Sugar substitutes: their energy values, bulk characteristics, and potential health benefits
Levin, GV, Zehner, LR, Saunders, JP, Beadle, JR
Published in The American journal of clinical nutrition (01.11.1995)
Published in The American journal of clinical nutrition (01.11.1995)
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Conference Proceeding
Alkylthioglycerol Prodrugs of Foscarnet: Synthesis, Oral Bioavailability and Structure–Activity Studies in Human Cytomegalovirus-, Herpes Simplex Virus Type 1- and Human Immunodeficiency Virus Type 1-Infected Cells
Beadle, JR, Kini, GD, Aldern, KA, Gardner, MF, Wright, KN, Richman, DD, Hostetler, KY
Published in Antiviral chemistry & chemotherapy (01.01.1998)
Published in Antiviral chemistry & chemotherapy (01.01.1998)
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Intravitreal Toxicology and Duration of Efficacy of a Novel Antiviral Lipid Prodrug of Ganciclovir in Liposome Formulation
Cheng, Lingyun, Hostetler, Karl Y, Chaidhawangul, Sunan, Gardner, Michael F, Beadle, James R, Keefe, Kelly S, Bergeron-Lynn, Germaine, Severson, Gregory M, Soules, Kelly A, Mueller, Arthur J, Freeman, William R
Published in Investigative ophthalmology & visual science (01.05.2000)
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Published in Investigative ophthalmology & visual science (01.05.2000)
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Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection
HOSTETLER, K. Y, BEADLE, J. R, HORNBUCKLE, W. E, BELLEZZA, C. A, TOCHKOV, I. A, COTE, P. J, GERIN, J. L, KORBA, B. E, TENNANT, B. C
Published in Antimicrobial Agents and Chemotherapy (01.07.2000)
Published in Antimicrobial Agents and Chemotherapy (01.07.2000)
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Enhanced oral absorption and antiviral activity of 1- O-octadecyl- sn-glycero-3-phospho-acyclovir and related compounds in hepatitis b virus infection, in vitro
Hostetler, Karl Y., Beadle, James R., Kini, Ganesh D., Gardner, Michael F., Wright, Kristine N., Wu, Tong-Hau, Korba, Brent A.
Published in Biochemical pharmacology (15.06.1997)
Published in Biochemical pharmacology (15.06.1997)
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In vitro and in vivo activity of 1-O-hexadecylpropanediol-3-phospho-ganciclovir and 1-O-hexadecylpropanediol-3-phospho-penciclovir in cytomegalovirus and herpes simplex virus infections
Hostetler, K Y, Rybak, R J, Beadle, J R, Gardner, M F, Aldern, K A, Wright, K N, Kern, E R
Published in Antiviral chemistry & chemotherapy (01.01.2001)
Published in Antiviral chemistry & chemotherapy (01.01.2001)
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Alkoxy propane prodrugs of foscarnet: effect of alkyl chain length on in vitro antiviral activity in cells infected with HIV-1, HSV-1 and HCMV
Kini, Ganesh D, Beadle, James R, Xie, Hong, Aldern, Kathy A, Richman, Douglas D, Y. Hostetler, Karl
Published in Antiviral research (01.09.1997)
Published in Antiviral research (01.09.1997)
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Enhanced Inhibition of Orthopoxvirus Replication In Vitro by Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir
KERN, Earl R, HARTLINE, Caroll, HARDEN, Emma, KEITH, Kathy, RODRIGUEZ, Natalie, BEADLE, James R, HOSTETLER, Karl Y
Published in Antimicrobial Agents and Chemotherapy (01.04.2002)
Published in Antimicrobial Agents and Chemotherapy (01.04.2002)
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In vitro Anti-HIV-1 Activity of sn-2-Substituted 1-O-Octadecyl-sn-Glycero-3-Phosphonoformate Analogues and Synergy with Zidovudine
Hostetler, Karl Y, Hammond, Jennifer L, Kini, Ganesh D, Hostetler, Saskia E, Beadle, James R, Aldern, Kathy A, Chou, Ting-Chao, Richman, Douglas D, Mellors, John W
Published in Antiviral chemistry & chemotherapy (01.05.2000)
Published in Antiviral chemistry & chemotherapy (01.05.2000)
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Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model
Buller, R.Mark, Owens, Gelita, Schriewer, Jill, Melman, Lora, Beadle, James R, Hostetler, Karl Y
Published in Virology (New York, N.Y.) (20.01.2004)
Published in Virology (New York, N.Y.) (20.01.2004)
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Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir Exhibit Multiple-Log Enhancement of Antiviral Activity against Cytomegalovirus and Herpesvirus Replication In Vitro
BEADLE, James R, HARTLINE, Caroll, ALDERN, Kathy A, RODRIGUEZ, Natalie, HARDEN, Emma, KERN, Earl R, HOSTETLER, Karl Y
Published in Antimicrobial Agents and Chemotherapy (01.08.2002)
Published in Antimicrobial Agents and Chemotherapy (01.08.2002)
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Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney
Ciesla, Stephanie L, Trahan, Julissa, Wan, W.Brad, Beadle, James R, Aldern, Kathy A, Painter, George R, Hostetler, Karl Y
Published in Antiviral research (01.08.2003)
Published in Antiviral research (01.08.2003)
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Ether Lipid-Ester Prodrugs of Acyclic Nucleoside Phosphonates: Activity against Adenovirus Replication In Vitro
Hartline, Caroll B., Gustin, Kortney M., Wan, William B., Ciesla, Stephanie L., Beadle, James R., Hostetler, Karl Y., Kern, Earl R
Published in The Journal of infectious diseases (01.02.2005)
Published in The Journal of infectious diseases (01.02.2005)
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Intravitreal toxicology and therapeutic efficacy of the carboxymethyl ester of the 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA-O-Me), a novel lipid antiviral prodrug for intraocular drug delivery
Cheng, L, Hostetler, K Y, Gardner, M F, Avila, Jr, C P, Bergeron-Lynn, G, Keefe, K S, Beadle, J R, Wiley, C A, Freeman, W R
Published in Journal of ocular pharmacology and therapeutics (01.08.1999)
Published in Journal of ocular pharmacology and therapeutics (01.08.1999)
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Synthesis and Antiviral Evaluation of Alkoxyalkyl Derivatives of 9-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)adenine against Cytomegalovirus and Orthopoxviruses
Beadle, James R, Wan, William B, Ciesla, Stephanie L, Keith, Kathy A, Hartline, Caroll, Kern, Earl R, Hostetler, Karl Y
Published in Journal of medicinal chemistry (23.03.2006)
Published in Journal of medicinal chemistry (23.03.2006)
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A novel cytarabine crystalline lipid prodrug: hexadecyloxypropyl cytarabine 3',5'-cyclic monophosphate for proliferative vitreoretinopathy
Kim, Jae Suk, Beadle, James R, Freeman, William R, Hostetler, Karl Y, Hartmann, Kathrin, Valiaeva, Nadejda, Kozak, Igor, Conner, Laura, Trahan, Julissa, Aldern, Kathy A, Cheng, Lingyun
Published in Molecular vision (2012)
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Published in Molecular vision (2012)
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