course of Alzheimer's disease
Thome, Aaron D, Faridar, Alireza, Beers, David R, Thonhoff, Jason R, Zhao, Weihua, Wen, Shixiang, Pascual, Belen, Masdeu, Joseph C, Appel, Stanley H
Published in Molecular neurodegeneration (13.11.2018)
Published in Molecular neurodegeneration (13.11.2018)
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Journal Article
Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation
Thome, Aaron D., Thonhoff, Jason R., Zhao, Weihua, Faridar, Alireza, Wang, Jinghong, Beers, David R., Appel, Stanley H.
Published in Frontiers in immunology (22.06.2022)
Published in Frontiers in immunology (22.06.2022)
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A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis
Thonhoff, Jason R, Beers, David R, Zhao, Weihua, Faridar, Alireza, Thome, Aaron, Wen, Shixiang, Zhang, Aijun, Wang, Jinghong, Appel, Stanley H
Published in Frontiers in neurology (10.06.2024)
Published in Frontiers in neurology (10.06.2024)
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Journal Article
Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease
Faridar, Alireza, Vasquez, Matthew, Thome, Aaron D, Yin, Zheng, Xuan, Hui, Wang, Jing Hong, Wen, Shixiang, Li, Xuping, Thonhoff, Jason R, Zhao, Weihua, Zhao, Hong, Beers, David R, Wong, Stephen T C, Masdeu, Joseph C, Appel, Stanley H
Published in Acta neuropathologica communications (30.09.2022)
Published in Acta neuropathologica communications (30.09.2022)
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Journal Article
Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease
Thome, Aaron D., Atassi, Farah, Wang, Jinghong, Faridar, Alireza, Zhao, Weihua, Thonhoff, Jason R., Beers, David R., Lai, Eugene C., Appel, Stanley H.
Published in NPJ Parkinson's Disease (13.05.2021)
Published in NPJ Parkinson's Disease (13.05.2021)
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Journal Article
Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis
Vaknin, Ilan, Kunis, Gilad, Miller, Omer, Butovsky, Oleg, Bukshpan, Shay, Beers, David R, Henkel, Jenny S, Yoles, Eti, Appel, Stanley H, Schwartz, Michal
Published in PloS one (03.11.2011)
Published in PloS one (03.11.2011)
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Journal Article
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
Henkel, Jenny S., Engelhardt, Joseph I., Siklós, László, Simpson, Ericka P., Kim, Seung H., Pan, Tianhong, Goodman, J. Clay, Siddique, Teepu, Beers, David R., Appel, Stanley H.
Published in Annals of neurology (01.02.2004)
Published in Annals of neurology (01.02.2004)
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