Novel imidazo[1,5-a]quinoxaline derivatives: SAR, selectivity and modeling challenges en route to the identification of an?5-GABAA receptor NAM
Karolyi, Benedek Imre, Potor, Attila, Kapus, Gabor Laszlo, Fodor, Laszlo, Bobok, Amrita, Kramos, Balazs, Magdo, Ildiko, Bata, Imre, Szabo, Gyorgy
Published in Bioorganic & medicinal chemistry letters (15.01.2023)
Published in Bioorganic & medicinal chemistry letters (15.01.2023)
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Journal Article
Novel imidazo[1,5-a]quinoxaline derivatives: SAR, selectivity and modeling challenges en route to the identification of an α5-GABAA receptor NAM
Károlyi, Benedek Imre, Potor, Attila, Kapus, Gábor László, Fodor, László, Bobok, Amrita, Krámos, Balázs, Magdó, Ildikó, Bata, Imre, Szabó, György
Published in Bioorganic & medicinal chemistry letters (15.01.2023)
Published in Bioorganic & medicinal chemistry letters (15.01.2023)
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New V1a receptor antagonist. Part 2. Identification and optimization of triazolobenzazepines
Bozó, Éva, Baska, Ferenc, Lövei, Klára, Szántó, Gábor, Domány-Kovács, Katalin, Kurkó, Dalma, Szondiné Kordás, Krisztina, Szokoli, Teodóra, Bata, Imre
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
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Journal Article
New V1 a receptor antagonist. Part 2. Identification and optimization of triazolobenzazepines
Bozo, Eva, Baska, Ferenc, Lovei, Klara, Szanto, Gabor, Domany-Kovacs, Katalin, Kurko, Dalma, Kordas, Krisztina Szondine, Szokoli, Teodora, Bata, Imre
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
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Journal Article
GABAA α5 수용체 조절제로서의 바이사이클릭 아민 유도체
KAPUS GABOR LASZLO, POTOR ATTILA, SZABO GYORGY, BATA IMRE, ERDELYI PETER, ELIAS OLIVER, TUROS GYORGY ISTVAN
Year of Publication 20.06.2024
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Year of Publication 20.06.2024
Patent
Discovery and Characterization of RGH-122, a Potent, Selective, and Orally Bioavailable V1a Receptor Antagonist
Baska, Ferenc, Bozó, Éva, Szeleczky, Zsolt, Szántó, Gábor, Vukics, Krisztina, Szakács, Zoltán, Domány-Kovács, Katalin, Kurkó, Dalma, Vass, Elemér, Thán, Márta, Vastag, Mónika, Temesvári, Krisztina, Lévai, Sándor, Halász, Attila Sándor, Szondiné Kordás, Krisztina, Román, Viktor, Greiner, István, Bata, Imre
Published in Journal of medicinal chemistry (11.01.2024)
Published in Journal of medicinal chemistry (11.01.2024)
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Multiparameter Optimization of Naphthyridine Derivatives as Selective α5-GABA A Receptor Negative Allosteric Modulators
Szabó, György, Éliás, Olivér, Erdélyi, Péter, Potor, Attila, Túrós, György I, Károlyi, Benedek I, Varró, Gábor, Vaskó, Ágnes Gy, Bata, Imre, Kapus, Gábor L, Dohányos, Zoltán, Bobok, Amrita Á, Fodor, László, Thán, Márta, Vastag, Mónika, Komlódi, Zsolt, Soukupné Kedves, Rita É, Makó, Éva, Süveges, Brigitta, Greiner, István
Published in Journal of medicinal chemistry (09.06.2022)
Published in Journal of medicinal chemistry (09.06.2022)
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Journal Article
Identification of Triazolopyridines as Selective α5-GABA A Receptor Negative Allosteric Modulators by a Hybridization Approach
Szabó, György, Károlyi, Benedek Imre, Vaskó, Ágnes Gyöngyvér, Potor, Attila, Vukics, Krisztina, Kapus, Gábor László, Fodor, László, Bobok, Amrita, Vastag, Mónika, Bata, Imre
Published in ACS chemical neuroscience (04.01.2023)
Published in ACS chemical neuroscience (04.01.2023)
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Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560)
Ledneczki, István, Némethy, Zsolt, Molnár, Katalin Dudásné, Tapolcsányi, Pál, Ilkei, Viktor, Vágó, István, Kolok, Sándor, Thán, Márta, Laszy, Judit, Balázs, Ottilia, Krámos, Balázs, Szigetvári, Áron, Bata, Imre, Makó, Attila, Visegrády, András, Fodor, László, Vastag, Mónika, Lévay, György, Lendvai, Balázs, Greiner, István, Éles, János
Published in Journal of medicinal chemistry (14.12.2023)
Published in Journal of medicinal chemistry (14.12.2023)
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Novel-Type GABA B PAMs: Structure-Activity Relationship in Light of the Protein Structure
Krámos, Balázs, Hadady, Zsuzsa, Makó, Attila, Szántó, Gábor, Felföldi, Nóra, Magdó, Ildikó, Bobok, Amrita Ágnes, Bata, Imre, Román, Viktor, Visegrády, András, Keserű, György M, Greiner, István, Éles, János
Published in ACS medicinal chemistry letters (14.03.2024)
Published in ACS medicinal chemistry letters (14.03.2024)
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New V1a receptor antagonist. Part 1. Synthesis and SAR development of urea derivatives
Szántó, Gábor, Makó, Attila, Baska, Ferenc, Bozó, Éva, Domány-Kovács, Katalin, Kurkó, Dalma, Cselenyák, Attila, Mohácsi, Réka, Kordás, Krisztina Szondiné, Bata, Imre
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
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Synthesis and Characterization of New V1A Antagonist Compounds: The Separation of Four Atropisomeric Stereoisomers
Szeleczky, Zsolt, Szakács, Zoltán, Bozó, Éva, Baska, Ferenc, Vukics, Krisztina, Lévai, Sándor, Temesvári, Krisztina, Vass, Elemér, Béni, Zoltán, Krámos, Balázs, Magdó, Ildikó, Szántay, Csaba, Kóti, János, Domány-Kovács, Katalin, Greiner, István, Bata, Imre
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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Journal Article
Synthesis and Characterization of New V 1A Antagonist Compounds: The Separation of Four Atropisomeric Stereoisomers
Szeleczky, Zsolt, Szakács, Zoltán, Bozó, Éva, Baska, Ferenc, Vukics, Krisztina, Lévai, Sándor, Temesvári, Krisztina, Vass, Elemér, Béni, Zoltán, Krámos, Balázs, Magdó, Ildikó, Szántay, Csaba, Kóti, János, Domány-Kovács, Katalin, Greiner, István, Bata, Imre
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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Identification of Triazolopyridines as Selective α5-GABAA Receptor Negative Allosteric Modulators by a Hybridization Approach
Szabó, György, Károlyi, Benedek Imre, Vaskó, Ágnes Gyöngyvér, Potor, Attila, Vukics, Krisztina, Kapus, Gábor László, Fodor, László, Bobok, Amrita, Vastag, Mónika, Bata, Imre
Published in ACS chemical neuroscience (04.01.2023)
Published in ACS chemical neuroscience (04.01.2023)
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Journal Article
Multiparameter Optimization of Naphthyridine Derivatives as Selective α5-GABAA Receptor Negative Allosteric Modulators
Szabó, György, Éliás, Olivér, Erdélyi, Péter, Potor, Attila, Túrós, György I., Károlyi, Benedek I., Varró, Gábor, Vaskó, Ágnes Gy, Bata, Imre, Kapus, Gábor L., Dohányos, Zoltán, Bobok, Amrita Á., Fodor, László, Thán, Márta, Vastag, Mónika, Komlódi, Zsolt, Soukupné Kedves, Rita É., Makó, Éva, Süveges, Brigitta, Greiner, István
Published in Journal of medicinal chemistry (09.06.2022)
Published in Journal of medicinal chemistry (09.06.2022)
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Journal Article
Novel-Type GABAB PAMs: Structure–Activity Relationship in Light of the Protein Structure
Krámos, Balázs, Hadady, Zsuzsa, Makó, Attila, Szántó, Gábor, Felföldi, Nóra, Magdó, Ildikó, Bobok, Amrita Ágnes, Bata, Imre, Román, Viktor, Visegrády, András, Keserű, György M., Greiner, István, Éles, János
Published in ACS medicinal chemistry letters (14.03.2024)
Published in ACS medicinal chemistry letters (14.03.2024)
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New P2X3 receptor antagonists. Part 2: Identification and SAR of quinazolinones
Szántó, Gábor, Makó, Attila, Vágó, István, Hergert, Tamás, Bata, Imre, Farkas, Bence, Kolok, Sándor, Vastag, Mónika
Published in Bioorganic & medicinal chemistry letters (15.08.2016)
Published in Bioorganic & medicinal chemistry letters (15.08.2016)
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I. Discovery of a novel series of CXCR3 antagonists. Multiparametric optimization of N,N-disubstituted benzylamines
Bata, Imre, Tömösközi, Zsuzsanna, Buzder-Lantos, Péter, Vasas, Attila, Szeleczky, Gábor, Bátori, Sándor, Barta-Bodor, Veronika, Balázs, László, Ferenczy, György G.
Published in Bioorganic & medicinal chemistry letters (15.11.2016)
Published in Bioorganic & medicinal chemistry letters (15.11.2016)
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Discovery of New Heterocyclic Ring Systems as Novel and Potent V 1A Receptor Antagonists
Baska, Ferenc, Szántó, Gábor, Bozó, Éva, Szakács, Zoltán, Dékány, Miklós, Szondiné Kordás, Krisztina, Domány-Kovács, Katalin, Kurkó, Dalma, Hodoscsek, Barbara, Magdó, Ildikó, Krámos, Balázs, Béni, Zoltán, Vastag, Mónika, Bata, Imre
Published in ACS chemical neuroscience (04.11.2020)
Published in ACS chemical neuroscience (04.11.2020)
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