Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis
Bachelez, Hervé, Choon, Siew-Eng, Marrakchi, Slaheddine, Burden, A. David, Tsai, Tsen-Fang, Morita, Akimichi, Turki, Hamida, Hall, David B, Shear, Michael, Baum, Patrick, Padula, Steven J, Thoma, Christian
Published in The New England journal of medicine (07.03.2019)
Published in The New England journal of medicine (07.03.2019)
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Urinary Exosomal miRNA Signature in Type II Diabetic Nephropathy Patients
Delić, Denis, Eisele, Claudia, Schmid, Ramona, Baum, Patrick, Wiech, Franziska, Gerl, Martin, Zimdahl, Heike, Pullen, Steven S, Urquhart, Richard
Published in PloS one (01.03.2016)
Published in PloS one (01.03.2016)
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Single-cell analysis implicates TH17-to-TH2 cell plasticity in the pathogenesis of palmoplantar pustulosis
McCluskey, Daniel, Benzian-Olsson, Natashia, Mahil, Satveer K., Hassi, Niina Karoliina, Wohnhaas, Christian T., Burden, A. David, Griffiths, Christopher E.M., Ingram, John R., Levell, Nick J., Parslew, Richard, Pink, Andrew E., Reynolds, Nick J., Warren, Richard B., Visvanathan, Sudha, Baum, Patrick, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca
Published in Journal of allergy and clinical immunology (01.10.2022)
Published in Journal of allergy and clinical immunology (01.10.2022)
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Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells
Wohnhaas, Christian T., Gindele, Julia A., Kiechle, Tobias, Shen, Yang, Leparc, Germán G., Stierstorfer, Birgit, Stahl, Heiko, Gantner, Florian, Viollet, Coralie, Schymeinsky, Jürgen, Baum, Patrick
Published in International journal of molecular sciences (16.07.2021)
Published in International journal of molecular sciences (16.07.2021)
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Journal Article
Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients
Delić, Denis, Wolk, Kerstin, Schmid, Ramona, Gabrielyan, Ogsen, Christou, Demetrios, Rieber, Kathrin, Rolser, Marcel, Jakob, Ines, Wiech, Franziska, Griesser, Manuela, Wohnhaas, Christian, Kokolakis, Georgios, Witte-Händel, Ellen, Baum, Patrick, Sabat, Robert
Published in Journal of dermatological science (01.01.2020)
Published in Journal of dermatological science (01.01.2020)
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Exosomal miRNAs as Potential Biomarkers to Monitor Phosphodiesterase 5 Inhibitor Induced Anti-Fibrotic Effects on CCl4 Treated Rats
Broermann, Andre, Schmid, Ramona, Gabrielyan, Ogsen, Sakowski, Marlene, Eisele, Claudia, Keller, Sascha, Wolff, Michael, Baum, Patrick, Stierstorfer, Birgit, Huber, Jochen, Krämer, Bernhard K., Hocher, Berthold, Streicher, Ruediger, Delić, Denis
Published in International journal of molecular sciences (01.01.2021)
Published in International journal of molecular sciences (01.01.2021)
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Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis
Koop, Kristina, Enderle, Karin, Hillmann, Miriam, Ruspeckhofer, Laura, Vieth, Michael, Sturm, Gregor, Trajanoski, Zlatko, Kühl, Anja A, Atreya, Raja, Leppkes, Moritz, Baum, Patrick, Roy, Janine, Martin, Andrea, Neurath, Markus F, Neufert, Clemens
Published in Frontiers in immunology (03.05.2023)
Published in Frontiers in immunology (03.05.2023)
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Journal Article
Monocyte-derived alveolar macrophages are key drivers of smoke-induced lung inflammation and tissue remodeling
Wohnhaas, Christian T, Baßler, Kevin, Watson, Carolin K, Shen, Yang, Leparc, Germán G, Tilp, Cornelia, Heinemann, Fabian, Kind, David, Stierstorfer, Birgit, Delić, Denis, Brunner, Thomas, Gantner, Florian, Schultze, Joachim L, Viollet, Coralie, Baum, Patrick
Published in Frontiers in immunology (2024)
Published in Frontiers in immunology (2024)
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Journal Article
Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation
Baßler, Kevin, Fujii, Wataru, Kapellos, Theodore S, Dudkin, Erika, Reusch, Nico, Horne, Ari, Reiz, Benedikt, Luecken, Malte D, Osei-Sarpong, Collins, Warnat-Herresthal, Stefanie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Wagner, Allon, Günther, Patrick, Pizarro, Carmen, Schreiber, Tina, Knoll, Rainer, Holsten, Lisa, Kröger, Charlotte, De Domenico, Elena, Becker, Matthias, Händler, Kristian, Wohnhaas, Christian T, Baumgartner, Florian, Köhler, Meike, Theis, Heidi, Kraut, Michael, Wadsworth, 2nd, Marc H, Hughes, Travis K, Ferreira, Humberto J, Hinkley, Emily, Kaltheuner, Ines H, Geyer, Matthias, Thiele, Christoph, Shalek, Alex K, Feißt, Andreas, Thomas, Daniel, Dickten, Henning, Beyer, Marc, Baum, Patrick, Yosef, Nir, Aschenbrenner, Anna C, Ulas, Thomas, Hasenauer, Jan, Theis, Fabian J, Skowasch, Dirk, Schultze, Joachim L
Published in Frontiers in immunology (28.07.2022)
Published in Frontiers in immunology (28.07.2022)
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Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3
Schmid, Ramona, Baum, Patrick, Ittrich, Carina, Fundel-Clemens, Katrin, Huber, Wolfgang, Brors, Benedikt, Eils, Roland, Weith, Andreas, Mennerich, Detlev, Quast, Karsten
Published in BMC genomics (02.06.2010)
Published in BMC genomics (02.06.2010)
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ITPA Genotypes Predict Anemia but Do Not Affect Virological Response with Interferon-Free Faldaprevir, Deleobuvir, and Ribavirin for HCV Infection
Asselah, Tarik, Zeuzem, Stefan, Soriano, Vicente, Bronowicki, Jean-Pierre, Lohse, Ansgar W, Müllhaupt, Beat, Schuchmann, Marcus, Bourlière, Marc, Buti, Maria, Roberts, Stuart K, Gane, Edward J, Stern, Jerry O, Voss, Florian, Baum, Patrick, Gallivan, John-Paul, Böcher, Wulf O, Mensa, Federico J
Published in PloS one (09.12.2015)
Published in PloS one (09.12.2015)
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Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization
Baum, Patrick, Schmid, Ramona, Ittrich, Carina, Rust, Werner, Fundel-Clemens, Katrin, Siewert, Susanne, Baur, Martin, Mara, Lisa, Gruenbaum, Lore, Heckel, Armin, Eils, Roland, Kontermann, Roland E, Roth, Gerald J, Gantner, Florian, Schnapp, Andreas, Park, John E, Weith, Andreas, Quast, Karsten, Mennerich, Detlev
Published in PloS one (10.12.2010)
Published in PloS one (10.12.2010)
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Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis
Baum, Patrick, Visvanathan, Sudha, Garcet, Sandra, Roy, Janine, Schmid, Ramona, Bossert, Sebastian, Lang, Benjamin, Bachelez, Hervé, Bissonnette, Robert, Thoma, Christian, Krueger, James G.
Published in Journal of allergy and clinical immunology (01.04.2022)
Published in Journal of allergy and clinical immunology (01.04.2022)
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Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation
Scheibe, Kristina, Kersten, Christina, Schmied, Anabel, Vieth, Michael, Primbs, Tatjana, Carlé, Birgitta, Knieling, Ferdinand, Claussen, Jing, Klimowicz, Alexander C., Zheng, Jie, Baum, Patrick, Meyer, Sebastian, Schürmann, Sebastian, Friedrich, Oliver, Waldner, Maximilian J., Rath, Timo, Wirtz, Stefan, Kollias, George, Ekici, Arif B., Atreya, Raja, Raymond, Ernest L., Mbow, M. Lamine, Neurath, Markus F., Neufert, Clemens
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2019)
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DMSO cryopreservation is the method of choice to preserve cells for droplet-based single-cell RNA sequencing
Wohnhaas, Christian T., Leparc, Germán G., Fernandez-Albert, Francesc, Kind, David, Gantner, Florian, Viollet, Coralie, Hildebrandt, Tobias, Baum, Patrick
Published in Scientific reports (23.07.2019)
Published in Scientific reports (23.07.2019)
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Journal Article
Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab
Visvanathan, Sudha, Baum, Patrick, Vinisko, Richard, Schmid, Ramona, Flack, Mary, Lalovic, Bojan, Kleiner, Oliver, Fuentes-Duculan, Judilyn, Garcet, Sandra, Davis, Justin W., Grebe, Kristie M., Fine, Jay S., Padula, Steven J., Krueger, James G.
Published in Journal of allergy and clinical immunology (01.06.2019)
Published in Journal of allergy and clinical immunology (01.06.2019)
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Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile
Skaug, Brian, Khanna, Dinesh, Swindell, William R, Hinchcliff, Monique E, Frech, Tracy M, Steen, Virginia D, Hant, Faye N, Gordon, Jessica K, Shah, Ami A, Zhu, Lisha, Zheng, W Jim, Browning, Jeffrey L, Barron, Alexander M S, Wu, Minghua, Visvanathan, Sudha, Baum, Patrick, Franks, Jennifer M, Whitfield, Michael L, Shanmugam, Victoria K, Domsic, Robyn T, Castelino, Flavia V, Bernstein, Elana J, Wareing, Nancy, Lyons, Marka A, Ying, Jun, Charles, Julio, Mayes, Maureen D, Assassi, Shervin
Published in Annals of the rheumatic diseases (01.03.2020)
Published in Annals of the rheumatic diseases (01.03.2020)
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Journal Article
Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease
Vergnano, Marta, Mockenhaupt, Maja, Benzian-Olsson, Natashia, Paulmann, Maren, Grys, Katarzyna, Mahil, Satveer K., Chaloner, Charlotte, Barbosa, Ines A., August, Suzannah, Burden, A. David, Choon, Siew-Eng, Cooper, Hywel, Navarini, Alex A., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Abraham, Thamir, Ali, Mahmud, August, Suzannah, Baudry, David, Bewley, Anthony, Cooper, Hywel, Griffiths, Christopher E.M., Ingram, John, Kelly, Susan, Korshid, Mohsen, Ladoyanni, Effie, McKenna, John, Meynell, Freya, Parslew, Richard, Patel, Prakash, Pushparajah, Angela, Reynolds, Nick, Smith, Catherine, Wahie, Shyamal, Warren, Richard, Wright, Andrew, Huffmeier, Ulrike, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca
Published in American journal of human genetics (03.09.2020)
Published in American journal of human genetics (03.09.2020)
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Journal Article
Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pilot Study
Mrowietz, Ulrich, Burden, A. David, Pinter, Andreas, Reich, Kristian, Schäkel, Knut, Baum, Patrick, Datsenko, Yakov, Deng, Hongjie, Padula, Steven J., Thoma, Christian, Bissonnette, Robert
Published in Dermatology and therapy (01.04.2021)
Published in Dermatology and therapy (01.04.2021)
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