Pre-existing anti-factor VIII immunity alters therapeutic platelet-targeted factor VIII engraftment following busulfan conditioning through cytotoxic CD8 T cells
Jing, Weiqing, Baumgartner, Christina K., Xue, Feng, Schroeder, Jocelyn A., Shi, Qizhen
Published in Journal of thrombosis and haemostasis (01.03.2023)
Published in Journal of thrombosis and haemostasis (01.03.2023)
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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity
Baumgartner, Christina K, Ebrahimi-Nik, Hakimeh, Iracheta-Vellve, Arvin, Hamel, Keith M, Olander, Kira E, Davis, Thomas G R, McGuire, Kathleen A, Halvorsen, Geoff T, Avila, Omar I, Patel, Chirag H, Kim, Sarah Y, Kammula, Ashwin V, Muscato, Audrey J, Halliwill, Kyle, Geda, Prasanthi, Klinge, Kelly L, Xiong, Zhaoming, Duggan, Ryan, Mu, Liang, Yeary, Mitchell D, Patti, James C, Balon, Tyler M, Mathew, Rebecca, Backus, Carey, Kennedy, Domenick E, Chen, Angeline, Longenecker, Kenton, Klahn, Joseph T, Hrusch, Cara L, Krishnan, Navasona, Hutchins, Charles W, Dunning, Jax P, Bulic, Marinka, Tiwari, Payal, Colvin, Kayla J, Chuong, Cun Lan, Kohnle, Ian C, Rees, Matthew G, Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A, Wu, Meng-Ju, Suermondt, Juliette S M T, Knudsen, Nelson H, Cheruiyot, Collins K, Sen, Debattama R, Griffin, Gabriel K, Golub, Todd R, El-Bardeesy, Nabeel, Decker, Joshua H, Yang, Yi, Guffroy, Magali, Fossey, Stacey, Trusk, Patricia, Sun, Im-Meng, Liu, Yue, Qiu, Wei, Sun, Qi, Paddock, Marcia N, Farney, Elliot P, Matulenko, Mark A, Beauregard, Clay, Frost, Jennifer M, Yates, Kathleen B, Kym, Philip R, Manguso, Robert T
Published in Nature (London) (26.10.2023)
Published in Nature (London) (26.10.2023)
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Melanoma and microbiota: Current understanding and future directions
Routy, Bertrand, Jackson, Tanisha, Mählmann, Laura, Baumgartner, Christina K., Blaser, Martin, Byrd, Allyson, Corvaia, Nathalie, Couts, Kasey, Davar, Diwakar, Derosa, Lisa, Hang, Howard C., Hospers, Geke, Isaksen, Morten, Kroemer, Guido, Malard, Florent, McCoy, Kathy D., Meisel, Marlies, Pal, Sumanta, Ronai, Ze’ev, Segal, Eran, Sepich-Poore, Gregory D., Shaikh, Fyza, Sweis, Randy F., Trinchieri, Giorgio, van den Brink, Marcel, Weersma, Rinse K., Whiteson, Katrine, Zhao, Liping, McQuade, Jennifer, Zarour, Hassane, Zitvogel, Laurence
Published in Cancer cell (08.01.2024)
Published in Cancer cell (08.01.2024)
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The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity
Chen, Yingyu, Schroeder, Jocelyn A., Chen, Juan, Luo, Xiaofeng, Baumgartner, Christina K., Montgomery, Robert R., Hu, Jianda, Shi, Qizhen
Published in Blood (10.03.2016)
Published in Blood (10.03.2016)
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Peptide-MHC Class II Complex Stability Governs CD4 T Cell Clonal Selection
Baumgartner, Christina K, Ferrante, Andrea, Nagaoka, Mika, Gorski, Jack, Malherbe, Laurent P
Published in The Journal of immunology (1950) (15.01.2010)
Published in The Journal of immunology (1950) (15.01.2010)
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A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination
Baumgartner, Christina K, Yagita, Hideo, Malherbe, Laurent P
Published in The Journal of immunology (1950) (01.09.2012)
Published in The Journal of immunology (1950) (01.09.2012)
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Journal Article
Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells
Luo, Xiaofeng, Chen, Juan, Schroeder, Jocelyn A, Allen, Kenneth P, Baumgartner, Christina K, Malarkannan, Subramaniam, Hu, Jianda, Williams, Calvin B, Shi, Qizhen
Published in Frontiers in immunology (06.09.2018)
Published in Frontiers in immunology (06.09.2018)
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Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications
Patel, Shitalben, Karlsson, Marie, Klahn, Joseph T., Gambino, Frank, Costa, Helena, McGuire, Kathleen A., Baumgartner, Christina K., Williams, Jon, Sandoz, Sarah, Kath, James E.
Published in SLAS discovery (01.03.2024)
Published in SLAS discovery (01.03.2024)
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Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex
Hao, Qi, Rathinaswamy, Manoj K, Klinge, Kelly L, Bratkowski, Matthew, Mafi, Amirhossein, Baumgartner, Christina K, Hamel, Keith M, Veits, Gesine K, Jain, Rinku, Catalano, Claudio, Fitzgerald, Mark, Hird, Alexander W, Park, Eunice, Vora, Harit U, Henderson, James A, Longenecker, Kenton, Hutchins, Charles W, Qiu, Wei, Scapin, Giovanna, Sun, Qi, Stoll, Vincent S, Sun, Chaohong, Li, Ping, Eaton, Dan, Stokoe, David, Fisher, Stewart L, Nasveschuk, Christopher G, Paddock, Marcia, Kort, Michael E
Published in Communications chemistry (16.08.2024)
Published in Communications chemistry (16.08.2024)
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Journal Article
Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9
Allacher, Peter, Baumgartner, Christina K., Pordes, Aniko G., Ahmad, Rafi U., Schwarz, Hans Peter, Reipert, Birgit M.
Published in Blood (06.01.2011)
Published in Blood (06.01.2011)
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T cell–independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist
Pordes, Aniko G., Baumgartner, Christina K., Allacher, Peter, Ahmad, Rafi U., Weiller, Markus, Schiviz, Alexandra N., Schwarz, Hans Peter, Reipert, Birgit M.
Published in Blood (15.09.2011)
Published in Blood (15.09.2011)
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999 The PTPN2/N1 small molecule inhibitor ABBV-CLS-484 promotes NK cell activity driving primary tumor regression and preventing metastasis
Patel, Chirag, McGuire, Kathleen A, Ebrahimi-Nik, Hakimeh, Sun, Meng, Liu, Yue, Klinge, Kelly, Aguado, Jacqueline, Muscato, Audrey J, Tiwari, Payal, Avila-Monge, Omar, Colvin, Kayla J, Olander, Kira, Halliwill, Kyle, Klahn, Joseph, Schutte, Alexander, Paddock, Marcia N, Powell, Jonathan, Hamel, Keith M, Frost, Jennifer M, Yates, Kathleen B, Kym, Philip R, Manguso, Robert T, Baumgartner, Christina K
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
1403-A PTPN2/N1 inhibitor ABBV-CLS-484 unleashes potent anti-tumor immunity
Ebrahimi-Nik, Hakimeh, Baumgartner, Christina K, Iracheta-Vellve, Arvin, Hamel, Keith M, Olander, Kira, Davis, Thomas GR, McGuire, Kathleen A, Halvorsen, Geoff T, Avila, Omar I, Patel, Chirag, Kim, Sarah, Kammula, Ashwin V, Muscato, Audrey J, Halliwill, Kyle, Geda, Prasanthi, Klinge, Kelly, Xiong, Zhaoming, Duggan, Ryan, Mu, Liang, Yeary, Mitchell D, Patti, James C, Balon, Tyler M, Mathew, Rebecca, Backus, Carey, Kennedy, Domenick, Chen, Angeline, Longenecker, Kenton, Klahn, Joseph, Hrusch, Cara, Krishnan, Navasona, Hutchins, Charles W, Aguado, Jacqueline, Bulic, Marinka, Tiwari, Payal, Colvin, Kayla J, Chuong, Cun Lan, Kohnle, Ian C, Rees, Matthew G, Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A, Wu, Meng-Ju, Sen, Debattama R, Griffin, Gabriel K, El-Bardeesy, Nabeel, Trusk, Patricia, Sun, Meng, Liu, Yue, Decker, Joshua H, Yang, Yi, Fossey, Stacey, Qiu, Wei, Sun, Qi, Paddock, Marcia N, Farney, Elliot P, Beauregard, Clay, Frost, Jennifer M, Yates, Kathleen B, Kym, Philip R, Manguso, Robert T
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Pre-Existing Anti-FVIII Immunity Alters Therapeutic Platelet-Targeted FVIII Engraftment in the System Preconditioned with Busulfan Alone through Cytotoxic CD8 T Cells
Jing, Weiqing, Baumgartner, Christina, Xue, Feng, Schroeder, Jocelyn A., Shi, Qizhen
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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