Metastin (KiSS-1) Mimetics Identified from Peptide Structure−Activity Relationship-Derived Pharmacophores and Directed Small Molecule Database Screening
Orsini, Michael J, Klein, Mark A, Beavers, Mary Pat, Connolly, Peter J, Middleton, Steven A, Mayo, Kevin H
Published in Journal of medicinal chemistry (08.02.2007)
Published in Journal of medicinal chemistry (08.02.2007)
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Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: The confounding effects of DTT and cysteine in biological assays
Myers, Michael C., Napper, Andrew D., Motlekar, Nuzhat, Shah, Parag P., Chiu, Chun-Hao, Beavers, Mary Pat, Diamond, Scott L., Huryn, Donna M., Smith, Amos B.
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
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Journal Article
Antibody modeling assessment
Almagro, Juan C., Beavers, Mary Pat, Hernandez-Guzman, Francisco, Maier, Johannes, Shaulsky, Jodi, Butenhof, Kenneth, Labute, Paul, Thorsteinson, Nels, Kelly, Kenneth, Teplyakov, Alexey, Luo, Jinquan, Sweet, Raymond, Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.11.2011)
Published in Proteins, structure, function, and bioinformatics (01.11.2011)
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Journal Article
Design, synthesis and biological evaluation of a library of thiocarbazates and their activity as cysteine protease inhibitors
Liu, Zhuqing, Myers, Michael C, Shah, Parag P, Beavers, Mary Pat, Benedetti, Phillip A, Diamond, Scott L, Smith, 3rd, Amos B, Huryn, Donna M
Published in Combinatorial chemistry & high throughput screening (01.05.2010)
Published in Combinatorial chemistry & high throughput screening (01.05.2010)
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Small-molecule inhibitors of integrin α₂β₁ that prevent pathological thrombus formation via an allosteric mechanism
Miller, Meredith W, Basra, Sandeep, Kulp, Daniel W, Billings, Paul C, Choi, Sungwook, Beavers, Mary Pat, McCarty, Owen J.T, Zou, Zhiying, Kahn, Mark L, Bennett, Joel S, DeGrado, William F
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
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Journal Article
The Total Synthesis of Roquefortine C and a Rationale for the Thermodynamic Stability of Isoroquefortine C over Roquefortine C
Shangguan, Ning, Hehre, Warren J, Ohlinger, William S, Beavers, Mary Pat, Joullié, Madeleine M
Published in Journal of the American Chemical Society (14.05.2008)
Published in Journal of the American Chemical Society (14.05.2008)
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Journal Article
Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L
Shah, Parag P, Myers, Michael C, Beavers, Mary Pat, Purvis, Jeremy E, Jing, Huiyan, Grieser, Heather J, Sharlow, Elizabeth R, Napper, Andrew D, Huryn, Donna M, Cooperman, Barry S, Smith, 3rd, Amos B, Diamond, Scott L
Published in Molecular pharmacology (01.07.2008)
Published in Molecular pharmacology (01.07.2008)
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Journal Article
Heteroaryl- O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1
Zhang, Xiaoyan, Urbanski, Maud, Patel, Mona, Zeck, Roxanne E., Cox, Geoffrey G., Bian, Haiyan, Conway, Bruce R., Pat Beavers, Mary, Rybczynski, Philip J., Demarest, Keith T.
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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Journal Article
The Nociceptin Pharmacophore Site for Opioid Receptor Binding Derived from the NMR Structure and Bioactivity Relationships
Orsini, Michael J, Nesmelova, Irina, Young, Helen C, Hargittai, Balazs, Beavers, Mary Pat, Liu, Jingchun, Connolly, Peter J, Middleton, Steven A, Mayo, Kevin H
Published in The Journal of biological chemistry (04.03.2005)
Published in The Journal of biological chemistry (04.03.2005)
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Journal Article
Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors
Dudash, Joseph, Zhang, Yongzheng, Moore, John B., Look, Richard, Liang, Yin, Beavers, Mary Pat, Conway, Bruce R., Rybczynski, Philip J., Demarest, Keith T.
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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Journal Article
Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain
Beavers, Mary Pat, Myers, Michael C, Shah, Parag P, Purvis, Jeremy E, Diamond, Scott L, Cooperman, Barry S, Huryn, Donna M, Smith, Amos B
Published in Journal of Chemical Information and Modeling (01.07.2008)
Published in Journal of Chemical Information and Modeling (01.07.2008)
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Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors
Kuo, Gee-Hong, Prouty, Catherine, DeAngelis, Alan, Shen, Lan, O'Neill, David J, Shah, Chandra, Connolly, Peter J, Murray, William V, Conway, Bruce R, Cheung, Peter, Westover, Lori, Xu, Jun Z, Look, Richard A, Demarest, Keith T, Emanuel, Stuart, Middleton, Steven A, Jolliffe, Linda, Beavers, Mary Pat, Chen, Xin
Published in Journal of medicinal chemistry (11.09.2003)
Published in Journal of medicinal chemistry (11.09.2003)
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Journal Article
Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype
Myers, Michael C., Shah, Parag P., Beavers, Mary Pat, Napper, Andrew D., Diamond, Scott L., Smith, Amos B., Huryn, Donna M.
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Journal Article
Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain
Beavers, Mary Pat, Myers, Michael C, Shah, Parag P, Purvis, Jeremy E, Diamond, Scott L, Cooperman, Barry S, Huryn, Donna M, Smith, Amos B
Published in Journal of chemical information and modeling (27.12.2010)
Published in Journal of chemical information and modeling (27.12.2010)
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Journal Article
Small-molecule inhibitors of integrin α 2 β 1 that prevent pathological thrombus formation via an allosteric mechanism
Miller, Meredith W., Basra, Sandeep, Kulp, Daniel W., Billings, Paul C., Choi, Sungwook, Beavers, Mary Pat, McCarty, Owen J. T., Zou, Zhiying, Kahn, Mark L., Bennett, Joel S., DeGrado, William F.
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
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Journal Article
Small-molecule inhibitors of integrin [alpha]^sub 2^[beta]^sub 1^ that prevent pathological thrombus formation via an allosteric mechanism
Miller, Meredith W, Basra, Sandeep, Kulp, Daniel W, Billings, Paul C, Choi, Sungwook, Beavers, Mary Pat, McCarty, Owen J T, Zou, Zhiying, Kahn, Mark L, Bennett, Joel S, DeGrado, William F
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
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Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
Journal Article
Nonpeptidic, Noncovalent Inhibitors of the Cysteine Protease Cathepsin S
Thurmond, Robin L, Beavers, Mary Pat, Cai, Hui, Meduna, Steven P, Gustin, Darin J, Sun, Siquan, Almond, Harold J, Karlsson, Lars, Edwards, James P
Published in Journal of medicinal chemistry (23.09.2004)
Published in Journal of medicinal chemistry (23.09.2004)
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Journal Article
Small-molecule inhibitors of integrin αâβâ that prevent pathological thrombus formation via an allosteric mechanism
Miller, Meredith W, Basra, Sandeep, Kulp, Daniel W, Billings, Paul C, Choi, Sungwook, Beavers, Mary Pat, McCarty, Owen J.T, Zou, Zhiying, Kahn, Mark L, Bennett, Joel S, DeGrado, William F
Published in Proceedings of the National Academy of Sciences - PNAS (2009)
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Published in Proceedings of the National Academy of Sciences - PNAS (2009)
Journal Article
Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2
Zhang, Xiaoyan, Urbanski, Maud, Patel, Mona, Cox, Geoffrey G., Zeck, Roxanne E., Bian, Haiyan, Conway, Bruce R., Beavers, Mary Pat, Rybczynski, Philip J., Demarest, Keith T.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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