One Target—Two Different Binding Modes: Structural Insights into Gevokizumab and Canakinumab Interactions to Interleukin-1β
Blech, Michaela, Peter, Daniel, Fischer, Peter, Bauer, Margit M.T., Hafner, Mathias, Zeeb, Markus, Nar, Herbert
Published in Journal of molecular biology (09.01.2013)
Published in Journal of molecular biology (09.01.2013)
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Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications
Blech, Michaela, Seeliger, Daniel, Kistler, Barbara, Bauer, Margit M T, Hafner, Mathias, Hörer, Stefan, Zeeb, Markus, Nar, Herbert, Park, John E
Published in Biochemical journal (15.10.2012)
Published in Biochemical journal (15.10.2012)
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Differential analyte derivatization enables unbiased MALDI-TOF-based high-throughput screening: A proof-of-concept study for the discovery of catechol-o-methyltransferase inhibitors
Winter, Martin, Simon, Roman P., Wang, Yuting, Bretschneider, Tom, Bauer, Margit, Magarkar, Aniket, Reindl, Wolfgang, Fernández-Montalván, Amaury, Montel, Florian, Büttner, Frank H.
Published in SLAS discovery (01.07.2022)
Published in SLAS discovery (01.07.2022)
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Littoral Cell Angioma and Angiosarcoma of the Spleen: Report of Two Cases in Siblings and Review of the Literature
Kranzfelder, Michael, Bauer, Margit, Richter, Thomas, Rudelius, Martina, Huth, Martin, Wagner, Peter, Friess, Helmut, Stadler, Josef
Published in Journal of gastrointestinal surgery (01.04.2012)
Published in Journal of gastrointestinal surgery (01.04.2012)
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Cystic periventricular leukomalacia in preterm infants: An analysis of obstetric risk factors
Bauer, Margit, Fast, Christa, Haas, Josef, Resch, Bernhard, Lang, Uwe, Pertl, Barbara
Published in Early human development (01.03.2009)
Published in Early human development (01.03.2009)
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Journal Article
Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation
Nar, Herbert, Bauer, Margit, Stassen, Jean-Marie, Lang, Dietmar, Gils, Ann, Declerck, Paul J
Published in Journal of molecular biology (31.03.2000)
Published in Journal of molecular biology (31.03.2000)
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Journal Article
The 2.3 Å Crystal Structure of the Catalytic Domain of Recombinant Two-chain Human Tissue-type Plasminogen Activator
Lamba, Doriano, Bauer, Margit, Huber, Robert, Fischer, Stephan, Rudolph, Rainer, Kohnert, Ulrich, Bode, Wolfram
Published in Journal of molecular biology (26.04.1996)
Published in Journal of molecular biology (26.04.1996)
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Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis
Rübbelke, Martin, Fiegen, Dennis, Bauer, Margit, Binder, Florian, Hamilton, James, King, Jim, Thamm, Sven, Nar, Herbert, Zeeb, Markus
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2020)
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Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain
Rübbelke, Martin, Hamilton, James, Binder, Florian, Bauer, Margit, King, Jim, Nar, Herbert, Zeeb, Markus
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability
Heine, Niklas, Weber, Alexander, Pautsch, Alexander, Gottschling, Dirk, Uphues, Ingo, Bauer, Margit, Ebenhoch, Rebecca, Magarkar, Aniket, Nosse, Bernd, Kley, Jörg Thomas
Published in Bioorganic & medicinal chemistry letters (01.11.2024)
Published in Bioorganic & medicinal chemistry letters (01.11.2024)
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Crystal structures of human and mouse ketohexokinase provide a structural basis for species‐ and isoform‐selective inhibitor design
Ebenhoch, Rebecca, Bauer, Margit, Romig, Helmut, Gottschling, Dirk, Kley, Jörg Thomas, Heine, Niklas, Weber, Alexander, Uphues, Ingo, Nar, Herbert, Pautsch, Alexander
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2023)
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2023)
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1001 Endoscopic Intraluminal Therapy of a Dislocated Magnetic Antireflux Device Causing Severe Dysphagia
Meining, Alexander, Bauer, Margit, Feussner, Hubertus
Published in Gastrointestinal endoscopy (01.05.2015)
Published in Gastrointestinal endoscopy (01.05.2015)
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Endoluminal perforation of a magnetic antireflux device
Bauer, Margit, Meining, Alexander, Kranzfelder, Michael, Jell, Alissa, Schirren, Rebekka, Wilhelm, Dirk, Friess, Helmut, Feussner, Hubertus
Published in Surgical endoscopy (01.12.2015)
Published in Surgical endoscopy (01.12.2015)
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A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I
Ebenhoch, Rebecca, Prinz, Simone, Kaltwasser, Susann, Mills, Deryck J., Meinecke, Robert, Rübbelke, Martin, Reinert, Dirk, Bauer, Margit, Weixler, Lisa, Zeeb, Markus, Vonck, Janet, Nar, Herbert
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
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Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP
Ebenhoch, Rebecca, Bauer, Margit, Reinert, Dirk, Kersting, Anja, Huber, Sylwia, Schmid, Angela, Hinz, Ingo, Feiler, Marisa, Müller, Kathrin, Nar, Herbert
Published in Journal of structural biology (01.03.2021)
Published in Journal of structural biology (01.03.2021)
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A hybrid screening approach for very small fragments - X-ray and Computational Screening on FKBP51
Draxler, Sebastian Wolfgang, Bauer, Margit, Eickmeier, Christian, Nadal, Simon, Nar, Herbert, Rangel, Daniel, Seeliger, Daniel, Zeeb, Markus, Fiegen, Dennis
Published in Journal of medicinal chemistry (11.06.2020)
Published in Journal of medicinal chemistry (11.06.2020)
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A probe-based electromagnetic navigation system to integrate computed tomography during upper gastrointestinal endoscopy
Kranzfelder, Michael, Wilhelm, Dirk, Doundoulakis, Manos, Schneider, Armin, Bauer, Margit, Reiser, Silvano, Meining, Alexander, Feussner, Hubertus
Published in Endoscopy (01.04.2014)
Published in Endoscopy (01.04.2014)
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Crystallographic Evidence That the F2 Kringle Catalytic Domain Linker of Prothrombin Does Not Cover the Fibrinogen Recognition Exosite (∗)
van de Locht, Andreas, Stubbs, Milton T., Bauer, Margit, Bode, Wolfram
Published in The Journal of biological chemistry (16.02.1996)
Published in The Journal of biological chemistry (16.02.1996)
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