A Selective Prostaglandin E2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques
Fox, Brian M, Beck, Hilary P, Roveto, Philip M, Kayser, Frank, Cheng, Qingwen, Dou, Hannah, Williamson, Toni, Treanor, James, Liu, Hantao, Jin, Lixia, Xu, Guifen, Ma, Ji, Wang, Songli, Olson, Steven H
Published in Journal of medicinal chemistry (09.07.2015)
Published in Journal of medicinal chemistry (09.07.2015)
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Journal Article
Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction
Rew, Yosup, Sun, Daqing, Gonzalez-Lopez De Turiso, Felix, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Deignan, Jeffrey, Fox, Brian M, Gustin, Darin, Huang, Xin, Jiang, Min, Jiao, Xianyun, Jin, Lixia, Kayser, Frank, Kopecky, David J, Li, Yihong, Lo, Mei-Chu, Long, Alexander M, Michelsen, Klaus, Oliner, Jonathan D, Osgood, Tao, Ragains, Mark, Saiki, Anne Y, Schneider, Steve, Toteva, Maria, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Journal Article
Optimized Properties and Synthesis of Photoactivatable Diazoketorhodamines Facilitate and Enhance High-Throughput Single-Molecule Tracking
Pino, Nicholas W., Sizemore, Anne R., Cleary, Leah, Liu, Helen, McSwiggen, David T., Song, Dan, Beck, Hilary P., Cheng, Kylie, Hardy, Miki, Hsiung, Jessica, Tang, Yangzhong, Anugula, Rajender, Lakshman, Santhosh, Merneedi, Ravi K., Sinha, Pradipta
Published in Journal of organic chemistry (18.10.2024)
Published in Journal of organic chemistry (18.10.2024)
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Journal Article
Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development
Sun, Daqing, Li, Zhihong, Rew, Yosup, Gribble, Michael, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chen, Xiaoqi, Chow, David, Deignan, Jeffrey, Duquette, Jason, Eksterowicz, John, Fisher, Benjamin, Fox, Brian M, Fu, Jiasheng, Gonzalez, Ana Z, Gonzalez-Lopez De Turiso, Felix, Houze, Jonathan B, Huang, Xin, Jiang, Min, Jin, Lixia, Kayser, Frank, Liu, Jiwen (Jim), Lo, Mei-Chu, Long, Alexander M, Lucas, Brian, McGee, Lawrence R, McIntosh, Joel, Mihalic, Jeff, Oliner, Jonathan D, Osgood, Tao, Peterson, Matthew L, Roveto, Philip, Saiki, Anne Y, Shaffer, Paul, Toteva, Maria, Wang, Yingcai, Wang, Yu Chung, Wortman, Sarah, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Yu, Ming, Zhao, Xiaoning, Zhou, Jing, Zhu, Jiang, Olson, Steven H, Medina, Julio C
Published in Journal of medicinal chemistry (27.02.2014)
Published in Journal of medicinal chemistry (27.02.2014)
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Journal Article
Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T-reg Trafficking into the Tumor Microenvironment
Jackson, Jeffrey J., Ketcham, John M., Younai, Ashkaan, Abraham, Betty, Biannic, Berenger, Beck, Hilary P., Bui, Minna H. T., Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X., Jacobson, Scott, Karbarz, Emily, Kassner, Paul D., Marshall, Lisa, McKinnell, Jenny, Meleza, Cesar, Okal, Abood, Pookot, Deepa, Reilly, Maureen K., Robles, Omar, Shunatona, Hunter P., Talay, Oezcan, Walker, James R., Wadsworth, Angela, Wustrow, David J., Zibinsky, Mikhail
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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Journal Article
Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment
Jackson, Jeffrey J, Ketcham, John M, Younai, Ashkaan, Abraham, Betty, Biannic, Berenger, Beck, Hilary P, Bui, Minna H. T, Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X, Jacobson, Scott, Karbarz, Emily, Kassner, Paul D, Marshall, Lisa, McKinnell, Jenny, Meleza, Cesar, Okal, Abood, Pookot, Deepa, Reilly, Maureen K, Robles, Omar, Shunatona, Hunter P, Talay, Oezcan, Walker, James R, Wadsworth, Angela, Wustrow, David J, Zibinsky, Mikhail
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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Journal Article
Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction
Gonzalez, Ana Z, Eksterowicz, John, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Duquette, Jason, Fox, Brian M, Fu, Jiasheng, Huang, Xin, Houze, Jonathan B, Jin, Lixia, Li, Yihong, Li, Zhihong, Ling, Yun, Lo, Mei-Chu, Long, Alexander M, McGee, Lawrence R, McIntosh, Joel, McMinn, Dustin L, Oliner, Jonathan D, Osgood, Tao, Rew, Yosup, Saiki, Anne Y, Shaffer, Paul, Wortman, Sarah, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Olson, Steven H, Medina, Julio C, Sun, Daqing
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors
Gonzalez-Lopez de Turiso, Felix, Sun, Daqing, Rew, Yosup, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Correll, Tiffany L, Huang, Xin, Julian, Lisa D, Kayser, Frank, Lo, Mei-Chu, Long, Alexander M, McMinn, Dustin, Oliner, Jonathan D, Osgood, Tao, Powers, Jay P, Saiki, Anne Y, Schneider, Steve, Shaffer, Paul, Xiao, Shou-Hua, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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Journal Article
Discovery of AM-7209, a Potent and Selective 4‑Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction
Rew, Yosup, Sun, Daqing, Yan, Xuelei, Beck, Hilary P, Canon, Jude, Chen, Ada, Duquette, Jason, Eksterowicz, John, Fox, Brian M, Fu, Jiasheng, Gonzalez, Ana Z, Houze, Jonathan, Huang, Xin, Jiang, Min, Jin, Lixia, Li, Yihong, Li, Zhihong, Ling, Yun, Lo, Mei-Chu, Long, Alexander M, McGee, Lawrence R, McIntosh, Joel, Oliner, Jonathan D, Osgood, Tao, Saiki, Anne Y, Shaffer, Paul, Wang, Yu Chung, Wortman, Sarah, Yakowec, Peter, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H
Published in Journal of medicinal chemistry (26.12.2014)
Published in Journal of medicinal chemistry (26.12.2014)
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Journal Article
Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres
Gonzalez, Ana Z, Li, Zhihong, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Duquette, Jason, Eksterowicz, John, Fox, Brian M, Fu, Jiasheng, Huang, Xin, Houze, Jonathan, Jin, Lixia, Li, Yihong, Ling, Yun, Lo, Mei-Chu, Long, Alexander M, McGee, Lawrence R, McIntosh, Joel, Oliner, Jonathan D, Osgood, Tao, Rew, Yosup, Saiki, Anne Y, Shaffer, Paul, Wortman, Sarah, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Olson, Steven H, Sun, Daqing, Medina, Julio C
Published in Journal of medicinal chemistry (10.04.2014)
Published in Journal of medicinal chemistry (10.04.2014)
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Journal Article
Improvement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitors
Beck, Hilary P., DeGraffenreid, Michael, Fox, Brian, Allen, John G., Rew, Yosup, Schneider, Stephen, Saiki, Anne Y., Yu, Dongyin, Oliner, Jonathan D., Salyers, Kevin, Ye, Qiuping, Olson, Steven
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
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Journal Article
Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents
BECK, Hilary P, KOHN, Todd, FRANK, Brendon, AN, Songhzu, WICKRAMASINGHE, Dineli, JAEN, Juan, MEDINA, Julio, HUNGATE, Randall, WANG SHEN, RUBENSTEIN, Steven, HEDBERG, Christine, SCHWANDNER, Ralf, HASSLINGER, Kerstin, KANG DAI, CONG LI, LINGMING LIANG, WESCHE, Holger
Published in Bioorganic & medicinal chemistry letters (01.02.2008)
Published in Bioorganic & medicinal chemistry letters (01.02.2008)
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Journal Article
A Selective Prostaglandin E-2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques
Fox, Brian M., Beck, Hilary P., Roveto, Philip M., Kayser, Frank, Cheng, Qingwen, Dou, Hannah, Williamson, Toni, Treanor, James, Liu, Hantao, Jin, Lixia, Xu, Guifen, Ma, Ji, Wang, Songli, Olson, Steven H.
Published in Journal of medicinal chemistry (09.07.2015)
Published in Journal of medicinal chemistry (09.07.2015)
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Journal Article
Abstract 4290: Potent and selective next generation inhibitors of indoleamine-2,3-dioxygenase (IDO1) for the treatment of cancer
Powers, Jay P., Walters, Matthew J., Noubade, Rajkumar, Young, Stephen W., Marshall, Lisa, Melom, Jan, Park, Adam, Shah, Nick, Bjork, Pia, Fridman, Jordan S., Beck, Hilary P., Chian, David, McKinnell, Jenny V., Osipov, Maksim, Reilly, Maureen K., Shunatona, Hunter P., Walker, James R., Zibinsky, Mikhail, Jaen, Juan C.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Discovery of potent LPA sub(2) (EDG4) antagonists as potential anticancer agents
Beck, Hilary P, Kohn, Todd, Rubenstein, Steven, Hedberg, Christine, Schwandner, Ralf, Hasslinger, Kerstin, Dai, Kang, Li, Cong, Liang, Lingming, Wesche, Holger, Frank, Brendon, An, Songhzu, Wickramasinghe, Dineli, Jaen, Juan, Medina, Julio, Hungate, Randall, Shen, Wang
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Journal Article
Discovery of potent LPA 2 (EDG4) antagonists as potential anticancer agents
Beck, Hilary P., Kohn, Todd, Rubenstein, Steven, Hedberg, Christine, Schwandner, Ralf, Hasslinger, Kerstin, Dai, Kang, Li, Cong, Liang, Lingming, Wesche, Holger, Frank, Brendon, An, Songhzu, Wickramasinghe, Dineli, Jaen, Juan, Medina, Julio, Hungate, Randall, Shen, Wang
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
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Journal Article
AhR MODULATORS
BECK HILARY P, ALAM MUZAFFAR, SUTTON JAMES CLIFFORD JR, DILLON MICHAEL P, GONZALEZ-LOPEZ MARCOS
Year of Publication 18.09.2020
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Year of Publication 18.09.2020
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